Protein Alignment ERp60 and erp-44.3

DIOPT Version :9

• Sequence 1: NP_725084.2
• Gene: ERp60 / 36270
• FlyBaseID: FBgn0033663
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_501357.3
• Gene: erp-44.3 / 185676
• WormBaseID: WBGene00018358
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 507
• Identity: 95/507 - (18%)
• Similarity: 166/507 - (32%)
• Gaps: 161/507 - (31%)

  Fly     9 LLLGF-----IAISSGAEQDVLELGDDDFATTLKQHETTLVMFYAPWCGHCKRLKPEYAKAAEIV 68
            |||||     |:::...| .:.....|:.   ::....|.|.|.|.||...::|...:::||...
 Worm    31 LLLGFGITFLISVNCNLE-SITSTNHDEI---IQNSRLTFVAFTASWCPFSRKLMSSFSQAAADY 91

  Fly    69 KDDDPPIKL--AKVDCTEAGKETCSKYSVSGYPTLKIFRQDEVSQDYNGPREASGIAKYMRAQVG 131
            :...|..|.  ..|||. |.....:|||::.:||:|:|....:..:|.|.|:..|:.:|:.....
 Worm    92 QAKYPDRKTVWGNVDCM-AEDYLMNKYSITKFPTMKVFFYGYMMTEYRGSRQVKGLIEYIEKMEN 155

  Fly   132 PAS----KTVRTVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKEVLD 192
            .:|    ....::.:.:.::..:..||..:|.........|....|        ..||.
 Worm   156 TSSLVNLNEAESLTQWQNYVIPQKGTLILWFPRGSPPFELILKAIA--------LIHSQ------ 206

  Fly   193 KQGETDKIVLIRAPHLSN--KFESSSI----------KFEGSSES--DLSTFVKENFHGLVGHRT 243
                    :::..|...|  |.|...:          :||||..:  ::..::|:...|:|...|
 Worm   207 --------LVVVVPISENLLKHEDHQLWFSLDGEHVERFEGSVSNFKEIVEWIKKKSAGMVRELT 263

  Fly   244 QDSVKDFQNPLITAYYSVDYQKNPKGTNYWRNRVLKVAKEFVGQINFAIASKDDFQHELNEYGYD 308
            .:::::
 Worm   264 FENMEE----------------------------------------------------------- 269

  Fly   309 FVGDKPVVLARDEKNLKYALKDEFSVENLQDFVEKLLANELEPYIKSEPIPESNDAPVKVAVAKN 373
                    :..|.|.|...|:.:..:|..:.|| ..:..||:.....:..|...|..|..||.::
 Worm   270 --------MVEDGKPLLILLRKKDDIETEKQFV-TTIRRELDQDTLLKLAPVMADGKVLTAVLRH 325

  Fly   374 FDDLVINNGKDTL---------IEFYAPWCG--------------------HCKKLSPIYEELAE 409
            |     |.|.|.|         ..|.:||.|                    |.:||.....||.:
 Worm   326 F-----NKGLDDLPFLLIDQFTHSFPSPWKGNEIFAEGNIKQFVADLFNDNHHRKLHEKLNELIQ 385

  Fly   410 KLQDEDVAIVKMDATANDVPPEFNVRGFPTLFWLPKDAKNKPVS--YNGGRE 459
            |:..|...|.|..:......|...:....::|     .|.||.|  |:..:|
 Worm   386 KIVTETEEIEKQASEEKVEKPTEKLEKHESVF-----NKLKPASTRYSFAKE 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	88/488 (18%)
		PDI_a_PDIR	23..126	CDD:239295	27/104 (26%)
		PDI_b_ERp57	133..235	CDD:239367	17/119 (14%)
		PDI_b'_ERp72_ERp57	239..345	CDD:239371	9/105 (9%)
		PDI_a_PDI_a'_C	365..467	CDD:239293	29/126 (23%)
erp-44.3	NP_501357.3	Thioredoxin_like	45..150	CDD:381987	28/109 (26%)
		Thioredoxin_like	259..369	CDD:381987	25/182 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910