DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13185 and Pla1a

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	NP_620237.1	Gene:	Pla1a / 85311	RGDID:	621261	Length:	456	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	60/287 - (20%)
Similarity:	109/287 - (37%)	Gaps:	76/287 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   865 WQTLREKLQKLQMQLDKSINISFAFIPGSLVNCISNGDWVLLDEINLASAETLE---CLSTILEP 926
            |.:|      |.:.:.:|.|:.    |.:...|..      ....||.....|:   .|.|..:|
  Rat    13 WGSL------LWLSIGRSGNVP----PTTQPKCTD------FQSANLLRGTNLKVQFLLFTPSDP 61

  Fly   927 EGSVVLLERGDFTPVKRHPDFRIFACMNPNTDIGKKDL-----PVGIRNRFTEFFVDELTTDADL 986
            ....::.|..|.    |:.:|        |..:|.|.:     .:|.:..:...|:..|...||.
  Rat    62 GCGQLVEEDSDI----RNSEF--------NASLGTKLIIHGFRALGTKPSWINKFIRALLRAADA 114

  Fly   987 SLLVSDYL-ANTGIQRKSVHNIVQL----YKSLRKLSELQLNDGLGNRPVYSLRTLCRSLRICAR 1046
            :::..|:: .:||:...:|.|:|:|    .:.|.||.||.:::.              |:.|...
  Rat   115 NVIAVDWVYGSTGMYFSAVENVVKLSLEISRFLSKLLELGVSES--------------SIHIIGV 165

  Fly  1047 NL---CGSIERNLYESFCLSFLTQLDPNSHHVVLLLIQNALLSN----VKAI------LSKQLPQ 1098
            :|   .|.:..:.|:. .|..:|.|||.........::..|.|.    |:||      |..::|
  Rat   166 SLGAHVGGMVGHFYKG-QLGRITGLDPAGPEYTRASLEERLDSGDALFVEAIHTDTDNLGIRIP- 228

  Fly  1099 LGENYLDFEGYWIQPGNLEPQPCTHYI 1125
              ..::|   |::..|..:| .|..:|
  Rat   229 --VGHVD---YFVNGGQDQP-GCPAFI 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	60/287 (21%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359	16/92 (17%)
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265
		PHA03151	4856..5060	CDD:177546
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
Pla1a	NP_620237.1	Lipase	14..336	CDD:278576	59/286 (21%)
Pla1a	NP_620237.1	Pancreat_lipase_like	49..332	CDD:238363	51/235 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910