Protein Alignment Zip48C and SLC39A14

DIOPT Version :10

• Sequence 1: NP_610712.1
• Gene: Zip48C / 36273
• FlyBaseID: FBgn0033665
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_001338586.1
• Gene: SLC39A14 / 23516
• HGNCID: 20858
• Length: 502
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 87/369 - (23%)
• Similarity: 151/369 - (40%)
• Gaps: 77/369 - (20%)

  Fly     4 GYG--PVTQALLGTLLTWGLTAAGAALVIFVRGN-QRRSLDAALGFAAGVMIAASFWSLLKPAIE 65
            |||  .||...|.:||       ||::|.|::.. .:|.|...:..|.|.:.:.:.:.|:..|
Human   165 GYGLLCVTVISLCSLL-------GASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA-- 220

  Fly    66 MAESSHLYGVYAFLPVAGGFLLGSIFVYG-------CDKLMSYLGLNSTNMMIQMTQSKAKADIA 123
                      :.|.|:...::..|..|:|       .:|::..| |...|.........|...:.
Human   221 ----------FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKIL-LKQKNEHHHGHSHYASESLP 274

  Fly   124 IEDSKRNGVAPDRLASKSLDSFSDCLSVQHSGESRRRKKGASINEMEQCTYTTPEEQQRAEDALS 188
            .:..:..||. ::|.:..||.    :..||. .|....|...::|.......:.::.|.::.|..
Human   275 SKKDQEEGVM-EKLQNGDLDH----MIPQHC-SSELDGKAPMVDEKVIVGSLSVQDLQASQSACY 333

  Fly   189 QWKRI---------MLLVVAITVHNIPEGLAVGVSFGAIGSTNSSTFESARNLAIGIGIQNFPEG 244
            ..|.:         .::.::..:||..:|||:|.||      ..|.|:.. :.::.|..:.||..
Human   334 WLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASF------TVSVFQGI-STSVAILCEEFPHE 391

  Fly   245 LAVSLPLHAAGFSVKRALWYGQLS------GMVEPIFGVLGAVAVTFANLILPYALSFAAGAMIY 303
            |...:.|..||.|:::||::..||      |:.   ||:|.....: ||.|  :||  |.|..:|
Human   392 LGDFVILLNAGMSIQQALFFNFLSACCCYLGLA---FGILAGSHFS-ANWI--FAL--AGGMFLY 448

  Fly   304 IVSDDILPEAHA-----SGNGT------IATWGTVSGFLIMMCL 336
            |...|:.||.:.     ...|:      |...|.::||.||:.|
Human   449 ISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zip48C	NP_610712.1	ZupT	23..339	CDD:440197	79/348 (23%)
SLC39A14	NP_001338586.1	Zip	161..493	CDD:396884	87/369 (24%)