Protein Alignment CG13185 and AgaP_AGAP002959

DIOPT Version :9

• Sequence 1: NP_001097279.2
• Gene: CG13185 / 36268
• FlyBaseID: FBgn0033661
• Length: 5526
• Species: Drosophila melanogaster
• Sequence 2: XP_001237407.3
• Gene: AgaP_AGAP002959 / 4577309
• VectorBaseID: AGAP002959
• Length: 913
• Species: Anopheles gambiae
• Alignment Length: 1068
• Identity: 185/1068 - (17%)
• Similarity: 323/1068 - (30%)
• Gaps: 361/1068 - (33%)

  Fly  2546 EDFLSDVILNSGNLNSLTLIKRQAVALKVLLDGYTEGKIPQKLLASLFHEMEKLKLDQRNPQKLI 2610
            ||..:|..:.|.::.....|..:....|...|.|.|       |..:.|:|..|...:::.:
Mosquito    41 EDDDNDESIESKHIKEYIEILTKIAGDKYNYDNYAE-------LLEVAHQMNDLDKIRQSAE--- 95

  Fly  2611 RHFLYMLYESSAIGDLELRHLYLQPWLSKDTAFQELSQNLYNCLQKRSNTDTGTLANLPWNRKLI 2675
              ....:|..|.  ::.||.|.::..|:  |..:|:.:                      ..||.
Mosquito    96 --IFAAMYPLSP--EIWLRWLKIESSLA--TTDEEVEK----------------------VEKLF 132

  Fly  2676 PR-LRDYSTAESNSELNPLNL---SALLLARLVVDIIPVSSVTTVQQMNALQYSQALCKKQVTEK 2736
            .| |.||.:||...|...|.:   |..:..|:...:||...:.|::            .:.:.|.
Mosquito   133 QRALSDYYSAEVALEFAALAMKTDSKTIAERIWKTLIPTYGLHTMK------------GRSIFEA 185

  Fly  2737 YANHLLANFSSFLEVLHTSLLEDLETADLDLPQYAHLVTRFHWFNRILATAQQKLLYNNELHVPL 2801
            |.                   ||..|.|.|.|..         |||:..      :|..||.:||
Mosquito   186 YR-------------------EDTLTKDGDSPAS---------FNRLAR------IYEQELKIPL 216

  Fly  2802 --MHKLVLHFQWL-EKHLLVPLIEL----------TAKSGCARMLTIQDRTLKIKKYIEETRRPL 2853
              |....:.::.| ||:..| |.:|          .||....|||..:.....::.:..:.|..|
Mosquito   217 RNMEDSYIEYKLLCEKYKDV-LTDLDAEKFERRYKQAKEALQRMLPHETALAALEAHCHQERADL 280

  Fly  2854 NVTCKIYSKQFTQFQPYYQDQQIQRHIELDDLEKLLSVVPSYGNLELSSWLKRWLLLQTDDANKW 2918
                  |.|.....|....|.::|...|....|..|                        |...|
Mosquito   281 ------YRKYIADCQTLLDDDEVQILYERMVTECCL------------------------DGAVW 315

  Fly  2919 RSFLRKHTNGFQPKAFEISGSLRNETLQSHLQKLQTTLKEAQENSAE-IEMDLELDLNSIKTLLE 2982
            ..::|                           .|.....:|::|:|. :....||||  :...|.
Mosquito   316 HEYVR---------------------------YLHRCPPDAEDNTASPVFRQTELDL--VNRALR 351

  Fly  2983 AETEESESYIHPDGI----PTNTPKLLIAALRE---------------LFMERLL---------- 3018
            ..|..:|.|:....|    .|.|.|:.|..:.|               :::|.|.
Mosquito   352 NCTWSAELYVEKMRIVERQATPTSKMTILKIMEDVASAGLQTPEASVKVWLEYLTYLRRVTDFAS 416

  Fly  3019 ---TGTLRDDFDEQVNPL------YADQLLTL-----------------NSNLWHCLKTLESANR 3057
               ...||.:||...|.|      .||....:                 ..:||:  ..:.|::.
Mosquito   417 EKERDILRANFDLAWNQLGRTWGVLADPQCKILQYWGRLEYEALGEPNKGRDLWY--SVMASSDN 479

  Fly  3058 TEITNAWIELKNEVNELQNYDEFAVLLEKIGGGYKGLRSYQRQYRNSVQCYQLENLSTRLDCVQG 3122
            :.....||             ||..:..|     :|..:.::.||.|:....|::
Mosquito   480 SSRVGLWI-------------EFIEMEAK-----RGPEAARKLYRKSITTAGLDD---------- 516

  Fly  3123 PSEEGSTDISSQFCYRGPALSGVILSLICQPNGQLRSVPLSELLEWRSALQQTRHLIWENSQLLT 3187
                                                              .:|....|    |..
Mosquito   517 --------------------------------------------------PETLAAAW----LRF 527

  Fly  3188 SRYSGEVNNLLQAKENARQLLKELEYVRKLSEK--EQKANQGFENCAKELEKMIEKLEKEENNNA 3250
            .|.:|.:..|:..:|.....::  :|.:.:|:.  ..:|.:|     |..|.|.....|:.:.:|
Mosquito   528 ERCNGSLEQLISCQELCNATIE--KYYKTISKNGPSNRATKG-----KRPEAMGTTAHKDSDASA 585

  Fly  3251 SMTKDFEVSLTNALVGAIELCLLTNTPLIDPVEKNRLKNEYIAEDIDCLSTLTTAYDFMKIAMKY 3315
            :..:...:..........:....||..|.|.|.:.  :.|:....|..|.:.:..:|..|.....
Mosquito   586 AKRQASSMDGAGGSPPGKKKVKRTNDNLSDTVGER--QEEFKTPAIPPLHSSSKNHDHSKPEPSK 648

  Fly  3316 RHFGEEIYSELELRLRTALQRQ---QQLSQKLALRSEKCLYASL-VQDITHFLHSNGDCESLYKL 3376
            .....:|.||.:.:......||   ..||.::.....:.::..| ::.|.....|:|
Mosquito   649 PQTVIDIDSESDAKAGGDQSRQVFVSNLSFEVTETDIREIFPDLAIESIELVASSSG-------- 705

  Fly  3377 FQLIHSEWENFQGLHVATSAQLKSSIEV----LGKLDLWLANAQRFVHHTLSRYSAYYQDFVEPI 3437
                  :...|..:.:|::.::..::..    |....::::|..|  ..|...:...|....||.
Mosquito   706 ------KSRGFGYMQLASAEEVPKALSFDRRPLNGRPVFISNVAR--DKTTRPHQFKYSSSFEPN 762

  Fly  3438 KCSVNQLRF--GLESLKVIFTRVQQAGSVSQAEQMQQTIGDIVQFPSQHPLVIRNSRLYGLLAEL 3500
            |..:..|.|  |.|.|:.:|   :..||:....        ||.|.|            |....|
Mosquito   763 KLFIKGLPFNLGQEELRRLF---EPFGSIKDIR--------IVCFRS------------GKSKGL 804

  Fly  3501 PHSEYEYFRLLKAKLSELSNYIALGRVI 3528
            .:.|||.....|..:.::..::..|..|
Mosquito   805 AYLEYETETSAKNAVLKMDQHVIDGFTI 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	185/1068 (17%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265
		PHA03151	4856..5060	CDD:177546
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
AgaP_AGAP002959	XP_001237407.3	RRM_SF	671..740	CDD:302621	9/82 (11%)
		RRM_SF	760..840	CDD:302621	23/96 (24%)
		Lsm_interact	895..913	CDD:283133

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910