DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and gap43

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	NP_001072212.1	Gene:	gap43 / 779658	XenbaseID:	XB-GENE-5899285	Length:	210	Species:	Xenopus tropicalis

Alignment Length:	240	Identity:	58/240 - (24%)
Similarity:	97/240 - (40%)	Gaps:	43/240 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  4671 MQDVEKPEEDDSGESEEEEDLNKEMGETEEGAEKLDDQIWGDDEEEKPEEEQEPDMNEEDQGKGS 4735
            |:..::.|:::..:.:.|:|.||...:..:.|.|:.....|....:|.:
Frog     5 MRRTKQVEKNEDADQKIEQDGNKPEDKAHKAATKIQASFRGHIIRKKLK---------------- 53

  Fly  4736 KDEKDAHNDLDTKNDAAKEDGKDEHEKDGLDATNEPSGE----DKRKEQAKDIDDMKDPEMDEEQ 4796
            .|:||.::|...:|   .:||..:.||:. ..|.||:.:    ||::..:..:.|.|.....|:.
Frog    54 VDKKDDNSDEAVEN---HKDGATKTEKEA-PKTEEPTADGPLGDKKEAVSSPVGDKKPEPSSEKN 114

  Fly  4797 TNAMHNELEEPPEPEEMDLGDMNNVDEGHDDQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEH 4861
            .:....|.:.|.|.|....|...|...|...|              .||..:.|:.|||. .|..
Frog   115 QDPPSEEKQAPAETESTTKGSTENSPGGEATQ--------------AKEEPKKADVPEAT-QDAA 164

  Fly  4862 DANEEGDPQSDGSDSEEDEAGTEAKP---AEEDHGEGEEATPEDE 4903
            ...|:|..:|...|.::||. .|.||   |::|....|||.|:.|
Frog   165 SEQEQGKAESSQEDIKKDEV-EETKPSESAQQDEAVSEEAKPDQE 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	58/240 (24%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265	23/64 (36%)
		PHA03151	4856..5060	CDD:177546	17/51 (33%)
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
gap43	NP_001072212.1	Neuromodulin_N	3..32	CDD:371147	6/26 (23%)
		IQ	31..>49	CDD:197470	3/17 (18%)
		Neuromodulin	67..210	CDD:369001	44/162 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910