Protein Alignment ERp60 and CaBP1

DIOPT Version :10

• Sequence 1: NP_725084.2
• Gene: ERp60 / 36270
• FlyBaseID: FBgn0033663
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_609792.1
• Gene: CaBP1 / 34976
• FlyBaseID: FBgn0025678
• Length: 433
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 116/505 - (22%)
• Similarity: 167/505 - (33%)
• Gaps: 236/505 - (46%)

  Fly     2 MWRLAGVLLLGFIAISSGA----EQDVLELGDDDF-ATTLKQHETTLVMFYAPWCGHCKRLKPEY 61
            |.:||.:|||.|:..|..|    ...|:||...:| ...||.....:|.|||||||||:.|.|||
  Fly     1 MRQLASILLLAFVVGSVSAFYSPSDGVVELTPSNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEY 65

  Fly    62 AKAAEIVKDDDPPIKLAKVDCTEAGKETCSKYSVSGYPTLKIFRQDEVS-QDYNGPREASGIAKY 125
            .|.|:.:|.   .:|:..|: .:|......::.|.|:||:|||..::.| .||||.|.|..||:
  Fly    66 KKLAKALKG---VVKVGSVN-ADADSTLSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKAIAE- 125

  Fly   126 MRAQVGPASKTVRTVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKEV 190
                        ..:||:||                     |:                   :.|
  Fly   126 ------------AALAEVKK---------------------KV-------------------QGV 138

  Fly   191 LDKQGETDKIVLIRAPHLSNKFESSSIKFEGSSESDLSTFVKENFHGLVGHRTQDSVKDFQNPLI 255
            |...|                  .||....|||.
  Fly   139 LGGGG------------------GSSSGGSGSSS------------------------------- 154

  Fly   256 TAYYSVDYQKNPKGTNYWRNRVLKVAKEFVGQINFAIASKDDFQHELNEYGYDFVGDKPVVLARD 320
                                                                   ||..:.|..|
  Fly   155 -------------------------------------------------------GDDVIELTED 164

  Fly   321 EKNLKYALKDEFSVENLQDFVEKLLANELEPYIKSEPIPESNDAPVKVAVAKNFDDLVINNGKDT 385
                                                                |||.||:|:....
  Fly   165 ----------------------------------------------------NFDKLVLNSDDIW 177

  Fly   386 LIEFYAPWCGHCKKLSPIYEELAEKLQDEDVAIVKMDATAN-DVPPEFNVRGFPTLFWLPKDAK- 448
            |:||:||||||||.|:|.:.:.|::|:.: |.:..:||||: ....|:||||:||:.:.|..:|
  Fly   178 LVEFFAPWCGHCKNLAPEWAKAAKELKGK-VKLGALDATAHQSKAAEYNVRGYPTIKFFPAGSKR 241

  Fly   449 -NKPVSYNGGREVDDFL-----KYIAKEATTEL------KGFDRS--GKP 484
             :....|:|||...|.:     |::|.....||      ..|:.:  |||
  Fly   242 ASDAQEYDGGRTASDIVSWASDKHVANVPAPELIEIINESTFETACEGKP 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	103/471 (22%)
CaBP1	NP_609792.1	PDI_a_P5	26..119	CDD:239299	38/96 (40%)
		PDI_a_P5	157..262	CDD:239299	42/157 (27%)
		P5_C	271..400	CDD:239281	6/21 (29%)