Protein Alignment CG13185 and GABRA6

DIOPT Version :9

• Sequence 1: NP_001097279.2
• Gene: CG13185 / 36268
• FlyBaseID: FBgn0033661
• Length: 5526
• Species: Drosophila melanogaster
• Sequence 2: NP_000802.2
• Gene: GABRA6 / 2559
• HGNCID: 4080
• Length: 453
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 108/544 - (19%)
• Similarity: 188/544 - (34%)
• Gaps: 185/544 - (34%)

  Fly  2193 LCV---LSNRLCNTDIIDDSVTGSFQQIDLNRHLEIIYK---------------KVETLV----F 2235
            ||:   |.|.|...:     |.|:|...:::|.|:.:.:               :|:|.:    |
Human     8 LCIILWLENALGKLE-----VEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSF 67

  Fly  2236 SCVQRAFVLHTQSEFVEQLWNN-----------WSMYN-KLAKVTT---------EAQQHSVLDE 2279
            ..|....:.:|...|..|.|.:           .|:.| .::|:.|         ::..|::...
Human    68 GPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTP 132

  Fly  2280 LKLFSERLGSLGKIIEVLEAT-PQNCQVRALQ-----QLAEIKSQLLLLQTYIKTADSLNTGGSF 2338
            .|||  |:...|.|:..:..| ..:|.:|.:.     ....:|.                  ||:
Human   133 NKLF--RIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKF------------------GSY 177

  Fly  2339 EWVDSQIVTSLKCGQYILLEHVNLCSSAVLDRLNPVFEPNGSLLIAEKGISAQDSAEVVYKSTNF 2403
            .:..|:|:.:.|.|....:|               |.|.:.|||..:. |....|:|.:..:|..
Human   178 AYPKSEIIYTWKKGPLYSVE---------------VPEESSSLLQYDL-IGQTVSSETIKSNTGE 226

  Fly  2404 RAFLTVDPKNGELSRAMRNRCVELSLSRDTYSVDDLRAFVHEQGVREMEAIDCILRVHKGLSQLT 2468
            ...:||   ...|.|.|....:::      |:                   .||:.|.  |||::
Human   227 YVIMTV---YFHLQRKMGYFMIQI------YT-------------------PCIMTVI--LSQVS 261

  Fly  2469 EFNN---------YSISHLTQFAFLSAAYRRIGYELKRAIYVAAME-------VYVYSANTDLMG 2517
            .:.|         :.|:.:.....||.:.|   :.|.:..|..||:       .:|:||..:..
Human   262 FWINKESVPARTVFGITTVLTMTTLSISAR---HSLPKVSYATAMDWFIAVCFAFVFSALIEFA- 322

  Fly  2518 YGLSYYQNKLRE--------------VVLAQTEVFEEVAVIQEDFLSDVILNSGNLNSLTL-IKR 2567
             .::|:.|...:              .:...||..|...|:..|  |...|.. .:.||:| |..
Human   323 -AVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPD--SKYHLKK-RITSLSLPIVS 383

  Fly  2568 QAVALKVLLDGYTEGKIPQKL------LASLFHEMEKLKLDQRNPQKLIRHFLYMLYESSAIGDL 2626
            .:.|.|||    |...|.|..      |:..|....  |:||         :..:|:..:..|
Human   384 SSEANKVL----TRAPILQSTPVTPPPLSPAFGGTS--KIDQ---------YSRILFPVAFAG-- 431

  Fly  2627 ELRHLYLQPWLSKDTAFQELSQNL 2650
             ...:|...:|||||  .|:|.::
Human   432 -FNLVYWVVYLSKDT--MEVSSSV 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	108/544 (20%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359	9/42 (21%)
		Prothymosin	4843..4920	CDD:281265
		PHA03151	4856..5060	CDD:177546
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
GABRA6	NP_000802.2	Neur_chan_LBD	5..440	CDD:332142	101/528 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910