Protein Alignment eEF1alpha1 and EIF2S3B

DIOPT Version :9

• Sequence 1: NP_001286321.1
• Gene: eEF1alpha1 / 36271
• FlyBaseID: FBgn0284245
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_001344663.1
• Gene: EIF2S3B / 255308
• HGNCID: 43863
• Length: 472
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 101/501 - (20%)
• Similarity: 156/501 - (31%)
• Gaps: 201/501 - (40%)

  Fly     8 INIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGIT 72
            |||..||||..||||    ::....|:  .|:                      :.|.|.||.||
Human    42 INIGTIGHVAHGKST----VVKAISGV--HTV----------------------RFKNELERNIT 78

  Fly    73 IDIALWKFETAKYY----------------------------------------VTIIDAPGHRD 97
            |.:.   :..||.|                                        |:.:|.|||..
Human    79 IKLG---YANAKIYQLDDPSCPRPECYRSCGSSMPDEFPTDIPGTKGNFRLVRHVSFVDCPGHDI 140

  Fly    98 FIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSSEPPY 162
            .:..|:.|.:..|.|:|::|....      ....||.||......:.:|.:::..||:|..:...
Human   141 LMATMLNGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKHILILQNKIDLVKERQ 199

  Fly   163 SEARYEEIKKEVSSYIKKIGYNPAAVAFVPISGWHGDNMLEPSTNMPWFKGWKVERKEGNADGKT 227
            ::.:||:|...|...:.:      ....:|||                            |..|.
Human   200 AKEQYEQILAFVQGTVAE------GAPIIPIS----------------------------AQLKY 230

  Fly   228 LIDALDAIL------PPARPTDKALRLPLQ--DVYKIGG-----IGTVPVGRVETGVLKPGTVVV 279
            .|:.:...:      ||...|.:...:.::  ||.|.|.     .|.|..|.:..||||.|....
Human   231 NIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQETE 295

  Fly   280 FAPA-------------NITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKA 331
            ..|.             :|.:::.|:...|..||.|.||                 |.:...:|.
Human   296 VRPGIVSKDSEGKLMCKSIFSKIVSLFAEHNDLQYAAPG-----------------GLIGVGTKI 343

  Fly   332 NPPKGAADFTAQVIVLNHPGQI--ANGYTPVLDCHTAHIACKFAEIKEK---VDRRSGKTTEENP 391
            :|....||        ...|||  |.|..|.:          |.|::..   :.|..|..||.:.
Human   344 DPTLCRAD--------RMVGQILGAVGALPEI----------FTELEISYFLLRRLLGVRTEGDK 390

  Fly   392 KFIK-----SGDAAIVN-------------------LVPSKPLCVE 413
            |..|     ..:..:||                   :|.:.|:|.|
Human   391 KAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTE 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	101/501 (20%)
EIF2S3B	NP_001344663.1	PTZ00327	13..466	CDD:240362	101/501 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910