Protein Alignment ERp60 and Tmx4

DIOPT Version :10

• Sequence 1: NP_725084.2
• Gene: ERp60 / 36270
• FlyBaseID: FBgn0033663
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_083424.1
• Gene: Tmx4 / 52837
• MGIID: 106558
• Length: 335
• Species: Mus musculus
• Alignment Length: 336
• Identity: 75/336 - (22%)
• Similarity: 107/336 - (31%)
• Gaps: 117/336 - (34%)

  Fly     8 VLLLGFIAISS--GAEQDVLELGDDDFATTLKQHETTLVM-------FYAPWCGHCKRLKPE--- 60
            |||..::|.::  |.||..|. .::.....:.....||||       ||||||..|::...|
Mouse     9 VLLAAWLAAAAAEGLEQAALP-AEESRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWET 72

  Fly    61 YAKAAEIVKDDDPPIKLAKVD-CTEAGKETCSKYSVSGYPTLKIFRQDEVSQDYNGPREASGIAK 124
            :||..|.::     |.:.||| ..|.|  ...::.|:..|.. ...:|.:.:.|.||.....:..
Mouse    73 FAKNGETLQ-----ISVGKVDVIQEPG--LSGRFFVTTLPAF-FHAKDGIFRRYRGPGIYEDLQN 129

  Fly   125 Y-----------MRAQVGPASKTVRTVAEL-----------KKFLDTKD-------------TTL 154
            |           :.....|||.|:..:|.|           ..|..|..             |.:
Mouse   130 YILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVTLGIPAWCSYVFFVIATLV 194

  Fly   155 FGYF----------------------------------------------SDSDSKLAKIFLKFA 173
            ||.|                                              .||:.:..|..|  .
Mouse   195 FGLFMGLILVVISECFCVPLPRASSERCEQEQSTGEAQGAEQLQDAEEEKDDSNEEENKDSL--V 257

  Fly   174 DKNREKYRFGHSSEKEVLDKQGETDKIVLIRAPHLSNKFESSSIKFEGSSESDLSTFVKENFHGL 238
            |...||...|...|.|   :..|.|.:..|.|...|:..|.:.:| |||        |.....|.
Mouse   258 DDEEEKEDIGDEDEGE---EDEEEDNLAGIMAEERSDTNERAVVK-EGS--------VSPKEDGA 310

  Fly   239 VGHRTQDSVKD 249
            ....|||.|:|
Mouse   311 HPADTQDVVED 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	68/319 (21%)
Tmx4	NP_083424.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	33..133	CDD:469754	28/107 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	222..316		22/107 (21%)