DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1alpha1 and eefsec

DIOPT Version :9

Sequence 1:	NP_001286321.1	Gene:	eEF1alpha1 / 36271	FlyBaseID:	FBgn0284245	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_001032513.1	Gene:	eefsec / 641497	ZFINID:	ZDB-GENE-051120-72	Length:	576	Species:	Danio rerio

Alignment Length:	342	Identity:	89/342 - (26%)
Similarity:	132/342 - (38%)	Gaps:	76/342 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERG 70
            ::.|:.|:|||||||::..            |.:......|            ..||....:|||
Zfish     8 LNFNVGVLGHVDSGKTSLA------------RALSSTASTA------------AFDKNPQSKERG 48

  Fly    71 ITIDIALWKFET-----------AKYY----VTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGT 120
            ||:|:....|..           .|.|    .|::|.|||...|:.:|.|....|..:|:|
Zfish    49 ITLDLGFSAFTVPLPEHLRESCGEKQYDSLQFTLVDCPGHASLIRTIIGGAQIIDLMMLVV---- 109

  Fly   121 GEFEAGISKNGQTR-EHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKKIGYN 184
                 .:.|..||: ...||...|...:::|.:||.|.......:|..:::.|.:...::...:.
Zfish   110 -----DVVKGMQTQTAECLLIGQLTCSRMVVILNKTDLLPSDKRQAAIDKMTKRMHKTLENTRFK 169

  Fly   185 PA---AVAFVPISGWHGDNMLEPSTNMPWFKGWKVERKEGNADGKT-LIDALDA--ILPPARPTD 243
            ..   |||..|      .....|.|:.|              .|.| |||.|.|  .||...|:.
Zfish   170 DCPIIAVAAKP------GGPEAPDTDEP--------------QGITELIDLLKAQSFLPHRDPSG 214

  Fly   244 KALRLPLQDVYKIGGIGTVPVGRVETGVLKPGTVVVFAPANITTEVKSVEMHHEALQEAVPGDNV 308
             :|.:.:...:.|.|.|||..|.:..|.|.....|......:|.:||||:|..:.:..|:.||.|
Zfish   215 -SLLMAVDHCFSIRGQGTVITGTILQGSLSVNDNVEIPALKVTRKVKSVQMFRKPVASAMQGDRV 278

  Fly   309 GFNVKNVSVKELRRGYV 325
            |..|.....|.|.||.|
Zfish   279 GVCVTQFDPKLLERGVV 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	89/342 (26%)
eefsec	NP_001032513.1	SelB_euk	10..202	CDD:206676	57/244 (23%)
		GTP_EFTU	11..201	CDD:278438	57/242 (24%)
		SelB_II	216..298	CDD:293897	27/80 (34%)
		eSelB_III	303..433	CDD:294009
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910