DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1alpha1 and waw

DIOPT Version :9

Sequence 1:	NP_001286321.1	Gene:	eEF1alpha1 / 36271	FlyBaseID:	FBgn0284245	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_001027089.1	Gene:	waw / 3771960	FlyBaseID:	FBgn0024182	Length:	696	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	86/366 - (23%)
Similarity:	136/366 - (37%)	Gaps:	105/366 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKA 65
            |..|:|. |..:|.|||.||||....|:...|.|           |:..|:..     |||.|:.
  Fly    94 MPVERIR-NFSIIAHVDHGKSTLADRLLELTGAI-----------ARNGGQHQ-----VLDNLQV 141

  Fly    66 ERERGITIDIALWKFETAK---------YYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTG 121
            |||||||:     |.:||.         |.:.:||.|||.||...:....:..|..||:|.|..|
  Fly   142 ERERGITV-----KAQTASIFHRHKGQLYLLNLIDTPGHVDFSNEVSRSLAACDGVVLLVDACHG 201

  Fly   122 EFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKKIGYNPA 186
             .:|....|....:...||       ::..:||:|     ...|..:::.:::...   .|.:|
  Fly   202 -VQAQTVANYHLAKQRQLA-------VVPVLNKID-----IKHANPDQVCQDLKLL---FGIDP- 249

  Fly   187 AVAFVPISGWHGDNMLEPSTNMPWFKGWKVERKEGNADGKTLIDALDAILPPARPTDKALRLPLQ 251
                        |.:|            :|..|.|....:.|...::.:.||....|...|..:.
  Fly   250 ------------DEVL------------RVSAKLGTGVSEVLERVIETVPPPQVQRDSDFRALIF 290

  Fly   252 D------------VYKIGG----------IGTVPVGRVET-GVLKPGTVVVFAPANITTEVKSVE 293
            |            :|.:.|          :.|..|..|:: .||:|....|  |.....:|..:.
  Fly   291 DSWFDKYRGALNLIYVLNGKLEQNQDIQSLATKKVYSVKSISVLRPAECPV--PDVSAGQVGLIA 353

  Fly   294 MHHEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKANPP 334
            .:....:|::.||.:  ::||.:|.      .||..:...|
  Fly   354 CNMRNSKESIVGDTI--HLKNQAVA------AAGSYRPQQP 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	86/366 (23%)
waw	NP_001027089.1	PRK05433	94..695	CDD:235462	86/366 (23%)
		LepA	100..277	CDD:206677	58/239 (24%)
		EF4_II	285..370	CDD:293900	16/88 (18%)
		EF4_III	386..461	CDD:293917	1/1 (100%)
		lepA_C	502..581	CDD:239680
		LepA_C	589..695	CDD:283959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840