DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and Yp1

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	NP_001285071.1	Gene:	Yp1 / 31939	FlyBaseID:	FBgn0004045	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	481	Identity:	82/481 - (17%)
Similarity:	154/481 - (32%)	Gaps:	179/481 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly  3030 VNPLYADQLLTLNSNLWHCLKTL----------ESANRTEITNAWIELKNEVNELQNYDEFAV-L 3083
            :||:....||.       ||...          .|.|:....:.|:. .:::..:...|:|.: .
  Fly     1 MNPMRVLSLLA-------CLAVAALAKPNGRMDNSVNQALKPSQWLS-GSQLEAIPALDDFTIER 57

  Fly  3084 LEKIGGGYKGLRSYQRQYRNSVQCYQLENLSTRLDCVQGPSEEGSTDISSQFCYRGPALSGVILS 3148
            ||.:        :.:|......|.|.|..:...::....||.                    |..
  Fly    58 LENM--------NLERGAELLQQVYHLSQIHHNVEPNYVPSG--------------------IQV 94

  Fly  3149 LICQPNGQLRSVPLSELLEWRSALQQTRHLIWENSQLLTSRYSGEVNNLLQAKENARQLLKEL-- 3211
            .:.:|||.....||:|:::   .|:|.::...:...::       |..|.|..|..::..::|
  Fly    95 YVPKPNGDKTVAPLNEMIQ---RLKQKQNFGEDEVTII-------VTGLPQTSETVKKATRKLVQ 149

  Fly  3212 EYVRKLSEKEQK-----ANQGFENCAKELEKMIEKLEKEENNNASMTKDFEVSLTNALVGAIELC 3271
            .|:::.:.::|:     .||.:::         :..|:.:|...|..:|:...:.||...:.::.
  Fly   150 AYMQRYNLQQQRQHGKNGNQDYQD---------QSNEQRKNQRTSSEEDYSEEVKNAKTQSGDII 205

  Fly  3272 LLTNTPLIDPVEKNRLKNEYIAEDIDCLSTLTTAYDFMKIAMKYRHFGEEIYSELELRLRTALQR 3336
                  :||...|......|...||:            |...|...:..::.:||::.
  Fly   206 ------VIDLGSKLNTYERYAMLDIE------------KTGAKIGKWIVQMVNELDMP------- 245

  Fly  3337 QQQLSQKLALRSEKCLYASLVQDITHFLHSNGDCESLYKLFQLIHSEWENFQGLHVATSAQLKSS 3401
                                                    |..||...:|. |.|||.:|
  Fly   246 ----------------------------------------FDTIHLIGQNV-GAHVAGAA----- 264

  Fly  3402 IEVLGKLDLWLANAQRFVH---HTLSRYSAYYQDFVEPIKC---SVNQL----RFGLESLKVIFT 3456
                         ||.|..   |.|.|.:.     ::|.|.   |.|.|    |...|.:..|.|
  Fly   265 -------------AQEFTRLTGHKLRRVTG-----LDPSKIVAKSKNTLTGLARGDAEFVDAIHT 311

  Fly  3457 RVQQAGSVSQAEQMQQTIGDIVQFPS 3482
            .|...|:..::       ||:..:|:
  Fly   312 SVYGMGTPIRS-------GDVDFYPN 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	82/481 (17%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265
		PHA03151	4856..5060	CDD:177546
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
Yp1	NP_001285071.1	Abhydrolase	183..406	CDD:304388	43/244 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910