Protein Alignment ERp60 and Tmx1

DIOPT Version :10

• Sequence 1: NP_725084.2
• Gene: ERp60 / 36270
• FlyBaseID: FBgn0033663
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_082615.1
• Gene: Tmx1 / 72736
• MGIID: 1919986
• Length: 278
• Species: Mus musculus
• Alignment Length: 278
• Identity: 61/278 - (21%)
• Similarity: 117/278 - (42%)
• Gaps: 68/278 - (24%)

  Fly     8 VLLLGFIAISSGAEQDVLELGDDDFATTLKQHETTLVMFYAPWCGHCKRLKPEYAKAAEIVKDDD 72
            ||||..:..:.|...:|..|.|::: |:|.:.| .::.||||||..|:.|:||:...||  ..:|
Mouse    15 VLLLWAVPGAHGRRNNVRVLTDENW-TSLLEGE-WMIEFYAPWCPACQNLQPEWESFAE--WGED 75

  Fly    73 PPIKLAKVDCTEAGKET--CSKYSVSGYPTLKIFRQDEVSQDYNGPREASGIAKY---------- 125
            ..:|:||||.||   :|  ..::.::..|::...:..|..: |.|||.......:
Mouse    76 LEVKVAKVDVTE---QTGLSGRFIITALPSIYHCKDGEFRR-YVGPRTKKDFINFVSDKEWKNIE 136

  Fly   126 -MRAQVGPASKTVRTVA---ELKKFLDTKD---------------------TTLFG--------Y 157
             :.:..||:|..:..::   :|..::.|..                     |.|.|        :
Mouse   137 PISSWFGPSSVLMTMMSALFQLSVYIRTSHSYFVHDLGIPAWGSYLVFAFATVLSGLLLGLCMIF 201

  Fly   158 FSD--SDSKLAKIFLKFADKNREKYRFGHSSEKEVLDKQGETDKIVLIRAPHLSNKFESSSIKFE 220
            .:|  ..||..|...::|.|...::    |...:.::::.|.|:         .:..|..:...|
Mouse   202 VADCLCPSKRRKPQQQYAKKTSPEF----SQPLKKVEEEQEADE---------EDVSEEEAEDRE 253

  Fly   221 GSSESDLSTFVKENFHGL 238
            |:|::...:.:::...||
Mouse   254 GASKATSQSSIRQRCVGL 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	56/263 (21%)
Tmx1	NP_082615.1	PDI_a_TMX	30..129	CDD:239292	33/106 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..278		11/68 (16%)