| Sequence 1: | NP_725084.2 | Gene: | ERp60 / 36270 | FlyBaseID: | FBgn0033663 | Length: | 489 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_006840.2 | Gene: | PDIA2 / 64714 | HGNCID: | 14180 | Length: | 525 | Species: | Homo sapiens |
| Alignment Length: | 477 | Identity: | 152/477 - (31%) |
|---|---|---|---|
| Similarity: | 232/477 - (48%) | Gaps: | 56/477 - (11%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 21 EQDVLELGDDDFATTLKQHETTLVMFYAPWCGHCKRLKPEYAKAAEIVKDDDPPIKLAKVDCTEA 85
Fly 86 GKETCSKYSVSGYPTLKIFRQDEVS--QDYNGPREASGIAKYMRAQVGPASKTVRTVAELKKFLD 148
Fly 149 TKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKEVLDKQGET-DKIVLIRAPHLSNKF 212
Fly 213 ESSSIKFEGSSE-----SDLSTFVKENFHGLVGH-RTQDSVKDFQ-----------NPLITAYYS 260
Fly 261 VDYQKNPKGTNYWRNRVL-----KVAKEFVGQINFAIAS-KDDFQHELNEYGYDFVGDKPVVLAR 319
Fly 320 DEKNLKYALKD--EFSVENLQDFVEKLLANELEPYIKSEPIPESND-APVKVAVAKNFDDLVINN 381
Fly 382 GKDTLIEFYAPWCGHCKKLSPIYEELAEKLQD-EDVAIVKMDATANDVPPEFNVRGFPTLFWLPK 445
Fly 446 DAKNKPVSYNGGREVDDFLKYI 467 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ERp60 | NP_725084.2 | ER_PDI_fam | 23..479 | CDD:273457 | 151/475 (32%) |
| PDI_a_PDIR | 23..126 | CDD:239295 | 45/104 (43%) | ||
| PDI_b_ERp57 | 133..235 | CDD:239367 | 23/107 (21%) | ||
| PDI_b'_ERp72_ERp57 | 239..345 | CDD:239371 | 25/125 (20%) | ||
| PDI_a_PDI_a'_C | 365..467 | CDD:239293 | 46/102 (45%) | ||
| PDIA2 | NP_006840.2 | ER_PDI_fam | 42..497 | CDD:273457 | 151/476 (32%) |
| Thioredoxin_like | 62..151 | CDD:294274 | 42/89 (47%) | ||
| PDI_b_family | 157..254 | CDD:239279 | 23/103 (22%) | ||
| PDI_b'_family | 259..368 | CDD:239280 | 25/125 (20%) | ||
| PDI_a_PDI_a'_C | 389..491 | CDD:239293 | 46/102 (45%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 492..525 | 152/477 (32%) | |||
| Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 | 522..525 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165156372 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0190 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG53639 | |
| OrthoDB | 1 | 1.010 | - | - | D222522at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000292 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X241 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 7 | 6.760 | |||||