DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ERp60 and erp27

DIOPT Version :9

Sequence 1:	NP_725084.2	Gene:	ERp60 / 36270	FlyBaseID:	FBgn0033663	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	XP_017209875.1	Gene:	erp27 / 100004902	-ID:	-	Length:	252	Species:	Danio rerio

Alignment Length:	224	Identity:	54/224 - (24%)
Similarity:	91/224 - (40%)	Gaps:	26/224 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 AELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKEVLDKQG-ETDKIVLIR 204
            |..:.|:|:.|..:.|:|.|..::....||. |.|..::......|||||..|.| .:|.|.:.|
Zfish    30 AAAQAFIDSADVAVIGFFQDESARGYSEFLD-AVKQMQELPVALCSEKEVWAKYGISSDTISVFR 93

  Fly   205 APHLSNKFESSSIKFEGSSESDLSTFVKENFHGLVGHRTQDSVKDFQNPLITAYYSV-------- 261
            ...|..:....|...:..|...|...:..|...:..:....:|..||:.:.|....|
Zfish    94 KADLHQEHLKLSEAKKVDSAGLLRFLIINNISYVTEYNQASAVGIFQSSVKTHVLLVCAGGRSAS 158

  Fly   262 DYQKNPKGTNYWRNRVLKVAKEFVGQINFAIAS-KDDFQHELNEYGYDFVGDKPVV----LARDE 321
            |.|:     ..:|:    :|.::.|::.|.:.: .|.....:.||......|.|.|    :..|:
Zfish   159 DPQQ-----KLFRD----LAVKYAGKMLFILVNGADKSNSRVLEYFSLKSADLPRVGLYDVTLDQ 214

  Fly   322 KNLKYALKDEFSVENLQDFVEKLLANELE 350
            |.|..|  .|.:.|.:|:|.:..|..||:
Zfish   215 KWLMAA--GEITTERVQNFCDSFLDGELQ 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	54/224 (24%)
		PDI_a_PDIR	23..126	CDD:239295
		PDI_b_ERp57	133..235	CDD:239367	25/94 (27%)
		PDI_b'_ERp72_ERp57	239..345	CDD:239371	25/118 (21%)
		PDI_a_PDI_a'_C	365..467	CDD:239293
erp27	XP_017209875.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D462118at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010