Protein Alignment ERp60 and prtp

DIOPT Version :9

• Sequence 1: NP_725084.2
• Gene: ERp60 / 36270
• FlyBaseID: FBgn0033663
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001188583.1
• Gene: prtp / 32124
• FlyBaseID: FBgn0030329
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 504
• Identity: 120/504 - (23%)
• Similarity: 199/504 - (39%)
• Gaps: 144/504 - (28%)

  Fly     5 LAGVLLLGFIAISSGAEQD---------VLELGDDDFATTLKQHETTLVMFYAPWCGHCKRLKPE 60
            :.|:||...:.|:..::::         .:||..:.|.|.: ......|.|:|||||||||::|.
  Fly    11 VCGLLLSPLLPITRASQEEDTGKQDKQFTVELDPETFDTAI-AGGNVFVKFFAPWCGHCKRIQPL 74

  Fly    61 YAKAAEIVKDDDPPIKLAKVDCTEAGKETCSKYSVSGYPTLKIFR-QDEVSQDYNGPREASGIAK 124
            :.:.|||:..|:|.:.:||||||: .:..|:.:.|:|||||::|: .:|.|..:.|.|:...|..
  Fly    75 WEQLAEIMNVDNPKVIIAKVDCTK-HQGLCATHQVTGYPTLRLFKLGEEESVKFKGTRDLPAITD 138

  Fly   125 YMRAQVGPASKTVRTVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKE 189
            ::                                                 |:|
  Fly   139 FI-------------------------------------------------NKE----------- 143

  Fly   190 VLDKQGETDKIVLIRAPHLSNKFESSSIKFEGSSESDLSTFVKENFHGLVGHRTQDSVKD-FQNP 253
                         :.||                :|:||....:|....|...:..|..:| |...
  Fly   144 -------------LSAP----------------AEADLGEVKREQVENLNIGKVVDLTEDTFAKH 179

  Fly   254 LITAYYSVDY---------QKNPKGTNYWRNRVLKVAKEFVGQINFAIASKDDFQHELNEYGYDF 309
            :.|..:.|.:         :..|.    |.:    :|||.:.:....|:..|..|.......::.
  Fly   180 VSTGNHFVKFFAPWCSHCQRLAPT----WED----LAKELIKEPTVTISKIDCTQFRSICQDFEV 236

  Fly   310 VGDKPVVLARDEKNL-KYALKDEFSVENLQDFVEKLLANELE--------PYIKSEPIPESNDA- 364
            .|...::...|.|.: ||:...:.|  .|:.:|||::...||        ..:..|.:....||
  Fly   237 KGYPTLLWIEDGKKIEKYSGARDLS--TLKTYVEKMVGVPLEKTAGEAGDEKVVIEEVAGEEDAA 299

  Fly   365 ----PVKVAVAKNFDDLVINNGKDTLIEFYAPWCGHCKKLSPIYEELAEKLQ--DEDVAIVKMDA 423
                |.::.....||..:...  ...|:|||||||||:||.|.:|:||.:..  ...|.|.|:|.
  Fly   300 KKLTPQQLTGEDEFDQAIAEG--VAFIKFYAPWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDC 362

  Fly   424 TA---NDVPPEFNVRGFPTLFWLPKDAKNKPVSYNGGREVDDFLKYIAK 469
            ||   ..|..:..|.|:|||| |.|:.:.:. .|.|.|.:.:...|:.|
  Fly   363 TAPENKQVCIDQQVEGYPTLF-LYKNGQRQN-EYEGSRSLPELQAYLKK 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	116/486 (24%)
		PDI_a_PDIR	23..126	CDD:239295	40/112 (36%)
		PDI_b_ERp57	133..235	CDD:239367	8/101 (8%)
		PDI_b'_ERp72_ERp57	239..345	CDD:239371	23/116 (20%)
		PDI_a_PDI_a'_C	365..467	CDD:239293	37/106 (35%)
prtp	NP_001188583.1	PDI_a_ERp46	38..140	CDD:239303	40/103 (39%)
		ER_PDI_fam	39..409	CDD:273457	115/474 (24%)
		PDI_a_ERp46	167..267	CDD:239303	20/109 (18%)
		PDI_a_ERp46	303..407	CDD:239303	37/107 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463722
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840