DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and TCEAL2

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	NP_525129.1	Gene:	TCEAL2 / 140597	HGNCID:	29818	Length:	227	Species:	Homo sapiens

Alignment Length:	204	Identity:	46/204 - (22%)
Similarity:	81/204 - (39%)	Gaps:	35/204 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  4800 MHNELEEPPEPEEMDLGDMNNVDEGHDDQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEHDAN 4864
            :.||.|..|.            ::|..|.:|||..|...::..:.|:    ::.|.:|:.|:...
Human     4 LFNENEGMPS------------NQGKIDNEEQPPHEGKPEVACILED----KKLENEGNTENTGK 52

  Fly  4865 EEGDPQSDGSDSEEDEAGTEAKPAEEDHGEGEEATPEDEKDEAETQKRGELEDEDDSKPEDSPED 4929
            ...:|.   .|.|:.|:..:||...:...:|:.......|.|.:.::.|..|.|.:...|..||.
Human    53 RVEEPL---KDKEKPESAGKAKGEGKSERKGKSEMQGGSKTEGKPERGGRAEGEGEPDSEREPES 114

  Fly  4930 SKEEKEEKRE--EKPEEHS---QSKDKASK---------EENVQSM--PETDQSSSADQVQQPQD 4978
            ..|.:.|.|.  ::|.|..   ::|.|.:|         :|.:..|  ...|.....|.:.:.:|
Human   115 EGEPESETRAAGKRPAEDDIPRKAKRKTNKGLAQYLKQYKEAIHDMNFSNEDMIREFDNMARVED 179

  Fly  4979 PDIKQDQKL 4987
            ...|..|||
Human   180 KRRKSKQKL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	46/204 (23%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265	16/76 (21%)
		PHA03151	4856..5060	CDD:177546	34/148 (23%)
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
TCEAL2	NP_525129.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..145		36/159 (23%)
		BEX	<123..202	CDD:282406	15/66 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..227
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910