Protein Alignment eEF1alpha1 and eef-1A.2

DIOPT Version :9

• Sequence 1: NP_001286321.1
• Gene: eEF1alpha1 / 36271
• FlyBaseID: FBgn0284245
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_509323.1
• Gene: eef-1A.2 / 181044
• WormBaseID: WBGene00001169
• Length: 463
• Species: Caenorhabditis elegans
• Alignment Length: 463
• Identity: 382/463 - (82%)
• Similarity: 419/463 - (90%)
• Gaps: 0/463 - (0%)

  Fly     1 MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKA 65
            |||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Worm     1 MGKEKVHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKA 65

  Fly    66 ERERGITIDIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKN 130
            |||||||||||||||||||||:|||||||||||||||||||||||||||:||.||||||||||||
 Worm    66 ERERGITIDIALWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVACGTGEFEAGISKN 130

  Fly   131 GQTREHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKKIGYNPAAVAFVPISG 195
            ||||||||||.|||||||||..|||||:|||:||||:.||..|||.:||||||||.||.||||||
 Worm   131 GQTREHALLAQTLGVKQLIVACNKMDSTEPPFSEARFTEITNEVSGFIKKIGYNPKAVPFVPISG 195

  Fly   196 WHGDNMLEPSTNMPWFKGWKVERKEGNADGKTLIDALDAILPPARPTDKALRLPLQDVYKIGGIG 260
            ::||||||.|:||||||||.||||||||.||||::|||:|:||.||||:.|||||||||||||||
 Worm   196 FNGDNMLEVSSNMPWFKGWAVERKEGNASGKTLLEALDSIIPPQRPTDRPLRLPLQDVYKIGGIG 260

  Fly   261 TVPVGRVETGVLKPGTVVVFAPANITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYV 325
            ||||||||||::|||.||.|||.|:||||||||||||:|.||||||||||||||||||::|||.|
 Worm   261 TVPVGRVETGIIKPGMVVTFAPQNVTTEVKSVEMHHESLPEAVPGDNVGFNVKNVSVKDIRRGSV 325

  Fly   326 AGDSKANPPKGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFAEIKEKVDRRSGKTTEEN 390
            ..|||.:|.|.|..|.||||::||||||:||||||||||||||||||.|:|||||||:||..|:.
 Worm   326 CSDSKQDPAKEARTFHAQVIIMNHPGQISNGYTPVLDCHTAHIACKFNELKEKVDRRTGKKVEDF 390

  Fly   391 PKFIKSGDAAIVNLVPSKPLCVEAFQEFPPLGRFAVRDMRQTVAVGVIKAVNFKDASGGKVTKAA 455
            |||:|||||.||.|:|:||||||:|.::.||||||||||||||||||||:|...|.|.|||||:|
 Worm   391 PKFLKSGDAGIVELIPTKPLCVESFTDYAPLGRFAVRDMRQTVAVGVIKSVEKSDGSSGKVTKSA 455

  Fly   456 EKATKGKK 463
            :||...||
 Worm   456 QKAAPKKK 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	378/455 (83%)
eef-1A.2	NP_509323.1	PTZ00141	1..461	CDD:185474	380/459 (83%)
		EF1_alpha	9..239	CDD:206670	203/229 (89%)
		EF1_alpha_II	242..332	CDD:293894	74/89 (83%)
		EF1_alpha_III	335..438	CDD:294004	78/102 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159510
Domainoid	1	1.000	423	1.000	Domainoid score	I314
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68181
Inparanoid	1	1.050	786	1.000	Inparanoid score	I261
Isobase	1	0.950	-	0	Normalized mean entropy	S32
OMA	1	1.010	-	-		QHG62187
OrthoDB	1	1.010	-	-		D1150082at2759
OrthoFinder	1	1.000	-	-		FOG0000314
OrthoInspector	1	1.000	-	-		otm14723
orthoMCL	1	0.900	-	-		OOG6_100227
Panther	1	1.100	-	-	O	PTHR23115
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2502
SonicParanoid	1	1.000	-	-		X149
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.890