DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1alpha1 and AT5G60390

DIOPT Version :9

Sequence 1:	NP_001286321.1	Gene:	eEF1alpha1 / 36271	FlyBaseID:	FBgn0284245	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_001119464.1	Gene:	AT5G60390 / 836161	AraportID:	AT5G60390	Length:	449	Species:	Arabidopsis thaliana

Alignment Length:	463	Identity:	345/463 - (74%)
Similarity:	393/463 - (84%)	Gaps:	14/463 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKA 65
            |||||.||||||||||||||||||||||||.||||||.||:|||||.||.|.|||||||||||||
plant     1 MGKEKFHINIVVIGHVDSGKSTTTGHLIYKLGGIDKRVIERFEKEAAEMNKRSFKYAWVLDKLKA 65

  Fly    66 ERERGITIDIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKN 130
            |||||||||||||||||.|||.|:||||||||||||||||||||||||||:.:.||.|||||||:
plant    66 ERERGITIDIALWKFETTKYYCTVIDAPGHRDFIKNMITGTSQADCAVLIIDSTTGGFEAGISKD 130

  Fly   131 GQTREHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKKIGYNPAAVAFVPISG 195
            |||||||||||||||||:|...||||::.|.||:|||:||.||||||:||:||||..:.||||||
plant   131 GQTREHALLAFTLGVKQMICCCNKMDATTPKYSKARYDEIIKEVSSYLKKVGYNPDKIPFVPISG 195

  Fly   196 WHGDNMLEPSTNMPWFKGWKVERKEGNADGKTLIDALDAILPPARPTDKALRLPLQDVYKIGGIG 260
            :.||||:|.|||:.|:|            |.||::|||.|..|.||:||.|||||||||||||||
plant   196 FEGDNMIERSTNLDWYK------------GPTLLEALDQINEPKRPSDKPLRLPLQDVYKIGGIG 248

  Fly   261 TVPVGRVETGVLKPGTVVVFAPANITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYV 325
            ||||||||||::|||.||.|||..:||||||||||||:|.||:||||||||||||:||:|:||||
plant   249 TVPVGRVETGMIKPGMVVTFAPTGLTTEVKSVEMHHESLLEALPGDNVGFNVKNVAVKDLKRGYV 313

  Fly   326 AGDSKANPPKGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFAEIKEKVDRRSGKTTEEN 390
            |.:||.:|.||||:||:|||::||||||.|||.|||||||:|||.||:||..|:||||||..|:.
plant   314 ASNSKDDPAKGAANFTSQVIIMNHPGQIGNGYAPVLDCHTSHIAVKFSEILTKIDRRSGKEIEKE 378

  Fly   391 PKFIKSGDAAIVNLVPSKPLCVEAFQEFPPLGRFAVRDMRQTVAVGVIKAVNFKDASGGKVTKAA 455
            |||:|:|||.:|.:.|:||:.||.|.|:|||||||||||||||||||||:|:.||.:|.||||||
plant   379 PKFLKNGDAGMVKMTPTKPMVVETFSEYPPLGRFAVRDMRQTVAVGVIKSVDKKDPTGAKVTKAA 443

  Fly   456 EKATKGKK 463
            .|  ||.|
plant   444 VK--KGAK 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	341/455 (75%)
AT5G60390	NP_001119464.1	PTZ00141	1..446	CDD:185474	342/458 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	349	1.000	Domainoid score	I221
eggNOG	1	0.900	-	-		E1_COG5256
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	696	1.000	Inparanoid score	I134
OMA	1	1.010	-	-		QHG62187
OrthoDB	1	1.010	-	-		D1150082at2759
OrthoFinder	1	1.000	-	-		FOG0000314
OrthoInspector	1	1.000	-	-		mtm1025
orthoMCL	1	0.900	-	-		OOG6_100227
Panther	1	1.100	-	-	O	PTHR23115
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X149
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840