DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zip48C and Slc39a7

DIOPT Version :9

Sequence 1:	NP_610712.1	Gene:	Zip48C / 36273	FlyBaseID:	FBgn0033665	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001071177.1	Gene:	Slc39a7 / 14977	MGIID:	95909	Length:	476	Species:	Mus musculus

Alignment Length:	381	Identity:	89/381 - (23%)
Similarity:	135/381 - (35%)	Gaps:	102/381 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LGTLLTWG-------LTAAGAALVIF---VRGN---QRRSLDAALGFAAGVMIAASFWSLLKPAI 64
            |.|:..|.       |.:|....|:|   |..|   .|..|...|.||:|.::..:|..|:..|:
Mouse   137 LDTVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHAL 201

  Fly    65 EMAESSH------------------------LYGVYAFLPVAGGFLLGSIFVYGCDKLMSYL-GL 104
            | ..|.|                        |.|:.|||.|              :|.:.:: |.
Mouse   202 E-PHSHHAPEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVV--------------EKFVRHVKGG 251

  Fly   105 NSTNMMIQMTQSKAKAD-IAIEDSKRNGVAPDR--LASKSLDSFSDCLSVQHSGESRRRKKGASI 166
            :.        .|....| .|..||..:|   ||  .:||...|..:...|   |..|:|:.|.:.
Mouse   252 HG--------HSHGHGDRHAHGDSHTHG---DRHECSSKEKPSTEEEKEV---GGLRKRRGGNTG 302

  Fly   167 NEMEQCTYTTPEEQQRAEDALSQWKRI--MLLVVAITVHNIPEGLAVGVSFGAIGSTNSSTFESA 229
            .........:|||::...|.     |:  .|.:.|...||..:|||:|.|           |...
Mouse   303 PRDGPVKPQSPEEEKAGSDL-----RVSGYLNLAADLAHNFTDGLAIGAS-----------FRGG 351

  Fly   230 RNLAI----GIGIQNFPEGLAVSLPLHAAGFSVKRAL------WYGQLSGMVEPIFGVLGAVAVT 284
            |.|.|    .:.:...|..:.....|..:|.|.|:|:      ..|.|:|....:....|||...
Mouse   352 RGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLVTAIGALAGTACALLTEGGAVDSD 416

  Fly   285 FANLILP-YALSFAAGAMIYIVSDDILPEAHASGN---GTIATWGTVSGFLIMMCL 336
            .|....| :.|.|.||..||:.:..:|||.....:   ..:...|.:.|..:|:.:
Mouse   417 VAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVAMMVLI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zip48C	NP_610712.1	ZupT	23..340	CDD:223505	85/364 (23%)
Slc39a7	NP_001071177.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	35..131
		Zip	140..453	CDD:280666	84/357 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..320		20/84 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810