DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG13185 and Gabrg2

DIOPT Version :9

Sequence 1:NP_001097279.2 Gene:CG13185 / 36268 FlyBaseID:FBgn0033661 Length:5526 Species:Drosophila melanogaster
Sequence 2:NP_032099.1 Gene:Gabrg2 / 14406 MGIID:95623 Length:474 Species:Mus musculus


Alignment Length:438 Identity:74/438 - (16%)
Similarity:141/438 - (32%) Gaps:154/438 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly  2708 IPVSSVTTVQQMNALQYSQALCKKQVTEKYANHLLANFSSFLEVLHTSLLE---------DLE-T 2762
            :|...||.:  :|.|           .|.|.|.|..:......::||.:..         ::| |
Mouse    60 VPEGDVTVI--LNNL-----------LEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYT 111

  Fly  2763 ADLDLPQYAHLVTRFHWFNRILATAQQKLLYNNELHVPLMHKLVLHFQWLEKHLLVPLIELTAKS 2827
            .|:...|        .|::|       :|.:|:.:.|..::..::...|:.....     ..:|.
Mouse   112 IDIFFAQ--------TWYDR-------RLKFNSTIKVLRLNSNMVGKIWIPDTFF-----RNSKK 156

  Fly  2828 GCARMLTIQDRTLKI---KKYIEETRRPLNVTCKIYSKQF--------TQFQPY-YQDQQIQRHI 2880
            ..|..:|..:|.|:|   .:.:...|..::..|::....|        .:|..| |..::|    
Mouse   157 ADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEI---- 217

  Fly  2881 ELDDLEKLLSVVPSYGNLELSSWLKRWLLLQTDDANKWRSFLRKHTNGFQPKAFEISGSLRNETL 2945
                               :..|.:.  .::..|...||.:           .|...| |||.| 
Mouse   218 -------------------VYQWKRS--SVEVGDTRSWRLY-----------QFSFVG-LRNTT- 248

  Fly  2946 QSHLQKLQTTLKEAQENSAEIEMDLELDLNSIKTLLEAETEESES----YIHPDGIPTNT----- 3001
                :.::||..:....|...::...:...:|:|.:........|    :|:.|.:|..|     
Mouse   249 ----EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGIT 309

  Fly  3002 ----------------PKLLIAALRELFMERLLT---------GTL----------RDDFDEQVN 3031
                            ||:......:||:.....         |||          :|...::.|
Mouse   310 TVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKN 374

  Fly  3032 PLYADQLLTLNSNLWHCLKTLESANRTEITNAWIELKNEVNELQNYDE 3079
            ||.  ::.:..:      .|::...|    :|.|:: |....||..||
Mouse   375 PLL--RMFSFKA------PTIDIRPR----SATIQM-NNATHLQERDE 409

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13185NP_001097279.2 MDN1 298..5521 CDD:227596 74/438 (17%)
P-loop_NTPase 315..505 CDD:304359
P-loop_NTPase <887..972 CDD:304359
P-loop_NTPase 1147..1283 CDD:304359
P-loop_NTPase 1454..1603 CDD:304359
P-loop_NTPase 1795..1946 CDD:304359
P-loop_NTPase <2335..>2378 CDD:304359
Prothymosin 4843..4920 CDD:281265
PHA03151 4856..5060 CDD:177546
MttA_Hcf106 <5046..5166 CDD:294511
vWA_midasin 5261..5526 CDD:238737
Gabrg2NP_032099.1 LIC 68..471 CDD:273305 71/430 (17%)
Neur_chan_LBD 68..271 CDD:280998 44/277 (16%)
Neur_chan_memb 278..468 CDD:280999 26/145 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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