DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG13185 and Lipc

DIOPT Version :9

Sequence 1:NP_001097279.2 Gene:CG13185 / 36268 FlyBaseID:FBgn0033661 Length:5526 Species:Drosophila melanogaster
Sequence 2:XP_006243421.1 Gene:Lipc / 24538 RGDID:3009 Length:510 Species:Rattus norvegicus


Alignment Length:465 Identity:93/465 - (20%)
Similarity:152/465 - (32%) Gaps:145/465 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1541 ERLNCILEPERTVLLAEKGGISELDASPDFV--VQAKSGFQFLATMNPGGDFGKKELSPALRNRF 1603
            :||.|.|.|:....|.|.|    .::|...|  :...||.: .||:      ||...:.:..:..
  Rat    59 DRLGCQLRPQHPETLQECG----FNSSHPLVMIIHGWSGSE-SATV------GKDSDNDSQVDGL 112

  Fly  1604 TEVW------CLPSDNKE-------DLIEIAYNCMRRQKEHENQAI-NTHKVAEYLVDVVLHIRD 1654
            .|.|      .|.|...:       |.|.:||       :|...|: ||..|.:.:..::|.:.:
  Rat   113 LETWIWKIVGALKSRQSQPVNVGLVDWISLAY-------QHYAIAVRNTRVVGQEVAALLLWLEE 170

  Fly  1655 TNDKFKFSVRDILAWANYMVSNAKLSFAEQAIFGLETI--------------------------- 1692
            :   .||| |..:....|.:......||..::.|...|                           
  Rat   171 S---MKFS-RSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRITGLDPAGPMFEGTSPNERLSPDDA 231

  Fly  1693 -FLDAL---------------------EMLPHESQEQ-----VELLKS------NIVKQAIKQAS 1724
             |:||:                     :..|:....|     :||.|.      |.:.|.||.|.
  Rat   232 NFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTIKCAH 296

  Fly  1725 LILQEKFTLEEL--SEKRGTEVELNECRFGIRPFFIDVNQERLTSAKEDFLFDAPTTKQNLFRLL 1787
            ......| ::.|  |..:.|..:.:......:...::..:.|..|...|...|.|...:.||.:.
  Rat   297 ERSVHLF-IDSLQHSNLQNTGFQCSNMDSFSQGLCLNCKKGRCNSLGYDIRRDRPRKSKTLFLIT 360

  Fly  1788 SALS----------------LQKPV-------LLEGPPGVGKTSIV--ESIGSAIGYQIVRINLC 1827
            .|.|                ::||:       ||.....:.|..|.  |.|.|...|.:: |.| 
  Rat   361 RAQSPFKVYHYQFKIQFINQMEKPIEPTFTMTLLGTKEEIKKIPITLGEGITSNKTYSLL-ITL- 423

  Fly  1828 EHTDLADLFGTDLPAEDNLLESNTAATERQIRSFVWRDGPLLAALKAKNTWIL------------ 1880
             ..|:.:|.......|::.:.:|...|.:.|  .:|...|..|.|..|..|:.            
  Rat   424 -DKDIGELIMLKFKWENSAVWANVWNTVQTI--MLWDTEPHYAGLILKTIWVKAGETQQRMTFCP 485

  Fly  1881 --LDELNLAP 1888
              :|:|.|.|
  Rat   486 DNVDDLQLHP 495

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13185NP_001097279.2 MDN1 298..5521 CDD:227596 93/465 (20%)
P-loop_NTPase 315..505 CDD:304359
P-loop_NTPase <887..972 CDD:304359
P-loop_NTPase 1147..1283 CDD:304359
P-loop_NTPase 1454..1603 CDD:304359 16/63 (25%)
P-loop_NTPase 1795..1946 CDD:304359 27/117 (23%)
P-loop_NTPase <2335..>2378 CDD:304359
Prothymosin 4843..4920 CDD:281265
PHA03151 4856..5060 CDD:177546
MttA_Hcf106 <5046..5166 CDD:294511
vWA_midasin 5261..5526 CDD:238737
LipcXP_006243421.1 Lipase 18..366 CDD:278576 65/329 (20%)
Pancreat_lipase_like 47..362 CDD:238363 63/325 (19%)
PLAT_LPL 369..504 CDD:238856 28/132 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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