DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and zranb2

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	XP_017211949.1	Gene:	zranb2 / 406716	ZFINID:	ZDB-GENE-040426-2743	Length:	324	Species:	Danio rerio

Alignment Length:	293	Identity:	58/293 - (19%)
Similarity:	109/293 - (37%)	Gaps:	63/293 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  4754 EDGKDEHEKD-GLDATNEPSGED------KRKEQAKDIDDMKDPEMDE---------EQTNAMHN 4802
            |.||...||. ||.:.|:...:.      .|:.:....:..|..:::|         |:.|.::|
Zfish    51 EIGKTLAEKSRGLFSANDWQCKTCGNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENLVYN 115

  Fly  4803 ELEEPPEPEEMDLGDMNNVDEGHDDQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEHDANEEG 4867
            |.|| .:.|..:.|.:.....|...:|....:| |..:|             .|.::|.|.:|:|
Zfish   116 EREE-SDGEYDEFGRIKKKFRGKTKKDSDKKEE-PKKVD-------------QDDEEEDDDDEDG 165

  Fly  4868 DPQS---DGSDSEEDEAGTEAKPAEEDHGEGEEATPEDEKDEAETQKRGELEDEDDSKPEDSPED 4929
            |...   |..|.::|:                   .:|::|:|:..|. :|:|.|:.|...|...
Zfish   166 DLSKYKLDDDDEDDDD-------------------DDDDEDDADLSKY-DLDDGDEKKGSHSGSS 210

  Fly  4930 SKEEKEEKREEKPEEHSQSKDKASKEENVQSMPETDQSS-----SADQVQQPQDPDIK----QDQ 4985
            ....:......:....|:|:..:|.....:|..::..||     ||...::.:.|...    |.:
Zfish   211 RSSSRSSSSSSRSRSRSRSRSSSSSRSRSRSRSKSRSSSRSGKGSASSKKRSRSPSSSPEGGQKR 275

  Fly  4986 KLDEQETGEEKDGVGQAENDADDGGHQGVAETQ 5018
            ......:|..|....::.:....|...||.:|:
Zfish   276 SRSRSSSGGRKKRRARSHSSERFGVTHGVLDTR 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	58/293 (20%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265	15/79 (19%)
		PHA03151	4856..5060	CDD:177546	34/175 (19%)
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
zranb2	XP_017211949.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910