DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and F56A11.6

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	NP_499950.3	Gene:	F56A11.6 / 176884	WormBaseID:	WBGene00018926	Length:	419	Species:	Caenorhabditis elegans

Alignment Length:	282	Identity:	66/282 - (23%)
Similarity:	121/282 - (42%)	Gaps:	46/282 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  4775 DKRKEQAKDIDDMKDPEMDEEQTNAMHNELEEPPEPEEMDLGDMNNVDEGHDDQDEQPTDENPFD 4839
            :.||..|:   |.:.|....:..::||.    ||.|    .|..::.|...|::|.:.|:    |
Worm   181 EPRKHPAR---DERRPRSRRQSPSSMHG----PPPP----YGPPSDDDRRRDEEDRRRTE----D 230

  Fly  4840 IDAMKE-NMQPAEEPEADGDD-EHDANEEGDPQSDGSDSEEDEAGTEAKPAEEDHGEGEEATPED 4902
            :|..|: :::..||......| |.|       :|.|.:.......:..|..:.|       ....
Worm   231 VDRSKDRSLKRREERSRSRQDRERD-------RSRGGEKSRSPRKSHQKSVDRD-------KTRS 281

  Fly  4903 EKDEAETQKRGELEDEDDSKPEDSPEDSKEEKEEKREEKPEEHSQSKDKASKEENVQSMPETDQS 4967
            :||.:.::|     |.:|...|.|.:| :|:::.:|..|..|....||:..:|.. :|..|.:..
Worm   282 DKDRSRSRK-----DREDRDRERSRKD-REDRDRERSRKEREDRSRKDREDRERE-RSRKEREDR 339

  Fly  4968 SSADQVQQPQDPDIKQDQKLDEQETGEEKDGVGQAENDADDGGHQGVAETQETVSQEDRKNERQT 5032
            |..|:.:..||.: .:|:..|...:.:::|....:....||...    |.::..|::||:..|..
Worm   340 SRKDRERSRQDRE-DRDRDRDRDRSRKDRDDKSCSRRSRDDRSE----ERKDRKSRDDRERPRSR 399

  Fly  5033 QEKRKQGRTNEERSLGEAEQNK 5054
            |:|.|. |:.|:|.  .:..||
Worm   400 QDKSKT-RSVEDRP--RSRSNK 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	66/282 (23%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265	14/78 (18%)
		PHA03151	4856..5060	CDD:177546	46/200 (23%)
		MttA_Hcf106	<5046..5166	CDD:294511	2/9 (22%)
		vWA_midasin	5261..5526	CDD:238737
F56A11.6	NP_499950.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910