DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1alpha1 and CG4849

DIOPT Version :9

Sequence 1:	NP_001286321.1	Gene:	eEF1alpha1 / 36271	FlyBaseID:	FBgn0284245	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_651605.1	Gene:	CG4849 / 43358	FlyBaseID:	FBgn0039566	Length:	975	Species:	Drosophila melanogaster

Alignment Length:	199	Identity:	50/199 - (25%)
Similarity:	81/199 - (40%)	Gaps:	35/199 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITI 73
            |:.::||:..||:|....||       ::|..:||    .|.:...:|.   |.|..|:|||.:|
  Fly   133 NVALVGHLHHGKTTFVDCLI-------RQTHPQFE----TMEERQLRYT---DTLFTEQERGCSI 183

  Fly    74 -----DIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQT 133
                 .:.|...:...|.:.|.|.|||.:|..........:|..||.:.|.     .|:..|.:
  Fly   184 KATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAA-----EGVMLNTE- 242

  Fly   134 REHALLAFTLGVKQLI-VGVNKMD------SSEPPYSEARYEEIKKEVSSYIKKIGYNPAAVAFV 191
               .||...:..:|.| |.:||:|      ...|..:..:.:.|.:||:..:...|.....:...
  Fly   243 ---RLLKHAVQERQAITVCINKIDRLILELKLPPQDAYFKLKHIVEEVNGLLSTYGAPDDNLLVS 304

  Fly   192 PISG 195
            ||.|
  Fly   305 PILG 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	50/199 (25%)
CG4849	NP_651605.1	EFTUD2	4..111	CDD:292623
		PTZ00416	115..957	CDD:240409	50/199 (25%)
		Snu114p	132..340	CDD:206730	50/199 (25%)
		Translation_Factor_II_like	477..568	CDD:295476
		snRNP_III	589..660	CDD:293921
		EF2_IV_snRNP	660..837	CDD:238840
		eEF2_C_snRNP	832..911	CDD:239765
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464560
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930