DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13185 and AgaP_AGAP007473

DIOPT Version :9

Sequence 1:	NP_001097279.2	Gene:	CG13185 / 36268	FlyBaseID:	FBgn0033661	Length:	5526	Species:	Drosophila melanogaster
Sequence 2:	XP_308400.4	Gene:	AgaP_AGAP007473 / 1269751	VectorBaseID:	AGAP007473	Length:	372	Species:	Anopheles gambiae

Alignment Length:	238	Identity:	59/238 - (24%)
Similarity:	102/238 - (42%)	Gaps:	53/238 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  4810 PEEMDLGDMNNVDEGHDDQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEHDANEE-------- 4866
            |:|||:.||.:.:|    .||:..||...|:            |.|:|:.:....:|
Mosquito    90 PDEMDMEDMGDEEE----DDEELEDEEEEDV------------PAANGNSKARTAKEVAKAKVAK 138

  Fly  4867 ---GDPQSDGSDSEE--------DEAGTEAKPAEEDHGEGEEATPEDEKDEAETQKRGELEDEDD 4920
               ....|:|||:|:        |::.. ...||:|..:.:|...:|..|:.:.:  .|.||:||
Mosquito   139 KIAAGEVSEGSDAEDTTFSESMHDDSAI-VNGAEDDDDDDDEEDDDDSDDDEDVE--DEEEDDDD 200

  Fly  4921 SKPEDSPEDSKEEKEEKREEKPEEHSQSK----DKASKEENVQSMPETDQSSSADQ----VQQPQ 4977
            ...||..||..||.||..:.|..:..|:|    .||:...|.::..|..:.....|    ::..|
Mosquito   201 DDEEDDDEDDDEEDEEDEDVKQPKAKQAKLANDGKAAVNGNAKAAKEAPKKQEQQQKKGGMRTLQ 265

  Fly  4978 DPDIKQDQKL---DEQETGEE----KDGVGQAENDADDGGHQG 5013
            |..:.:|.|:   .|.:.|::    .:|..::.|...|..::|
Mosquito   266 DGLMVEDLKVGNGPEAKPGKKIAVYYEGRLKSNNKVFDSTNKG 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13185	NP_001097279.2	MDN1	298..5521	CDD:227596	59/238 (25%)
		P-loop_NTPase	315..505	CDD:304359
		P-loop_NTPase	<887..972	CDD:304359
		P-loop_NTPase	1147..1283	CDD:304359
		P-loop_NTPase	1454..1603	CDD:304359
		P-loop_NTPase	1795..1946	CDD:304359
		P-loop_NTPase	<2335..>2378	CDD:304359
		Prothymosin	4843..4920	CDD:281265	19/95 (20%)
		PHA03151	4856..5060	CDD:177546	45/192 (23%)
		MttA_Hcf106	<5046..5166	CDD:294511
		vWA_midasin	5261..5526	CDD:238737
AgaP_AGAP007473	XP_308400.4	FKBP_C	280..369	CDD:278674	6/29 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910