DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and AgaP_AGAP009104

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	XP_553025.3	Gene:	AgaP_AGAP009104 / 1280056	VectorBaseID:	AGAP009104	Length:	319	Species:	Anopheles gambiae

Alignment Length:	291	Identity:	65/291 - (22%)
Similarity:	103/291 - (35%)	Gaps:	103/291 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly  1666 ILAWA-----NYM---VSNAKL--SFAEQAIF-----GLETIFLDALEMLPHESQEQVELLKSNI 1715
            ||.||     ||:   |.|.|.  |:....:.     ||.   :|.|.::.|....|   |...:
Mosquito    92 ILDWAQLADGNYLLEAVPNCKKLGSYLGSVVLRMINAGLN---VDKLHLVGHSLGGQ---LAGYV 150

  Fly  1716 VKQAIKQASLILQEKFTLEELSEKRGTEVELNECRF---GIRPFFIDVNQERLTSAKEDF----- 1772
            .:..|.|              ||||   |:||....   ...||:..:....|:|...||
Mosquito   151 GRTVIAQ--------------SEKR---VKLNRISALDPAFPPFYPGIFATALSSKDADFVDVIH 198

  Fly  1773 ----LFDAP-TTKQNLFRLLSALSLQKPVLLEGPPGVGKTSIVESIGSAIGYQIVRIN-LCEHTD 1831
                |:.|| :|....|...:..:||        ||..|.:          |:::..| ||.|.
Mosquito   199 TDAWLYGAPVSTGTADFWPNNGKTLQ--------PGCPKRN----------YKLLTDNDLCSHR- 244

  Fly  1832 LADLFGTDLPAEDNLLESNTAATERQIRSFVW---RDGPLLAALKAKNTWILLDELNLAPQSVLE 1893
            .:..|..:..||.|:      |:...::...|   :||                :::.|...|..
Mosquito   245 RSWWFWAESVAESNV------ASFHSVKCKSWDDFKDG----------------KVDRAAPIVHM 287

  Fly  1894 GLNAVLDHRGEVYI-----PELNKSFHLAGS 1919
            |::...|.:|:.|:     |..:|.  ::||
Mosquito   288 GIDCSSDAKGDYYLQTNGAPPYSKG--VSGS 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	65/291 (22%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359	26/134 (19%)
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265
		PHA03151	4856..5060	CDD:177546
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
AgaP_AGAP009104	XP_553025.3	Pancreat_lipase_like	27..304	CDD:238363	61/275 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910