Protein Alignment CG13185 and psip1b

DIOPT Version :9

• Sequence 1: NP_001097279.2
• Gene: CG13185 / 36268
• FlyBaseID: FBgn0033661
• Length: 5526
• Species: Drosophila melanogaster
• Sequence 2: XP_021325735.1
• Gene: psip1b / 407619
• ZFINID: ZDB-GENE-030131-3273
• Length: 1564
• Species: Danio rerio
• Alignment Length: 1579
• Identity: 318/1579 - (20%)
• Similarity: 586/1579 - (37%)
• Gaps: 422/1579 - (26%)

  Fly  4040 DKGKGLRNYNK---IKYLHTERQQFVASEKLLEKFAIQEEFLSDNTLLQRLDKHFRTARHVV--K 4099
            |.|.|||...|   :|.|...|.::...:|  :|...|.|          :.|..::|:..|  .
Zfish    93 DPGVGLRGQKKAALVKRLSESRLKWKNKKK--KKAENQTE----------VKKPPKSAKDPVSNS 145

  Fly  4100 ETLGQVPY-----GELITELDDLLASQLERCEHLRSLNVDRSKERPQQKQEAKQILQQKR----K 4155
            ::....|:     .|.:|..||      :..|...:.:.|.|.:....|:...:::..::    |
Zfish   146 DSKAATPHKRETKSESVTLKDD------KNTETRPTRSRDSSAKTSTDKRRTDKVVPARKMTSVK 204

  Fly  4156 ALTDLFKMLHRLGANYKTGLLELSLRNEFEDFQLPPYSIRSMLPRLHPTAQQLDEHLDLYYMKSV 4220
            .:|              ||...|            |.|:  :|.|....|:.|..|     .|.|
Zfish   205 TIT--------------TGWRRL------------PSSV--ILARRMDAAKTLSAH-----RKHV 236

  Fly  4221 FKLKLLQNI--MLTPLSELGPPNIERIKGFAVDLFLLVQQQREHLSGSTKELHELRNSLDS-LRK 4282
            ...|::...  .:..::...|..|.|.....:       :..:.::.....|...|...|| ::.
Zfish   237 LNRKIISTAKKRIDAVNHRKPSRITRSTADPI-------EATDDVTAKPLALKRKRKQNDSEVKG 294

  Fly  4283 LAEI-IPQADINPS-----------TLNFVKSADIAMEIKQHLRQI-------HYVLKQWKLLLS 4328
            .|.| ||..||:.|           |....||.|...|:|::..|.       ..:.||
Zfish   295 DAPISIPATDISASSTPTGSKRRRLTEPEKKSKDDEKELKENEAQSKEKNEVEQKIEKQ------ 353

  Fly  4329 CAPSSFIEES---ENRLLVRKISLAQSELHSLCIQILNSSQELL--NELNNANLEYLSSEKCVTY 4388
                :.:|:|   :|:::.:|                |.:::::  ||..|...:...||
Zfish   354 ----NEVEKSNADKNKMMEKK----------------NQAEKIVAENETENKGAKKKESE----- 393

  Fly  4389 QKSYAEIQENIKKTLELLRT----GQNDYLPLAQPIVELLDSVQLKNHTE-IAPEAIDLANADTE 4448
             ||.||.:::.||..:.:.|    .:|......:|         .||.:| ...|.|:...:::|
Zfish   394 -KSDAEKEKSEKKETKKIETERKEARNSEAESKEP---------CKNDSEKKEAERIETRKSESE 448

  Fly  4449 LANIAHSVLMS----------------MQKIYKHHVKTDEV----NQNGEAKEQDEESKEALQ-E 4492
                   ||::                |::..|:..|..|.    ::..|.::.:.|.|||.: |
Zfish   449 -------VLVAKNKESEKRETRKSESEMKEARKNESKKQEARKSESEKRETRKSESEMKEARKNE 506

  Fly  4493 QHLKKCLTGELTSDWQQLSLPRVLGKLSNVLLVLKHSHFEGKD--KLLCVRRAIGLLPVLEQYQL 4555
            ..:|:....|        |..|...|..:.::..:.:..|.|:  |....||.
Zfish   507 SEMKEARKSE--------SEKRETRKSESEMIEARKNESEMKEARKSESERRE------------ 551

  Fly  4556 LADYLLLQQLATHKVSAKMLSIVLTVFVEIGSKGFCVPPDLMQDEEGQSKQESKNGEGFGLEDGT 4620
                 .....|..|.:.|..|.:..:...         .:..:..:..|:.|:||.|....|.|.
Zfish   552 -----TKNSEAEIKEARKNESEIEAIRSN---------SEKRETRKSDSEMEAKNNESEKREAGK 602

  Fly  4621 GENDASDKIESEDQLDDAKRPEDRKDEGDKQEPDCKE----EKGIEMSDDFDAKMQDVEKPEED- 4680
            .|::..:..::|.:..:|::.|.||.|.|.:|...||    |..|:::.|.|::.::..|.|.:
Zfish   603 SESEMKEARKNESEKKEARKRETRKSESDMKEAKRKETRKSESEIKVAKDNDSEKRETTKNESEI 667

  Fly  4681 ----------DSGESEEE-EDLNKEMGETEEG--------------AEKLDDQI--WGDDEEEKP 4718
                      ::|:||.| ::..|...|.||.              |.|.:.:|  ..|::.||.
Zfish   668 EAKNKESEKREAGKSESEIKEARKNESEKEEARKRETRKSESDMKEARKNESEIKVAKDNDSEKR 732

  Fly  4719 EEEQ-----EPDMNEEDQGKGSKDEKDAHNDLDT--------KNDAAKEDGKDEHEKDGLDATNE 4770
            |..|     |...||.::.:..|.|.:......|        ||::.||..:||.||
Zfish   733 ETRQNEFEIETKNNESEKRETRKSESEMKEARKTDSEIIEAKKNESEKESKRDESEK-------- 789

  Fly  4771 PSGEDKRKEQAKDIDDMKDPEMDEEQTNAMHNELE-----------------------EPPEPEE 4812
                   :|..|:..:||:...:|.:..|:.||.|                       |..|.::
Zfish   790 -------RETRKNESEMKEARKNESEKRAIRNESEKRETKSQSEIKESEKREARNIESEKKEAKK 847

  Fly  4813 MDLGDMNNVDEGHDDQDEQPTDEN---------PFDIDAMKENMQPAEEPEADGDDEHDANEEGD 4868
            :| .:|....:...::.|....|:         ....::.|:.::.:|..:.:.:.:.:...|.:
Zfish   848 ID-SEMKQARKNESEKKEARKSESEKKEAERVETRKTESEKKEVRKSESEKKEAERKLERKSESE 911

  Fly  4869 -PQSDGSDSEEDEA---GTEAKPAEEDHGEGEEA-TPEDEKDEA---ETQKRGELEDEDDSKPED 4925
             .::..|:||..||   .:|.|.|.....|.:|| ..|.||.||   |::||.....|.:.|...
Zfish   912 RKEAKKSESENKEARGNESEKKGARRSESEKKEARQSESEKKEARRSESEKRENRRSESEKKEAR 976

  Fly  4926 SPEDSKEE---KEEKRE------EKPEEHSQSKDKASKEENVQSMPETDQSSSADQVQQPQDPDI 4981
            ..|..|.|   :.||||      ||.|...:..:|...........||.:|.|  :.::|:....
Zfish   977 RNESEKRETRSESEKRETRRNESEKREPRWRESEKKETRRRESEKKETRRSES--EKKEPRSESK 1039

  Fly  4982 KQDQKLDEQETGE----------------EKDGVGQAENDADDGGHQGVAETQETVSQEDRKNER 5030
            |::.:..|.|..|                ||.....:|:|..:      |:..|:..:|.|::|.
Zfish  1040 KKEARRSESEKKEARRSEFEKKEARRSEFEKKEARMSESDKKE------AKRNESEKKEARRSEF 1098

  Fly  5031 QTQEKRKQGRTNEERSLGEAEQNKLKQLKTIDQLKDSKESDDA-------------EQEKPEPMD 5082
            :.:|.|:.....:|..:.|:|:.:..:.:..:..::..|..||             |.||.|...
Zfish  1099 EKKEARRSEFEKKEARMSESEKARRSEFEKKEARRNESEKKDARRNESEKKEARRNESEKKEARS 1163

  Fly  5083 QTEAEEYQHVKEPKNSDKTTLDNATEEQSKKIQHQEDEP-PNEEEIEAENVD-ELMEAEEPAVDP 5145
            ::|.:|.:..:..||..:.  :.:.:::.::|:.::.|. .|:.|.||...| ||.||.
Zfish  1164 ESEKKEARRNESEKNEGRR--NESEKKEERRIESEKKEARKNKSEKEARRSDSELKEAR------ 1220

  Fly  5146 EDDAELEQLGAEKTEQKSDKPSKTEKSKEQLETPEGMEIEGEVVLTMTVPRSSE-TTAHSNSEIL 5209
            ..::||::....::|:|.::..::||.:.:....|......:..|.....:.|| ..|..|..:.
Zfish  1221 RKESELKEARRNESEKKEERRIESEKKEARKNKSEKEARRSDSELKEARRKESELKEARRNESVK 1285

  Fly  5210 LDKSSHAEDLSSAEQ-----------IELRQQYQKQLTTFRVAQPEHEDYETWQGISNRMTQNAR 5263
            .|....|.:.:.||:           :|.|::...:....:...|...| ||.:....|..:..:
Zfish  1286 SDAEKDAVEKNKAEKNKLPEKRKEINVEERRETMTKPKQTKSCAPVSSD-ETQEEKKPRDEERCK 1349

  Fly  5264 ELCEQLRLILEPTK--CTRLKGDYRTGRRINMKKIIPYIASQFRKDKIWLRRTKPAQRDYKIT-- 5324
            .|.|:.:.:|:..:  .|..:|...:|.....:...|      ||::.. |..:||:.:.|.|
Zfish  1350 ILAEKRQSVLKSLQGLVTSTRGKTPSGSEQTTETKEP------RKERNH-RLKQPAEDEKKDTEK 1407

  Fly  5325 -------------------------IAIDDS--KSMHHNNSKTLTLEAISLVSQALTLLESGRLS 5362
                                     :::.||  ..:|.:...::|||... ||:.|:.|:  .||
Zfish  1408 RKEQEKRNTEQQISSSKEEERRAHSLSVTDSLLYRLHGDIRISMTLENPD-VSKCLSALD--ELS 1469

  Fly  5363 IVSFGEAPQIILNHTEQFD 5381
            .|..  :.:.|.||:|..|
Zfish  1470 NVPV--SSRNIQNHSELID 1486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	318/1579 (20%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265	23/84 (27%)
		PHA03151	4856..5060	CDD:177546	56/236 (24%)
		MttA_Hcf106	<5046..5166	CDD:294511	28/134 (21%)
		vWA_midasin	5261..5526	CDD:238737	32/152 (21%)
psip1b	XP_021325735.1	HDGF_related	14..93	CDD:99895	318/1579 (20%)
		Neuromodulin_N	<221..921	CDD:331332	154/809 (19%)
		Neuromodulin_N	<586..1321	CDD:331332	167/766 (22%)
		LEDGF	1440..1534	CDD:314400	16/52 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910