Protein Alignment cuff and Dxo

DIOPT Version :10

• Sequence 1: NP_610709.1
• Gene: cuff / 36269
• FlyBaseID: FBgn0260932
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_997662.1
• Gene: Dxo / 361799
• RGDID: 1303267
• Length: 397
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 89/378 - (23%)
• Similarity: 151/378 - (39%)
• Gaps: 47/378 - (12%)

  Fly    23 FPTITKPVSNGWFAWSPIGQFEPNSQKVPYVVVPPSIKFP---ISLR--YKDSPPKLEKKPNIFL 82
            ||...:|...|.|:.....|:..:::.:.| ..||.|..|   ..||  |.|.....:::....|
  Rat    40 FPFYRRPSELGCFSLDAQRQYHGDARALRY-YSPPPINGPGPDFDLRDGYPDRYQPRDEEVRERL 103

  Fly    83 DNMLQYIESSSYMYVMVRNNQ----QAQLNANIVCTSEVLELMMCAPYEKKTGWSLGVTRYRNTM 143
            |::|:        :|:...||    ...|....|.....|..::..|||::.||.|..:|::.|:
  Rat   104 DHLLR--------WVLEHRNQLEGGPGWLAGATVTWRGHLTKLLTTPYERQEGWQLAASRFQGTL 160

  Fly   144 YICRIDVEQPDPIDQDNLKRAMQEFWLRNLRTHCVFENGIKMHQH----------NQSSE--EHL 196
            |:.  :||.|    ....:|..:...||.|     ...|.|..|:          :.|.|  .::
  Rat   161 YLS--EVETP----AARAQRLARPPLLREL-----MYMGYKFEQYMCADKPGGSPDPSGEVNTNV 214

  Fly   197 RFHGVFSFDLNGNRVLFDSPVLAEMPSTTLNGSALSWVDLQIRPMFMSRLDWPEHNRTEALKWWV 261
            .|..|....|..:.:||...|....|..........:|:|:......|...|....|.:.||||.
  Rat   215 AFCSVLRSRLGNHPLLFSGEVDCLNPQAPCTQPPSCYVELKTSKEMHSPGQWRSFYRHKLLKWWA 279

  Fly   262 KCFLLGIESLYIARRDENAHVHNIEKTLVRDLWKSCEKD---WSPTVCANFMIYLLNCISQVMAP 323
            :.||.|:..:....|:....|.:::.....:::::...|   |:|:||.||....|: .:|....
  Rat   280 QSFLPGVPYVVAGFRNPEGFVCSLKTFPTMEMFENVRNDQEGWNPSVCMNFCAAFLS-FAQSTVV 343

  Fly   324 IDCPSTVYLFQFDASQGTVSYKGLRGRNQYTFVSDWFRMMLDDHTNDMCKTPN 376
            .|.|..|:||.::.. |.|:....|.. .|.|:..|:...:......:.|||:
  Rat   344 QDDPRLVHLFSWEPG-GPVTVSVHRDA-PYAFLPSWYVEAMTQDLPSLSKTPS 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cuff	NP_610709.1	DUF6454	<32..>69	CDD:437887	11/41 (27%)
		RAI1	<257..284	CDD:462550	9/26 (35%)
Dxo	NP_997662.1	RAI1	235..300	CDD:462550	15/64 (23%)