Protein Alignment ERp60 and CG13671

DIOPT Version :10

• Sequence 1: NP_725084.2
• Gene: ERp60 / 36270
• FlyBaseID: FBgn0033663
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_648202.1
• Gene: CG13671 / 38932
• FlyBaseID: FBgn0035867
• Length: 698
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 109/633 - (17%)
• Similarity: 210/633 - (33%)
• Gaps: 201/633 - (31%)

  Fly     8 VLLLGFIAISSGAEQDVLELGDDDFATTLK--------------QHETTLVMFYAPWCGHCKRLK 58
            :|.|..:|:|. |:.|.......|.|..::              :.|.:|:.:|..|....::.:
  Fly     4 ILSLLLLALSI-AQLDASRSATSDQAPIVECPGRSVPQLRAEASESEISLLFYYVSWASEARQAR 67

  Fly    59 PEYAKAAEIVKDDDPPIKLAKVDCTEAGKETCSKY-----SVSG-------YPTLKI-FRQDEVS 110
            ..|...|...::..   ....:||... :..||:.     .|:|       :|||.: :.|.::.
  Fly    68 LVYNGLAHYYQEYG---FFGAIDCWHL-QCNCSRTLMPAPGVAGAGGYPDKWPTLIVRYGQKQLL 128

  Fly   111 QDYNGPREASGIAKYMRAQVGPASK--TVRTVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFA 173
            | |.|......:|::|...:.|..:  :.:.:|.::|.   .|..:.|.....|.|...::|...
  Fly   129 Q-YQGSWSFEDLARFMNNLLQPLDRAHSSQDLAAIRKH---SDAVVLGLLDSPDDKAYNLYLAAG 189

  Fly   174 --------DKN-REKYRFGHSSEKEVLDKQGETDKIVLI-------------------------- 203
                    ::| |....||:|:.|.:...:.:..:.|:|
  Fly   190 LRWLELDPERNIRFTVYFGNSARKMLKSSEAKLPQFVVIDSRNGVHTFNGTSGVWKTIDILRWVR 254

  Fly   204 ---------------------RAPHL--------SNKFESSSI---------------------K 218
                                 :|.|:        .|::..:|:                     |
  Fly   255 STLKNMSLFSNGYGTPMTIAMKARHVPVLAMGVRMNQYHHASVMGEEMAYAQKKQSEGCEDYWKK 319

  Fly   219 FEGSSE---SDLSTFVKENFHGLVGHRTQDSVKDFQNPLITA--YYSVD-----------YQKNP 267
            |:..||   |.|:...||.|..  |.:|:.....:.....|.  ||.::           :|.:|
  Fly   320 FDKQSEDISSSLNQVPKELFGD--GEQTRTCYPAWSKNKTTLKNYYRINRYLNHLWRQYSHQNHP 382

  Fly   268 K--------------------------------------GTNYWRNRVLKVA-KEFVGQINFAIA 293
            .                                      |...|::...:.| ...:|.:.|...
  Fly   383 SYRNVPHLLRLHSRNLCLAHSQHGTPAIKIGIAKMVTKYGQLIWQHSTERAAHNRSLGVVIFDSV 447

  Fly   294 SKDDFQHELNEYGYDFVGDKPVVLARD--EKNLKYALKDE--FSVENLQDFVEKLLANELEPYIK 354
            ...|:.|:|   |......:..|...|  |::| |.:..:  ||...|:||:.:.       |.:
  Fly   448 KYRDYLHQL---GIQQTHQQVQVFILDAAEESL-YVMPQQHTFSYVALKDFIRQF-------YAR 501

  Fly   355 SEPIPESND-APVKVAVAKNFDDLV----INNGKDTLIEF-YAPWCGHCKKLSPIYEELAEKLQD 413
            :.|....|. |.::...::.::..:    |.....|.:.| :.|.|.....||..:.:::..|..
  Fly   502 TLPRTHKNALAMMESGFSRKYNRQMLLQAIQRPNVTNVVFMHRPDCALSAVLSQAFLQVSALLGS 566

  Fly   414 EDVAIVKMDATANDVPPEFNVRGFPTLFWLPKDAKNKPVSYNGGREVD 461
            .:|..|:.|:.|||:|.|..:...|:|...|:....:.|.:.....:|
  Fly   567 PEVHFVRFDSQANDLPWELAMPTTPSLIVFPQAKSAESVVFPTDVRID 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	104/618 (17%)
CG13671	NP_648202.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	<46..>97	CDD:469754	9/54 (17%)
		Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	<565..622	CDD:469754	13/50 (26%)