DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1alpha1 and IFM1

DIOPT Version :9

Sequence 1:	NP_001286321.1	Gene:	eEF1alpha1 / 36271	FlyBaseID:	FBgn0284245	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_014619.1	Gene:	IFM1 / 854135	SGDID:	S000005383	Length:	676	Species:	Saccharomyces cerevisiae

Alignment Length:	315	Identity:	71/315 - (22%)
Similarity:	115/315 - (36%)	Gaps:	121/315 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITID 74
            :.::||||.||:|...:|            .|....|||.|                   |||..
Yeast   148 VTIMGHVDHGKTTIIDYL------------RKSSVVAQEHG-------------------GITQH 181

  Fly    75 IALWKFETAK--YYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHA 137
            |..::....|  ..:|.:|.|||..|:|....|.:..|..||:|:.                |.:
Yeast   182 IGAFQITAPKSGKKITFLDTPGHAAFLKMRERGANITDIIVLVVSV----------------EDS 230

  Fly   138 LLAFTL-GVK-------QLIVGVNKMDSSEPPYSEARYEEIKKEVSSYI------KKIGYNPAAV 188
            |:..|| .:|       ::|:.:.|:|  ..|..:.|.::|:|.::..|      :|||   ..|
Yeast   231 LMPQTLEAIKHAKNSGNEMIIAITKID--RIPQPKEREKKIEKVINDLIVQGIPVEKIG---GDV 290

  Fly   189 AFVPISGWHGDNM--LEPS------------TNMP--WFKGWKVERKEGNADGKTLIDALDAILP 237
            ..:|||...|:||  ||.|            .|.|  ..:||.:|.
Yeast   291 QVIPISAKTGENMDLLEESIVLLSEVMDIRAENSPKTIAEGWIIES------------------- 336

  Fly   238 PARPTDKALRLPLQDVYKIGGIGTVPVGRVETGVLKPGTVVVFAPANITTEVKSV 292
                         |...::|.:.||   .|:.|.|:.|.:::.  .|...::|::
Yeast   337 -------------QVKKQVGNVATV---LVKKGTLQKGKILIC--GNTFCKIKNL 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	71/315 (23%)
IFM1	NP_014619.1	IF2_N	63..114	CDD:398434
IFM1	NP_014619.1	InfB	141..676	CDD:223606	71/315 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910