Protein Alignment eEF1alpha1 and eEF2

DIOPT Version :9

• Sequence 1: NP_001286321.1
• Gene: eEF1alpha1 / 36271
• FlyBaseID: FBgn0284245
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 586
• Identity: 121/586 - (20%)
• Similarity: 185/586 - (31%)
• Gaps: 247/586 - (42%)

  Fly     1 MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKA 65
            |.|::...|:.||.|||.||||.|..|:.|.|.|          ...:.|:..|     .|..|.
  Fly    13 MDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGII----------AGAKAGETRF-----TDTRKD 62

  Fly    66 ERERGITID---IALWKFETAK------------------YYVTIIDAPGHRDFIKNMITGTSQA 109
            |:||.|||.   |::: ||..:                  :.:.:||:|||.||...:.......
  Fly    63 EQERCITIKSTAISMY-FEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVT 126

  Fly   110 DCAVLIVAAGTGEFEAGISKNGQT------------------REHALLAFTLGVKQL-------I 149
            |.|:::|     :..:|:....:|                  .:.|||...|..::|       :
  Fly   127 DGALVVV-----DCVSGVCVQTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIV 186

  Fly   150 VGVN----------------KMDSSE----------------PPYSEARYEEIKKEVSSYIKKIG 182
            ..||                ::|.|:                ..:||...|:.|.:|...:.::
  Fly   187 ENVNVIIATYNDDGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFKIDVVKLMNRL- 250

  Fly   183 YNPAAVAFVPISGWHGDNMLEPSTNMPWFKGWKVERKEGNADGKT-----LIDAL----DAILPP 238
                         | |:|.....|     |.|   :|:..||.|.     ::|.:    |||:.
  Fly   251 -------------W-GENFFNAKT-----KKW---QKQKEADNKRSFCMYILDPIYKVFDAIMN- 292

  Fly   239 ARPTDKALRLPLQDVYKIGGIGT-----------------------------VPVGRVETGVLKP 274
                           ||...|||                             :|.|.   .:|:
  Fly   293 ---------------YKKEEIGTLLEKIGVTLKHEDKDKDGKALLKTVMRTWLPAGE---ALLQ- 338

  Fly   275 GTVVVFAPANITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKANPPKGAAD 339
             .:.:..|:.:..:...:||    |.|....|.....||:.........|:   ||..|......
  Fly   339 -MIAIHLPSPVVAQKYRMEM----LYEGPHDDEAAIAVKSCDPDGPLMMYI---SKMVPTSDKGR 395

  Fly   340 FTAQVIVLNHPGQIANG---------YTPVLDCHTAHIACKFAEIKEKVDRRS----GKTTEENP 391
            |.|...|.  .|::|.|         |||          .|..::.||..:|:    |:..|
  Fly   396 FYAFGRVF--AGKVATGQKCRIMGPNYTP----------GKKEDLYEKAIQRTILMMGRYVE--- 445

  Fly   392 KFIKSGDAAIVNLVPSKPLC----VEAFQEFPPLGRFAVRDMRQTVAVGVIKAVNFKDASGGKVT 452
                     .:..|||..:|    |:.|                .|..|.|  ..||||...||.
  Fly   446 ---------AIEDVPSGNICGLVGVDQF----------------LVKTGTI--TTFKDAHNMKVM 483

  Fly   453 K 453
            |
  Fly   484 K 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	121/586 (21%)
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	121/586 (21%)
		EF2	20..236	CDD:206672	51/236 (22%)
		EF2_snRNP_like_II	380..474	CDD:293901	28/138 (20%)
		EF2_snRNP_III	489..560	CDD:293918
		aeEF2_snRNP_like_IV	560..732	CDD:238839
		eEF2_snRNP_like_C	728..807	CDD:239763

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464627
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840