DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and Fkbp39

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	NP_524364.2	Gene:	Fkbp39 / 41860	FlyBaseID:	FBgn0013269	Length:	357	Species:	Drosophila melanogaster

Alignment Length:	272	Identity:	64/272 - (23%)
Similarity:	105/272 - (38%)	Gaps:	79/272 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  4815 LGDMNNVDEGHDDQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEHDANEEGDPQSDGSDSEED 4879
            ||.::::|...|:.|:|.|.||..:..|:|.:.:        .:|:.|.||.|  :.|..|:::|
  Fly    84 LGYLHDIDSEDDEDDDQMTIENLLNSKAIKNSKK--------SEDDEDENESG--EEDEEDTDDD 138

  Fly  4880 EAGTEAKPAEEDHGEGEEATPEDEKDEAETQKRGELEDEDDSKPEDSPED--------------- 4929
            ....|...:..::||.|:   :|:.|| :.::.|| |||.||...::.|:
  Fly   139 SQIIEEYESFLENGEEED---DDDVDE-DNEESGE-EDEQDSDDSEAEEEQPKAKVAKLSPGASA 198

  Fly  4930 SKEEKEEKREEKPEEHSQSKDKASKEENVQSMPETDQSSSADQVQQPQDPD---IKQDQKLDEQE 4991
            .|..||:....|.||..|.:.|..|.|..:..|:..:.:.    |||...|   |....|:.:|.
  Fly   199 KKSGKEQNGVAKKEEAKQQQKKKEKPEAKKEQPKAKEPAK----QQPASKDPRTITGGVKIVDQV 259

  Fly  4992 TGEEKDGVGQAENDADDGGHQGVAETQETVSQEDRKNERQTQEKRKQGRTNEERSLGEAEQNKLK 5056
            .|:                                      .|:.|||:......:|..:.|.
  Fly   260 VGK--------------------------------------GEEAKQGKRVSVYYIGRLQSNN-- 284

  Fly  5057 QLKTIDQLKDSK 5068
              ||.|.|...|
  Fly   285 --KTFDSLLKGK 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	64/272 (24%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265	21/76 (28%)
		PHA03151	4856..5060	CDD:177546	48/221 (22%)
		MttA_Hcf106	<5046..5166	CDD:294511	7/23 (30%)
		vWA_midasin	5261..5526	CDD:238737
Fkbp39	NP_524364.2	FKBP_C	262..354	CDD:278674	11/75 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910