DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and Y25C1A.8

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	NP_494440.1	Gene:	Y25C1A.8 / 173655	WormBaseID:	WBGene00021295	Length:	345	Species:	Caenorhabditis elegans

Alignment Length:	400	Identity:	82/400 - (20%)
Similarity:	140/400 - (35%)	Gaps:	111/400 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  4599 DEEGQSKQESKNGEGFGLEDGTGENDASDKIESEDQL--DDAKRPEDR------KDEGDKQEPDC 4655
            |:..|.::..|:||...::....      |:..|..|  |:..:|:.|      |:.|.:|   .
Worm     7 DDREQKRRALKDGEWACVDSKCA------KVNEESLLVCDEYGKPKPRAKSKIGKELGKEQ---A 62

  Fly  4656 KEEKGIEMSDDF--------------------DAKMQDVEKPEEDDSGESEEE------EDLNKE 4694
            ::.||:..::|:                    ..|:.|:|:......|.::.:      .|.::|
Worm    63 EKSKGLFAAEDWVCSKCGNVNWARRRTCNVCNAPKLADLERRTGYGGGYNDRQNVEYVKRDYDEE 127

  Fly  4695 MGETEEGAEKLDDQIWGDDEEEKPEEEQEPDMNEEDQGKGSKDEKDAHNDLDTKNDAAKEDGKDE 4759
            ..|.  |.:|           :|..|:|..||.|   |:.|.||     ::..|:|..|...:.|
Worm   128 FDEF--GRKK-----------KKKGEDQFRDMEE---GEASDDE-----EIAVKDDLKKRTPRGE 171

  Fly  4760 HEKDGLDATNEPSGEDKRKEQAKDIDDMKDPEMDEEQTN---------AMHNELEEPPEPEEMDL 4815
            .|.|..|..:|...||.......:.|...|||:.|:..|         |..:|..:..|......
Worm   172 DEADEDDEADEDEDEDGEDLGKYNFDFDSDPELVEKVENLKSKIVAVAAAGSEACDDSECSCSCS 236

  Fly  4816 GDMNNVDEGHDDQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEHDANEEGDPQSDGSDSEEDE 4880
            |...:..|..|                         |.|.|....|..:.|.|.:|....|.
Worm   237 GGECSCPESED-------------------------EKEKDRRKMHKTSRERDRESHRKRSN--- 273

  Fly  4881 AGTEAKPAEEDHGEGEEATPEDE----KDEAETQKRGELEDEDDSKPEDSPEDSKEEKEEKREEK 4941
                 .|.:.|...|:.:.....    :|:...:||....:...|.|..:..|.:.: :|:|.||
Worm   274 -----SPRDRDRKRGKRSRSRSRERSYRDDRRDRKRSRSRERRRSPPRGTTSDRRRD-DERRREK 332

  Fly  4942 PEEHSQSKDK 4951
            ....|:|:|:
Worm   333 ERRRSRSRDR 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	82/399 (21%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265	14/80 (18%)
		PHA03151	4856..5060	CDD:177546	22/99 (22%)
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
Y25C1A.8	NP_494440.1	RanBP2-type Zn finger	21..42	CDD:275375	4/26 (15%)
		ZnF_RBZ	72..96	CDD:197784	1/23 (4%)
		RanBP2-type Zn finger	74..93	CDD:275375	0/18 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910