DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ERp60 and tmx4

DIOPT Version :9

Sequence 1:	NP_725084.2	Gene:	ERp60 / 36270	FlyBaseID:	FBgn0033663	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_001025330.1	Gene:	tmx4 / 792311	ZFINID:	ZDB-GENE-050706-155	Length:	277	Species:	Danio rerio

Alignment Length:	116	Identity:	35/116 - (30%)
Similarity:	53/116 - (45%)	Gaps:	10/116 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 DAPVKVAVAKNFDDLVINNGKDTLIEFYAPWCGHCKKLSPIYEELAEKLQDEDVAIVKMDATAN- 426
            ||...|.||.....|::..  :.:|:||||||..|:.|...:|.|..:.....:::.::|.|..
Zfish    27 DASNVVTVADANWTLILQG--EWMIKFYAPWCPACQHLQADWENLGRQSDSLGISVGRVDVTQQP 89

  Fly   427 DVPPEFNVRGFPTLFWLPKDAKNKPV-SYNGGREVDDFLKYIA--KEATTE 474
            .:...|.|...||:|    .|||... .|...|.::|...|:.  |.||.|
Zfish    90 GLSGRFLVTTLPTIF----HAKNGDFRKYVSSRTIEDIQAYVVHRKWATVE 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	35/116 (30%)
		PDI_a_PDIR	23..126	CDD:239295
		PDI_b_ERp57	133..235	CDD:239367
		PDI_b'_ERp72_ERp57	239..345	CDD:239371
		PDI_a_PDI_a'_C	365..467	CDD:239293	28/103 (27%)
tmx4	NP_001025330.1	Thioredoxin_like	29..129	CDD:294274	29/105 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591999
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840