DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ERp60 and CG8993

DIOPT Version :9

Sequence 1:	NP_725084.2	Gene:	ERp60 / 36270	FlyBaseID:	FBgn0033663	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_647716.1	Gene:	CG8993 / 38301	FlyBaseID:	FBgn0035334	Length:	142	Species:	Drosophila melanogaster

Alignment Length:	131	Identity:	37/131 - (28%)
Similarity:	59/131 - (45%)	Gaps:	5/131 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RLAGVLLLGFIAISSGAEQDVLELGDDDFATTLK-QHETTLVMFYAPWCGHCKRLKPEYAKAAEI 67
            |||....:..:::|:..::.......:||...:| ..:..:|.|:|.||..||.|.|   :...|
  Fly    15 RLASGQQIRMLSVSAPRQEIFKVQSAEDFDKKVKNSQQPVIVDFFATWCNPCKLLTP---RIESI 76

  Fly    68 VKDDDPPIKLAKVDCTEAGKETCSKYSVSGYPTLKIFRQDEVSQDYNGPREASGIAKYMRAQVGP 132
            |.:....|||||||..| ..|....|.|:..|.|.:.:..:..|...|.::...|..::.|.|..
  Fly    77 VGEQAGSIKLAKVDIDE-HSELALDYDVAAVPVLVVLQNGKEVQRMVGLQDEDKIRAWVAAAVKQ 140

  Fly   133 A 133
            |
  Fly   141 A 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	33/112 (29%)
		PDI_a_PDIR	23..126	CDD:239295	30/103 (29%)
		PDI_b_ERp57	133..235	CDD:239367	1/1 (100%)
		PDI_b'_ERp72_ERp57	239..345	CDD:239371
		PDI_a_PDI_a'_C	365..467	CDD:239293
CG8993	NP_647716.1	Thioredoxin_like	39..138	CDD:294274	31/102 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910