Protein Alignment CG13185 and AgaP_AGAP009554

DIOPT Version :9

• Sequence 1: NP_001097279.2
• Gene: CG13185 / 36268
• FlyBaseID: FBgn0033661
• Length: 5526
• Species: Drosophila melanogaster
• Sequence 2: XP_310129.4
• Gene: AgaP_AGAP009554 / 1271352
• VectorBaseID: AGAP009554
• Length: 11410
• Species: Anopheles gambiae
• Alignment Length: 6359
• Identity: 1170/6359 - (18%)
• Similarity: 2139/6359 - (33%)
• Gaps: 2103/6359 - (33%)

  Fly    17 ELTANESEDNVFSQSLQKFIKKQKYVPQDV---ERLFRSLSEQ---LPLPAYTVPIAASFEEQLL 75
            ::..|||:....:|.::..:.|.|.:.|::   .|:..||.|:   |...|....|||..:
Mosquito  3413 KIEPNESQSWNSTQEIRSKLFKYKAILQEISGHRRVIDSLKEKADSLGADAQNEDIAAKVQ---- 3473

  Fly    76 LLLSMALRWDSASQRFHTYQLECVALSKLMNFSLDA----QRFAKSYFHDKPAPF---------- 126
                      |.::|:...:..|..|.:.:..||:.    ....||...::...|
Mosquito  3474 ----------SITERYELLKKSCSDLIRRLEQSLELCNKFNELQKSLLDEQDYLFGELKQLSDVS 3528

  Fly   127 -------EK-------QQSNGSLPSKKSKNGNHAADNLD------------DLELIKCCFQLL-- 163
                   ||       ||:||.:..|.........||.|            ||:.:|..|:..
Mosquito  3529 GNKRVVQEKVQKIDDLQQANGKMEEKFKNLAKLITDNNDLISYGAKTVMEQDLQKMKADFEKFIG 3593

  Fly   164 -----KSDTPYFRELWD--------WSSFIAT-------YTHNSSSPKTQLYCNYIVAMLTNMSA 208
                 :.:.....:|||        ..:|:|.       ||..||..:.|....|...:|..:.
Mosquito  3594 SIGDARVELQKRMQLWDDYQRDLDQIGAFLAEVEDTMRGYTLKSSLNEKQEQHEYYQTLLGRLK- 3657

  Fly   209 PQLNSLNEKISTKTRLEFDQEREQAWNTARNTLCSYTPDASDQLLNLHLHGINKSVTNIEGVLLP 273
                        :..||||:..:::....::        :.|..::.::..:.....::||.:..
Mosquito  3658 ------------QNALEFDKLLDKSSELLQS--------SGDTKISFNMQQLKARAQSVEGTVKE 3702

  Fly   274 TFNE------ENLEFYASTDGCYDRIVKVDST-----VVNLRSIALGVAAAKPICLSGPVGCGKT 327
            ...:      ::.::....|.|...:.::...     :.:.:||......|.|..:.|
Mosquito  3703 LAKKCEAAYGDHKQYRQRYDECDKELDEIRDVFDGCRMQHAQSIQSSNQQADPQAVLG------- 3760

  Fly   328 TLIEYLARKTGRICPKPNEIESREKAL--KKAEEEEQLLTPKKKAKTTGSKRKLEEVPLEELLDL 390
             .|:.|..|...:..:.|.:....:.|  ..|.:.:|::..:.:..|...:|..:||........
Mosquito  3761 -TIQTLLAKHNVVTVQCNAVSDSGEQLYATTASKGQQMIRSEIQELTAKCERLFDEVNDYARSYE 3824

  Fly   391 GETTKKSGFLRIQLGDQTDSKMLLGQYRCTDVPGEFVWLPGVLTQAVMHGYWLLLEDLD--AATQ 453
            |...|.|||:  :..||...                 ||..|..| :..|..:|...||  .|.|
Mosquito  3825 GRLAKLSGFM--EKADQLQE-----------------WLNSVEGQ-LGRGSLILKPTLDEKCAQQ 3869

  Fly   454 DTYTILSSLLERQCLSVPGFRDSV----KIEPGFQLFVTVRTNKSASNSSQKSLYSLLDKY---- 510
            ..|..|.:.::.....:...||.|    :..|..:..:...|:|......:...|.  |:|
Mosquito  3870 QAYAELLNDIKNHRPELNNVRDLVDNMQEQHPTIERRMAELTSKYEECLEKAQTYG--DQYDRIV 3932

  Fly   511 ----------LYTINILPLSRN--ELCKMVSINYPKLSTVANRIVDVFLTFSSGNHTSADNLRQQ 563
                      :.|.:.:..:.|  ||.....::...|.|..:|:.::..:.:: ..:..|.:|..
Mosquito  3933 HNHRQYCKAVMETQDFIDANHNTVELWGETDLDQVSLMTNLDRLTELKKSITA-EQSRVDQIRTL 3996

  Fly   564 ESGDKADNTEQYVALPFEQVPLTSSPNSGRLV---STRDLVKLCHRSNPQFSVTSSECAYFVFQ- 624
            ......|.:::..|....|:.::.....|.|.   ||.|.::........:....::|..::..
Mosquito  3997 GEATIPDTSDEGQANIRSQIDISQQEWEGLLAAIDSTMDGIRGKMGEWSDYEKIRTDCMNWMRDI 4061

  Fly   625 ----NAVDVFCSYLPQSKEKVTLITSIGAKLGIIRSRCEHFANEYKPDVEFGLEHIKIGRASLLA 685
                ::||:          |.|||                       |.:..|:::|..:..:.|
Mosquito  4062 DAKIHSVDL----------KATLI-----------------------DKKATLDYLKSLQGEVKA 4093

  Fly   686 KS-DLNN--------------SENEDISEQDLKRQKLSQQTRRAIGKVSNKRTTFSFTRLASCIL 735
            |. :::|              |.|..|||..:|.|:.:.:.:..:|:...
Mosquito  4094 KELEIDNFTEKAQQLYRGYLSSRNSQISELAVKYQQTASRIKELVGRWQQ--------------- 4143

  Fly   736 ERIAVCVTHSEPVLLVGETGVGKTSSVQYLAERTEHKLVVVNMNNQSDVSDLVGGFKPVELNYVL 800
                ..:.|.|.     ||.:|            ||:             |.:.|
Mosquito  4144 ----YVIQHQEL-----ETRIG------------EHR-------------DWLNG---------- 4164

  Fly   801 APLRNEFEYLLCETFNQEKNLQF-LRLFA-----THYNSGRHAVIIRTMINICLQV--------- 850
              :|.:..|....:...||.||. |:|..     ....|||    ::|::::..||
Mosquito  4165 --VREKLNYCADLSSTSEKELQSKLKLVQDMIVNKEDGSGR----LQTIVDLAQQVLACTTPSGH 4223

  Fly   851 -AKNPELKANKLLPRWQTLREKLQKLQMQLDKSINISFAFIPGSLVNCIS-NGDW---------- 903
             |.|..:.|  |...|.:|..::..::..||::||....|:  ..||.:. |.||
Mosquito  4224 EAVNKAVAA--LQEEWSSLALRMIDIRANLDEAINQWSGFL--DQVNDLKRNIDWMENELSGFVE 4284

  Fly   904 ---------------------VLLDEINL------------------ASAETLECLSTI--LEPE 927
                                 :.|::|.:                  |:|...:.||..  |..:
Mosquito  4285 FQASMADKRAQLERIKNTEEKIRLEKIEIEPLKQKTTEMAASGQQSQAAATAQQILSKFDYLAEK 4349

  Fly   928 GSVVLLERGDFTPVKRHPDFRIFACMNPNTDI------GKKDLPVGIRNRFTEFFVDELTTDADL 986
            .|.:|.:|.|     ::.|.|::  .....|:      .::.||...:...:    |:||.|:.:
Mosquito  4350 ISKILTDRED-----QYRDHRLY--KEAYDDLFNWISRAREKLPCVKQQSLS----DKLTMDSAI 4403

  Fly   987 S-------------LLVSDYLANTGIQRKSVHNIVQLYKSLRKLSELQLNDGLGNRPVYSLRTLC 1038
            :             ||| ::|.:||        .|.:..:..|..|             ::|:..
Mosquito  4404 APLDALMNKKAQGELLV-EHLVHTG--------EVVMASTSEKGKE-------------AIRSDI 4446

  Fly  1039 RSLRICARNLCGSIERNLYESFCLSFLTQLDPNSHHVVLLLIQNALLSNVKAILSKQLPQLGENY 1103
            ..|:....:|.|.|::.                                 |..|.|.|..|.|..
Mosquito  4447 NGLKANFESLFGDIDKQ---------------------------------KRDLEKTLNLLREYK 4478

  Fly  1104 LDFE--GYWIQP-----GNLEPQPCTHYILTESVKKNLKDLARIISIGKLPILLQGPTSAGKTSL 1161
            .::|  ..|:|.     .|.:...|::....|...:.:::|     ||||
Mosquito  4479 EEYERLSEWLQQVDILVKNHKLAMCSNLAEKEKQVREMREL-----IGKL--------------- 4523

  Fly  1162 IDYVARRSGNRCLRINNHEHTDLQEYIGTYAADLDGKLTFREGVLVQAMRHGFWIILDELNLAST 1226
                 .:......:.|......||.::.||..:....|..|..|              ::|||.
Mosquito  4524 -----EKGQGEMDKFNAFAAPLLQSHLDTYIGNQLRHLNSRYQV--------------QVNLAK- 4568

  Fly  1227 DILEALNRVLDDNRELYIAETQTLVKAHPNFMLFATQNPPGLYGGRKTLSRAFKNRFIELHFADI 1291
            |:|    :.::.|.:|:......|.||                           |.:|| :..:|
Mosquito  4569 DVL----KKVETNHDLHREYKDNLTKA---------------------------NGWIE-NAKEI 4601

  Fly  1292 PREELETI-------LEKRCFIPPTYARKMVQCMTQLQQHRKNTSKQVFTLRDLFRWGNRYTHAD 1349
            .|...|.:       ||||       ..|:|:.:.|.:|.:...:..|.|       |.:...:.
Mosquito  4602 VRYSTENVDSVSKDNLEKR-------LAKIVELIQQREQGQNLVNATVNT-------GEKVVKST 4652

  Fly  1350 KSLHDDNRYDWNQHLVEEGYLVLSSKVRSQEEH--ELIEK------TLFANFRKKLDLQTLFD-- 1404
            ||               :|..|::.:::..:.:  .|:::      .|..||.:..|..:.::
Mosquito  4653 KS---------------DGKEVINGEIKDIQTNWDRLVKRMSTAKVQLETNFLQWADYSSSYNHL 4702

  Fly  1405 ---IQTDRES------------------SSMVSRKILDAIRNFKLRDDIVWTRNMTRMAVVTAKA 1448
               || ||||                  ||.:|..:.:...|.:..:|||            ...
Mosquito  4703 QQWIQ-DRESKLQQVCEQKVVRFRLGGTSSSLSSGLNERRANLRQANDIV------------QDI 4754

  Fly  1449 LEFDEPVLLVGPTGCGKTTVCQLLASIADVQLRILNCHMHTEGADFLGGLRPCRGKESTQLFEWA 1513
            :.| ||::             |.:||.|. .||      .|..|..:........|::.::||
Mosquito  4755 VSF-EPMI-------------QSVASKAS-DLR------QTSPASEISNKYETLSKQAKEMFE-- 4796

  Fly  1514 DGPLIYAMQEGSYFMADEISLAEDSVLERLNCILEPERTVLLAEKGGISELDASPDFVVQAKSGF 1578
                                              :.:.||.|.:    :.:|||.:|....::..
Mosquito  4797 ----------------------------------KQKETVELHQ----AFIDASNEFAAWIRNAK 4823

  Fly  1579 QFLATMNPG-GD-------------------FGKKELSPALRNRFTEVWCLPSDNKE-DLIEIAY 1622
            :.|...:.. ||                   .|:|:|..||..  .||.|...:.:| :.||...
Mosquito  4824 ECLNKCSDSRGDKETLVSKMTQLKILDNDVPVGQKKLEKALEQ--AEVACRNVEGEEVEAIEKEV 4886

  Fly  1623 NCMRRQKEHENQAINTHKVAEYLVDVVLHIRDTND------------------------------ 1657
            ..:  |:|.:|..|...|::..|.:.::...:.:|
Mosquito  4887 AIL--QEEFDNYCIALKKISGALENGIVRWTEYDDQYGVALKWLDSIEQEVQTYNKMQANLQEKK 4949

  Fly  1658 ----KFKFSVRDILAWANYMVS----------------------------NAKLSFAEQAIFGLE 1690
                :|:..::.:..|...:.|                            |..||.|::.:..||
Mosquito  4950 RVLEEFQDKLQTLFDWQRELDSLNMRAQVLLEICADTRISNGVTQLTTKYNVLLSIAKEIMRRLE 5014

  Fly  1691 ----------TIF-------------LDALEMLPH---ESQEQVELLKSNIVKQAIKQASLILQE 1729
                      |::             |:..|.:||   |:|.::.::|.  ::|:::|.    |.
Mosquito  5015 LHYQEHQQHNTLYGECQDWLDRMREKLNECESVPHTVAETQSKLNIVKG--IRQSLEQG----QN 5073

  Fly  1730 KFT-LEELSEKRGTEVELNECRFGIRPFFIDVNQERLTSAKEDFLFDAPTTKQNLFRLLSALSLQ 1793
            |.. |.||.||.....|.:...      .|:.:.|.|.:..|..:.|...|:|.|...|:.|.
Mosquito  5074 KLRYLIELKEKIVLSTETSGAS------KIEEDTENLKTEYESLMVDITETRQRLTNHLAQLE-- 5130

  Fly  1794 KPVLLEGPPGVGKTS--IVESIGSAIGYQIVRINLCEHTDLADLFGTDLPAEDNLLESNTAATER 1856
                     .:||.|  :.|.:....|          ..|..:....:| |:..:|.....|.:|
Mosquito  5131 ---------DIGKLSRMVAEWVEEVQG----------KLDAGETMQNEL-ADKRVLLEKYRAIQR 5175

  Fly  1857 QIRSFVWRDGPLLAALKAK---NTWILLDELN-------------LAPQSVLEGLNAVLDHRGEV 1905
            :..::    ..|:..:|:|   |..|.::|.|             :|....||  |.|.:|  |.
Mosquito  5176 ETGNY----NELVEKIKSKMTDNANIDVEEFNKILTDYEAIVAKVVAEIERLE--NQVNNH--ER 5232

  Fly  1906 YIPELNKSFHLAGSTRIFACQNPLKQGGGRKGLPQSFLNRFTKVYLRKLSTEDLLHVVTEKYGKY 1970
            :...|.:.:....:||     ..::|.....|..:..:.|..|:...:||..|         ||.
Mosquito  5233 FKQALGELYEWMKTTR-----QTIQQSSDFHGDKEHIVGRIEKLKGIELSFAD---------GKV 5283

  Fly  1971 FDQLNAYFLELLDQKAE-GNLFEIYSGKESSCKSDSFDLGAR--------LVRFSEQLDRGVASM 2026
                      |||..|: ||.....||:|.........|.||        |.|.|.|
Mosquito  5284 ----------LLDNTADMGNSLAAISGQEGQATIKQELLQARADWEELEELARSSRQ-------- 5330

  Fly  2027 EFGYKGGPYEFNLRDIL-RWCDLLHNPQTGYILGASPSSFQAAFKDFLLTLYERMQLVYYQRMRC 2090
                       .|.|.| .|...|...:|   |||
Mosquito  5331 -----------TLEDCLASWDSFLDKSET---LGA------------------------------ 5351

  Fly  2091 DQDKSYIRNVFSTVFLCDAEYLNQVSNDVALYWTADKVYLNDVVLSRKQADVLDLVNRQEQSPLL 2155
                          ||  .||..:|:...|...|||            ||.||..:.|.:...|.
Mosquito  5352 --------------FL--EEYNVKVNGYGASEGTAD------------QAAVLSELKRIQDLILT 5388

  Fly  2156 LDSQRQQLKQIIETVHMEKPLLLCGSTDSGKTKLIDALCVLSNRLCNTDIIDDSVTGSFQQIDLN 2220
            ..|..::|..:.|.: |||                        ..|:|  :.|      :.:||.
Mosquito  5389 KKSTVEELNDVCEAL-MEK------------------------SACST--VRD------RTVDLQ 5420

  Fly  2221 RHLEIIYKKVETLVFSCVQRAFVLHTQSEFVEQLWNNW-SMYNKLAKVTTEAQQHSVL------D 2278
            :....:..||:..: :.:::..|.||:..:.::..|.| :..|...|..::.....||      .
Mosquito  5421 KSYSTLLGKVQGFI-TKLEKNLVSHTEFLYYKEEINKWLNDANATIKNCSDVAADDVLVIRQKVV 5484

  Fly  2279 ELKLFSERLGSLGKIIEVLEAT--------PQNCQVRALQQLAEIK------------------S 2317
            :|:..|..:....|:.|:|:.:        |::.|....|.:::|:                  :
Mosquito  5485 QLQSLSNSIPQGQKLFEMLQDSFTKSSYLYPEDKQTTMFQDISDIRDSLDTVIIGISSSLNNLNA 5549

  Fly  2318 QLLLLQTYIKTADSLN-----TGGSFEWVDSQ--IVTSLKCGQYILLEHVNLCSSAVLDRLNPVF 2375
            |...|::|.:....:|     |.|.||.:...  .:|.:|               .:|:||..:
Mosquito  5550 QASRLESYEELKRRINEWLATTEGVFEALPETHGEMTEVK---------------TLLERLKHI- 5598

  Fly  2376 EPNGSLLIAEKGISAQDSAEVVYKSTNFR-------AFLTVDPKNGELSR--AMRNRCVELSLSR 2431
                             ..|:.:|.::..       ....|:..:.|:.|  :::.||.:|| .:
Mosquito  5599 -----------------QTEISFKQSDLENLQQEAANLFDVNKCSAEMERVASLQARCSKLS-EK 5645

  Fly  2432 DTYSV-------DDLRAFVHEQGVREMEAIDCILRVHKGLSQLTEFNNYSISHLTQFAFLSAAYR 2489
            .:|.:       ||..|:.  |.::|:|  ..:|::.   .||...|:..|.:..|.....|.:.
Mosquito  5646 CSYQIRNLETELDDQMAYY--QNLQEIE--KWLLQIS---FQLMAHNSLYIYNREQTLEQIAQHE 5703

  Fly  2490 RIGYELKRAIYVAAMEVYVYSAN-TDLMGYGLSYYQNKLREVVLAQTEVFEEVAVIQEDFLSDVI 2553
            ::..|::|           |..| .|....|.|..:..:.:....::.:..::..|::.:.|  :
Mosquito  5704 KLLDEIQR-----------YQVNIDDFNAKGQSQIERYILKAPAIKSRIETQMKNIRDSYNS--L 5755

  Fly  2554 LNSG---------NLN-------SLTLIKRQ------AVALKVLLD--GYTEGK--------IPQ 2586
            ||:.         :||       :|..|.||      .||.:.||:  .|..|:        |..
Mosquito  5756 LNTSVQIKNRLHDSLNKFQEYEDTLDDINRQLDETEPLVAEERLLEVVDYAVGQSQLEKAQGIHN 5820

  Fly  2587 KLLASLFHEMEKLKL------------------------DQRNPQK--LIRHFLYMLYES----- 2620
            ||      ::||.:|                        .|..|:|  ::|..|..|.:.
Mosquito  5821 KL------QVEKSRLMFAVQACEAATASISRPSSPMDNVSQMIPEKELMVRARLEDLIDDVQQWI 5879

  Fly  2621 ----SAIGDLELRH---LYLQPWLSKD-----------------------TAFQELSQNL---YN 2652
                ::|.|.|.:|   :.|:.|:.|.                       .|..|||:.:   .:
Mosquito  5880 AELITSINDCERQHKQKVELENWIQKQKAIVADWGSKPCKFRPEAAEQELRAMSELSRTITVKRD 5944

  Fly  2653 CLQKRSNTD----------TGTLANLPWNRKLIPRLRDYSTAESNSELNPLNLSALLLARLVVDI 2707
            .||..:..|          .|:|      :|:|.|.:|...|......|..::...|      |.
Mosquito  5945 DLQGETEQDYRLREELEKLQGSL------KKVIDRKKDDQLAIEKYRKNYEDVQGWL------DA 5997

  Fly  2708 IPVSSVTTVQQMNALQYSQALCKKQVTEKYAN---------HLLANF----SSFLEVLHT----S 2755
            |       ..|::.::....|..||..||.:|         .::|||    ...:|::..    .
Mosquito  5998 I-------TNQIDNVEKGGGLSCKQKLEKISNIKRILENDCEMIANFKRNGDHIVELVSNLDAQQ 6055

  Fly  2756 LLEDLETADLDLPQYAHLVTRFHWFNRILATAQQKLLYNNELHVPLMHKLVLHFQW-LEKH--LL 2817
            :.|.|::.|   .:|..:..|   .||.|.....    .:::...|.:.:....|| ::|:  |.
Mosquito  6056 VTEQLKSID---RRYNDITKR---LNRRLDVIDS----TSKMFGKLRNDIGELSQWVVDKNGSLD 6110

  Fly  2818 VPLIELTAKSGCARMLTIQDRTLKIKKYIEETRRPLNVTCKIYSKQFTQFQPYYQDQQIQRHI-- 2880
            || .:|.:.:..|.  ..|.....:.|.||..:..::...|.:|...:..:| .:.||::..:
Mosquito  6111 VP-YQLGSDTKSAE--NQQQAFRSLLKEIEGKQSYVDTLGKRFSSIQSDLEP-NEKQQLETELQT 6171

  Fly  2881 --------------ELDDL-EKLLSVVPSYGNLELSSWLKRWLLLQTDDANKWRSFLRKHTNGFQ 2930
                          |||.: |.:|.....:.||:::   :.|:..:.:|.||           ..
Mosquito  6172 LTKNVGLLSERVRAELDKIVEDILCRKNMHNNLDVT---RAWIKTKQNDVNK-----------IS 6222

  Fly  2931 PKAFEISGSLRNE--TLQSHLQKLQTTLKEAQENSAEIEMDLELDLNSIKTLLEAETEESESYIH 2993
            .:...:|.::.:|  ..|.|.|    |::|.:||:.:   |:.   ..::.:::..:||.::.:.
Mosquito  6223 DQIPLLSSNVNSEIKLCQRHAQ----TIREFEENAFK---DVS---KQVREIMKDCSEEGKAKLA 6277

  Fly  2994 PD--GIPTNTPKLLIAALREL-FMERLLTGTLRDDFDEQVNPLYADQLLTLNSNLWHCLKTLESA 3055
            .:  .|.:...:|:.:..|:: ||||  ....|.:|:.:            ...:|:.|...||.
Mosquito  6278 QEFGDIESKLKELVESCARKIEFMER--EHGKRREFEGR------------KDRVWNWLNEAESI 6328

  Fly  3056 NRTEITNAWIE------------------LKNEVNELQNYDEFAVL-----LEK--IGGGYKGLR 3095
            ...:|.....|                  :|..|.|.:.| :.|:|     |:|  |....|.:|
Mosquito  6329 VSADIRTTSYEILKDQKQKFDKLCGECEVMKGVVKEAEEY-KSAILPTLNELDKTNINNQVKVMR 6392

  Fly  3096 SYQRQYRN--SVQCYQLENLSTRLDCVQGPSEEGSTDISSQFCYRGPALSGVILSLICQPNGQLR 3158
            .......|  .|:|.:||:.....       |:....|.|  |          .:.:.|..|:|:
Mosquito  6393 EKWNAISNVLKVKCKKLEDHLVEY-------EDALAKIQS--C----------AAFLVQVQGRLK 6438

  Fly  3159 SV--PLSE--------LLEWRSALQQTRHLIWENSQLLTSRYSGEVNNLLQAKENARQLLKEL-- 3211
            .:  |::.        ||.:...|...:....|.|.:|       :.||.|.:||:.:|.:.:
Mosquito  6439 EMNRPVTSRIENIQDFLLAYEQILGSLKDKRLEMSTIL-------LTNLPQLRENSAKLEEMIMG 6496

  Fly  3212 --EYVRKLSE----KEQKANQGFENCAKELEKMIEKLEKEEN--NNASMTKDFEVSLTNALVGAI 3268
              |.:|:|..    |||     |.....::.|:|.|:..:.|  :|.|.|.|..:...:.::.:|
Mosquito  6497 IEEQLRRLKAMLLLKEQ-----FIGAINDIVKLIAKINTDFNTVDNFSPTVDERLMRYSEILQSI 6556

  Fly  3269 ELC---LLTNTPLIDPVEKNRLKNEYIAED---------IDCLSTL------------------- 3302
            |.|   |:..|.          |...||.|         :|.:.:|
Mosquito  6557 EECEGLLVAATD----------KGHQIASDGTDLDRHNIMDQIHSLQQQLGSIKRSIELEQDKYQ 6611

  Fly  3303 -------TTAYDFMKIAMKYRHFGEEIYSE----LELRLRTALQRQQQLSQKLALRSEKCLYASL 3356
                   |.:.|...:...::...|.|.|.    |:|::     ..||.|..:||..:..:...:
Mosquito  6612 KQRAYHKTLSNDLFALVDWFKDNDEHIRSRPLFGLDLKM-----ADQQHSAHIALAGKANINLKM 6671

  Fly  3357 VQDITHFL-HSNGDC-ESLYKLFQLIHSEWENFQGLHVATSAQL----------KSSIEVLGKLD 3409
            ::|:...| ||:... :.|..:.....:..|.......|..|.|          :.|:|.:.|
Mosquito  6672 IEDLLGKLAHSDSKLPDDLQDMVDRARALQETIPAELTAREAYLTQNRQYRLEFRDSMERVKK-- 6734

  Fly  3410 LWLANAQRFVHHT---------LSRYSAYYQDFVEPIKCSVNQLRFG------------------ 3447
             ||..|:....||         ::......:||:.. :..:..|.:|
Mosquito  6735 -WLTAAEERFEHTKTFSFDQEKITVALKELEDFLHG-EAEIRTLLYGAIQEQADRLWNSLSELDQ 6797

  Fly  3448 ------LESLKVIFTRVQQAGSVSQAEQMQQTIGDIVQFPSQHP----LVIRNSRLYGLLAELPH 3502
                  |:.||...:.|....:|.|.|.:..:  |:|:...:|.    .|:..|:|...:..:|
Mosquito  6798 NQCLGELQQLKNRLSEVSHRAAVQQTELLSNS--DLVKSYKKHSSAVNSVLAKSKLDDTILTIP- 6859

  Fly  3503 SEYEYFRLLKAKLSELSNYIALGRVIDETTFAAYDDALSICNQTWQQEEHRRCQLKAEAESLYVT 3567
                   .|.|::..::..:.:.:|        ..:.|.|.|:..||..:|..|...:.    |.
Mosquito  6860 -------TLPARIDHINVLLNMLQV--------QQNELDILNELSQQIVNRADQYNRDR----VQ 6905

  Fly  3568 KTKGGVDSEELIEMQEIEHNFPTNLDEDFAEFVSQ-PTLEQVL-KLDKKASAKDKQSQIVVEEDY 3630
            |..|..:.:.......:|     .|.|:..:...| ..||.:| :|:.|       |.:::|:|.
Mosquito  6906 KETGDANRQWAANTSLLE-----TLRENLVQLQQQWDQLESILQELEVK-------SNLLLEKDR 6958

  Fly  3631 AFLARNFIDVMTRHTQVYYKEQPKSSKELELHLLAPYQARFQVFANLHGHYKT---------ALG 3686
            .      :|::     |:.::|.::.|.:..:||....|..|:....:...||         .|.
Mosquito  6959 G------LDLV-----VHSRDQTEAKKHIVENLLEDKTALGQLNTKANALAKTLIKALREQKLLP 7012

  Fly  3687 SSLEERACN------GLAFGLALQQKQLRDIELEEGVSSSPYDFYKDSNISEIQSCLD----VME 3741
            .||||:..:      .|:..||.:::|||||                  ::|:|..||    :.:
Mosquito  7013 QSLEEKLTHLNDINTRLSDNLAKKERQLRDI------------------LTELQHYLDQIGELAQ 7059

  Fly  3742 RIE--KRVLEQLEQYPEHAGLADIKLVISRIRRLPAHAPVVRFNTGFQLLRQKLALWNEVAHRNN 3804
            |||  ::.|.|:..:.|.  |...:..:..::.......|.|     :.||:::   ||......
Mosquito  7060 RIETVRKDLTQINPFDER--LYQTERALGAVKEAAESCSVQR-----EDLRRRI---NEQYLPAQ 7114

  Fly  3805 NLVSEEIEVAEFVQRWTRLELQHWRNCLGQTAAQVELQ-AYRY-------WFFIYNLLQQFIHQK 3861
            ..|..:::..        |||.. |:..|.:....:.| ||:.       :|.:|:.::.:|.|.
Mosquito  7115 KFVPSDLKEG--------LELLD-RSLSGISGTMEDYQGAYKKAKMIRTDYFTVYDRIKTWIEQA 7170

  Fly  3862 QLDHSYTDIKLAEQRFAQDHLLDAQDLGESQRLELAQVVRILRQFVEASCYGDF---HIRLQLLQ 3923
            :|..|             :|.:|..:|       .:::..:..:|      ||.   |.:| |..
Mosquito  7171 ELTIS-------------NHGIDPSEL-------KSKLTTLTGEF------GDMRTAHEQL-LFN 7208

  Fly  3924 GFELYLHNVERAGK----------INGLPPLIAALHNLQLYFSQFAGEIADSAKLRRSPI----- 3973
            |.|:..|..|.:.:          .:.|...||.:........|..|..|:..:|.:|.:
Mosquito  7209 GNEIVRHCTESSDRTATQANMDQLTHELDKTIALIEQKNQTVDQILGNWANFMRLYQSVVDWSIK 7273

  Fly  3974 -----EKKLKEFVKIQSYSKDLSYFSMRNSVASVHRNLNKFLKEYRLSIQEKISEVFQPKDSTAK 4033
                 |:||:.....::.....:|.....|:|.|.:||::...|:     :||:||.    |||
Mosquito  7274 IRALLERKLQLNTLHEAQQACQNYSGAVASLADVSQNLSEMNHEF-----DKINEVC----STA- 7328

  Fly  4034 DYTFGTDKGKGLRNYNKIKYLHTERQQFVASEKLLEKFAIQEEFLSDNT-LLQRLDKHFRTARHV 4097
             |.    :||          ||......:..|.:|.:   :..||.:.| ..|:.::...:.|..
Mosquito  7329 -YL----RGK----------LHEAETLKIDIETVLFE---RNLFLHETTEEWQQYERKIESVREW 7375

  Fly  4098 VKETLGQVPYGELITELDDLLASQLERCEHL------RSLNVDRSKERPQQK-------QEAKQI 4149
            :|:....:..|||.::   .|..||...|.:      :.:.|:.|.|:.|..       .:...|
Mosquito  7376 IKDAYLALNSGELKSK---PLRDQLRILEQMLADISAQKIKVNMSLEKLQVHFHSDIIYTDNPTI 7437

  Fly  4150 LQQKRKALTDLFKMLHRLGANYKTGLLELSLRNEFEDFQLPPYSIRSMLPRLHPTAQQLDEHLDL 4214
            :|..|..|.||.|:  .|.....|..|:.:|. :.|..|....:||..:  :|...|
Mosquito  7438 VQSGRTILADLDKL--NLDVFQTTQNLDQALA-QIEGCQAEMQTIRQRI--VHEEQQ-------- 7489

  Fly  4215 YYMKSVFKLKLLQNIMLTPLSELG-PPNIERIKGFAV-----DLFLLVQQQREHLSGSTKELHEL 4273
                       |:|| |:||.:.| ....|::|..|:     :.||      ..:||  |.:||
Mosquito  7490 -----------LRNI-LSPLHQTGDSEKHEQVKEIALMNAREEAFL------AEMSG--KMVHE- 7533

  Fly  4274 RNSLDSLRKLAEIIPQADINPSTLNFVKSADIAMEIKQHLRQIHYVLKQWKLLLSCAPSSFIEES 4338
                       |...:.|:...:|....|::   ||               .|::....||:.|
Mosquito  7534 -----------ETTIEHDVQQPSLPIESSSE---EI---------------ALMNAREESFLSE- 7568

  Fly  4339 ENRLLVRKISLAQSELHSL--C-IQILNSSQELLNELNNANLEYLSSEKCVTYQKSYAEIQENIK 4400
                    :|.::.::..:  | .||..||:|:  .|.||..|....|.......:...||...|
Mosquito  7569 --------VSASEPDVPQVPECSAQIEVSSEEI--ALMNAREESFLVEMSGPAPTTDVHIQTMPK 7623

  Fly  4401 KTLELLRTGQNDYLPLAQPIVELLDSVQLKNHTEIAPEAIDLANADTELANIAHSVLMSMQKIYK 4465
            :  |.:..|     |.|:.| ||:.          |.|...||....:.:::.|..
Mosquito  7624 E--EFMPAG-----PSAEEI-ELMS----------AREESFLAEMSGQHSDVKHDT--------- 7661

  Fly  4466 HHVKTDEVNQNGEAKEQDEESKEALQEQHLKKCLTGELTSDWQQLSLPRVLGKLSNVLLVLKHSH 4530
             ..|||:...:.....::.....|.:|..|            .::|.|..:.: |:|:|.
Mosquito  7662 -DAKTDDGAMSVVVSTEEIAIMNAREESFL------------AEMSAPITVTE-SDVVLE----- 7707

  Fly  4531 FEGKDKLLCVRRAIGLLPVLEQYQLLADYLLLQQLATHKVSAKMLSIVLTVFVEIGSKGFCVPPD 4595
                    ..:..|.:.|..|:..|:.|          :.|...:::|.....:|.|   .:|.:
Mosquito  7708 --------STQDPISMAPSAEEVALMND----------ECSVVDVTVVSETEPDISS---AIPAE 7751

  Fly  4596 --------LMQDEEGQSKQESKNGEGFGLEDGTGEND--ASDKIESEDQLDDAKRPEDRKDEGDK 4650
                    |.:.:....:|..:......||:..|:.:  ..:..:...:.|||...|..|.
Mosquito  7752 QSILDSSMLSETDRSMGEQLIETRTMIVLEESEGDEERVVREMCQESFRQDDASSVEVAKQ---- 7812

  Fly  4651 QEPDCKEEKGIEMSDDFDAKMQDVEKPEED---------DSGESEEEEDLNKEMGETEEGAEKLD 4706
                 .|..||..|:..|.::.::.:..|.         |:..|.::.|..:...:.||...:..
Mosquito  7813 -----TESLGIATSEVSDRELAEIYRTLEQSYLSMWQLRDAENSYQKLDAREAKAQAEEVVTETS 7872

  Fly  4707 DQIWGDDEEEKPEEEQEPDMNEE-----DQGKGSK-------------DEKDAHNDLDTKNDAAK 4753
            .......|....||...||..|:     ||.:..|             :.:.::..|.|. :..|
Mosquito  7873 IPCDTPAEALYVEETISPDKPEQSSKLIDQFEVMKTLSQSMINNWQLREAELSYEKLRTM-EMVK 7936

  Fly  4754 EDGKDEHEKDGLDATNEPSGEDKRKEQAKDIDDMKDPEMDEEQTNAMHNELEEPPE--------- 4809
            :...|..|...:::   |..||....:.|.:::...|: |.|:...:.:.::|.||
Mosquito  7937 DSETDRTENVQIES---PKTEDSVLIEDKLLEETVSPK-DNEKQELLKDSMDEAPELVVLETTAA 7997

  Fly  4810 --PEEMDLGDMNNVD--EGHDDQD---EQPTDENPFDIDAMKENMQPAEEPEADGDDEHDANEEG 4867
              ..|.|...:.:::  :.|.::.   .:..|::...:....:..||||..|::...|  ...:.
Mosquito  7998 TTSAETDSSPIESLEVMDVHVEESIVLPKANDQSASSVVVEAKYTQPAEGKESERSSE--LLVKN 8060

  Fly  4868 DP-QSDGSDSEEDEAGTEAKPAEEDHGEGEE-------ATPEDEKDEAETQKRG-----ELEDED 4919
            .| |.:.:..|.||..||...    :.:|.:       ..|....:...|.|..     ||..|.
Mosquito  8061 IPTQFETTFVEPDETTTEIVV----NRDGSKKITLRKVVQPAQSIESTITGKASIVTSVELAPEQ 8121

  Fly  4920 DSKPEDSPEDSK-----EEKEEKREEKPEEHSQSKD---KASKEENVQSMP--ETDQSSSADQVQ 4974
            ...|..:.|:|:     |..:...||:..|..|.:|   :||....|...|  ||.|:...:.::
Mosquito  8122 SDAPAITAEESRVVVDVEGVDVVLEEQSTEQKQQEDPVLEASSPPAVSDSPVLETAQTVVEEVLE 8186

  Fly  4975 QPQDPDIKQDQKLDEQETGEEKDGVGQAENDADDGGHQGVAETQETVSQE-----------DRKN 5028
            |.:...|..:|.:::|:..|      ........||...|...:...|.|           |...
Mosquito  8187 QLEQKLITAEQAVEQQQPDE------PLTEPLTAGGELSVPVERPVESLEDIWPPSQYVCVDNVP 8245

  Fly  5029 ERQTQEKRKQGRTNEERSLGEAEQNKLKQLKTIDQLKDSKESDDAEQEKP----EPMDQTEAE-- 5087
            ||.........||.|                |::.....:||::|:|..|    ...|..|.|
Mosquito  8246 ERSIPVSPVHVRTEE----------------TVEVPVQRQESEEAQQVWPTSPERGSDYIEIEPN 8294

  Fly  5088 --EYQHVKEPKNSDKTTLDNATEEQSKKIQHQEDEPPNEEEIEAENVDELMEAEEPA-------- 5142
              :.|.|||.:......:|.||.|.....:.||.|.|    |..|.|..:....|||
Mosquito  8295 VMKPQEVKEEETIVPIVMDEATLEHVAVDRDQEIEVP----IVMEGVISVSSVPEPADTTGEVLE 8355

  Fly  5143 --VDPEDDAELEQLGAE----------KTEQKSDKP-------SKTEKSKEQLETPEGMEIEGEV 5188
              |..::|..:....||          :.|.|..:|       |.|...:..||..|...:..|.
Mosquito  8356 QTVQVKEDLPIPTQVAEVPVETIVVKIEDENKQLEPIATVIAESPTVTDESTLEMIETTTLSSEP 8420

  Fly  5189 VLTMTVPRSSETTAHSNSEILLDKSSHAEDLSSAE---QIELRQQYQKQLTTFRVAQPEHEDYET 5250
            |:..|:.|:::|...|:|...:.:.....:|...|   |:::....:.|.::.||:
Mosquito  8421 VVETTITRTTDTIEDSDSCTTIQEQPAPPELVDDEMNLQVQVASIGETQSSSLRVS--------- 8476

  Fly  5251 WQGISNRMTQNARELCEQLRLILEPTKCTRLKGDYRTGRRINMKKIIPYIASQFRKDKIWLRRTK 5315
                                :.::||:..::.        :::.:|.|...:...::.   ::|.
Mosquito  8477 --------------------MTVDPTETKKIS--------VSLIEIKPSTGAALEEEG---KQTA 8510

  Fly  5316 -PAQRDYKITI---AIDDSKSMHHNNSKTLTLEAISLVSQALTLLESGRLSIV-----------S 5365
             |...:::...   |::..|...:.|.|....:......:.....: ||||:.           |
Mosquito  8511 VPESLEFEEISGLKAVERKKKGKNENEKASNTDQSGPEPKPAAPAD-GRLSVAQESEQRFDSYQS 8574

  Fly  5366 FGE--APQI-ILNHTEQFDGPRLVNALNFAQDKTKI-AGLLNFIRTANAEESGT 5415
            |.|  .||: .:|..|:...|.::......|:|..: ..::..|.|.:.::..|
Mosquito  8575 FTEEDQPQVSTVNVLEEAVEPEMIEVPITIQEKIVVPTEVIEAIYTEDVQQQTT 8628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	1110/6004 (18%)
		P-loop_NTPase	315..505	CDD:304359	38/197 (19%)
		P-loop_NTPase	<887..972	CDD:304359	22/142 (15%)
		P-loop_NTPase	1147..1283	CDD:304359	19/135 (14%)
		P-loop_NTPase	1454..1603	CDD:304359	27/168 (16%)
		P-loop_NTPase	1795..1946	CDD:304359	30/168 (18%)
		P-loop_NTPase	<2335..>2378	CDD:304359	8/44 (18%)
		Prothymosin	4843..4920	CDD:281265	20/89 (22%)
		PHA03151	4856..5060	CDD:177546	47/237 (20%)
		MttA_Hcf106	<5046..5166	CDD:294511	33/147 (22%)
		vWA_midasin	5261..5526	CDD:238737	27/174 (16%)
AgaP_AGAP009554	XP_310129.4	CH	6..104	CDD:278723
		SPEC	410..610	CDD:295325
		SPEC	621..820	CDD:295325
		PRK03918	1970..2556	CDD:235175
		SPEC	2861..3034	CDD:295325
		SPEC	3183..3387	CDD:238103
		SPEC	3324..3497	CDD:238103	20/97 (21%)
		SPEC	3608..3824	CDD:295325	37/244 (15%)
		SPEC	3829..4031	CDD:238103	41/224 (18%)
		SPEC	4053..4255	CDD:295325	52/301 (17%)
		SPEC	4363..4575	CDD:295325	53/316 (17%)
		SPEC	4473..4686	CDD:295325	53/313 (17%)
		SPEC	4804..5014	CDD:295325	33/217 (15%)
		SPEC	4913..5121	CDD:295325	34/219 (16%)
		SPEC	5231..5438	CDD:295325	66/344 (19%)
		Mplasa_alph_rch	5485..6273	CDD:275316	165/904 (18%)
		SPEC	5564..5770	CDD:238103	44/259 (17%)
		SPEC	5982..6192	CDD:295325	44/236 (19%)
		SPEC	6209..6411	CDD:238103	46/237 (19%)
		SMC_prok_B	6362..>7108	CDD:274008	171/869 (20%)
		Smc	6875..7603	CDD:224117	195/931 (21%)
		SPEC	9839..10046	CDD:295325
		SPEC	10368..10577	CDD:295325
		SPEC	10482..10689	CDD:295325
		SPEC	11077..11299	CDD:238103
		KASH	11354..11410	CDD:287506

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910