Protein Alignment cuff and RAI1

DIOPT Version :10

• Sequence 1: NP_610709.1
• Gene: cuff / 36269
• FlyBaseID: FBgn0260932
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_011268.1
• Gene: RAI1 / 852646
• SGDID: S000003215
• Length: 387
• Species: Saccharomyces cerevisiae
• Alignment Length: 262
• Identity: 39/262 - (14%)
• Similarity: 89/262 - (33%)
• Gaps: 74/262 - (28%)

  Fly    66 RYKDSPPKLEKKPNIFLDNMLQYIESSSYMYVMVRNNQQAQLNANIVCTSEVLELMMCAPYEKKT 130
            ::||.....|.:.:  |..:|:.||||       ..::..::||:|:....:...::...::..:
Yeast    65 KFKDYYKDFEDRCS--LRGLLETIESS-------ERHKGKKINADIITFRGIARKLISCAFDSPS 120

  Fly   131 --GWSLGVTRYRNTMYICRIDVEQPDPIDQ----------DNLKRAMQEFWLRNLRTHCVFENGI 183
              ...|.:..:...::|    .|.|:.::.          .|:.:.:..|......|.....|.:
Yeast   121 FNTVDLRIVSFNGQLFI----KEVPEAVNAAKASSATEAGRNINQDLNVFTGYKFETLATLSNPL 181

  Fly   184 KMHQHN--QSSEEHLRFHG------------------------VFSFDLNGNRVLFDSPVLAEMP 222
            :.....  :...:.:..||                        :|.|..||
Yeast   182 QYTPREVIEKRTKRIVSHGDEYISVVRTGVGNCKLILGAEVDCIFDFKENG-------------- 232

  Fly   223 STTLNGSALSWVDLQIRPMFMSRLDWPEHNRTEALKWWVKCFLLGIESLYIARRDENAHVHNIEK 287
                ..:...:.:|:......:..|..:..| :..:.|::|||:||..:....:|:    |.:.|
Yeast   233 ----RDNLKHYAELKCTQQVANISDTHKFER-KLFRTWLQCFLVGIPRIIYGFKDD----HYVLK 288

  Fly   288 TL 289
            |:
Yeast   289 TV 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cuff	NP_610709.1	DUF6454	<32..>69	CDD:437887	0/2 (0%)
		RAI1	<257..284	CDD:462550	7/26 (27%)
RAI1	NP_011268.1	RAI1	222..289	CDD:462550	15/89 (17%)