DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and RBM23

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	XP_024305408.1	Gene:	RBM23 / 55147	HGNCID:	20155	Length:	515	Species:	Homo sapiens

Alignment Length:	194	Identity:	34/194 - (17%)
Similarity:	64/194 - (32%)	Gaps:	54/194 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  4925 DSPEDSKEEKEEKREEKPEEHSQSKDKASKEENVQSMPETDQSSSADQVQQPQDPDIKQDQKLDE 4989
            ::|...:|::::::|.|.:..|.:....|...|     ||..||:
Human    59 EAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGN-----ETSGSST-------------------- 98

  Fly  4990 QETGEEKDGVGQAENDADDGGHQGVAETQETVSQEDRKNERQTQEKRKQGRTNEERSLGEAEQNK 5054
                     :|:.........|.         ...|||..|.....|.:.|.:..||.|...:::
Human    99 ---------IGETSKKKRSRSHN---------KSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHR 145

  Fly  5055 LKQLK----TIDQLKDSKESDDAEQEKPEPMDQTEAEEYQHVKEP----KNSDKTTLDNATEEQ 5110
            .:...    :..:.:|.:..|......| |:  .....|.|.|.|    |:..:..:||.:.|:
Human   146 SRSWDRRHGSESRSRDHRREDRVHYRSP-PL--ATGYRYGHSKSPHFREKSPVREPVDNLSPEE 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	34/194 (18%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265
		PHA03151	4856..5060	CDD:177546	22/138 (16%)
		MttA_Hcf106	<5046..5166	CDD:294511	14/73 (19%)
		vWA_midasin	5261..5526	CDD:238737
RBM23	XP_024305408.1	RRM	143..514	CDD:330708	12/67 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910