|
Fly 16 LELTANESEDNVFSQSLQKFIKKQKYVPQDVERLFRSLSEQLPLPAYTVPIAASFEEQLLLLL-- 78
|.|.|.::|.: |..|.:|:.|..:.|||.:.:..||::.|....||:.:.......||.||
Mouse 13 LRLIAAKNEKS--SGELNRFLAKSVWTPQDRQCILDSLAQLLLDKDYTLLLGRQLRPILLDLLER 75
Fly 79 -SMALRWDSASQRFH-TYQLECVALSKLMNFSLDAQRFAKSYFHDKPAPFEK--QQSNGSLPSKK 139
:.|:: :..|..| .::...|::|||:....|...||..||.|....|:: .:|:.:.|.:.
Mouse 76 NAKAIK--TGGQVNHDLHERLSVSMSKLIGSHPDVLPFALRYFKDTYPVFQRLFLESSDANPVRY 138
Fly 140 SKNGNHAADNLDDLELIKCCFQLLKSDTPYFRELWDWS----------SFIATYTHNSSSPKTQL 194
.:......| |::.....|:.....|||||||| :.:..:|.|
Mouse 139 GRRRMKLRD------LMEAANIFLQHRQTVFRELWDWSVCVPLLRSHDALVRWHTAN-------- 189
Fly 195 YCNYIVAMLTNMSAP-------QLNSLNEKISTKTRLEFD---QEREQAWNTARNTLCSYTPDAS 249
| :|::|.|:.. ::.|.:|.:..:.||..: |:.|:|...|...:..:.....
Mouse 190 -C---LALVTCMNEEHKLSFLRKIFSSDELVHFRLRLLEEAQLQDLEKALVLANPEVSLWHKGEE 250
Fly 250 DQLLNLHL--HGINKSVTNIEGVLLPTFNEENLEFYASTDGCYDR------IVKVDSTVVNLRSI 306
.|.:..|| ..::.||..:.||:||..:....|..:......:: .|.|:|...||:.:
Mouse 251 PQYIQGHLVSADLSSSVAAVCGVVLPKLSSSPGEQASDRSSSLEQELALKSFVLVESVCKNLQLL 315
Fly 307 ALGVAAAKPICLSGPVGCGKTTLIEYLARKTGRICPKPNEIESREKALKKAEEEEQLLTPKKKAK 371
|:.||:...:.|.||:|.|||:|:|:||..|||
Mouse 316 AVSVASQNAVLLEGPIGSGKTSLVEHLAAVTGR-------------------------------- 348
Fly 372 TTGSKRKLEEVPLEELLDLGETTKKSGFLRIQLGDQTDSKMLLGQYRCTDVPGEFVWLPGVLTQA 436
||....|::|||||||||||||.||||||||||||.||.||||
Mouse 349 ----------------------TKPPQLLKVQLGDQTDSKMLLGMYRCTDVPGEFVWQPGTLTQA 391
Fly 437 VMHGYWLLLEDLDAATQDTYTILSSLLERQCLSVPGFRDSVKIEPGFQLFVTVRTNKSASNSSQK 501
...|||:||||:|.|..|..::|..|||...|.:||..|.:|:.|.||||.| |...|...|..:
Mouse 392 ATKGYWILLEDIDYAPLDVVSVLIPLLEHGELLIPGHGDCLKVAPTFQLFAT-RRLLSCGGSWYR 455
Fly 502 SLYS---LLDKYLYTINILPLSRNELCKMVSINYPKLSTVANRIVDVFLTFSSGNH----TSADN 559
.:.| :||||...|::..|::.:|.:::...||.|....:.::|:::..:...| .:.|.
Mouse 456 PMNSHATMLDKYWTKIHLHNLNKKDLNEVLQSKYPSLLAATDHLLDIYIELTGEKHCCPSVAYDK 520
Fly 560 LRQQESGDKADNTEQYVALPFEQVPLTSSPNSGRLVSTRDLVKLCHRSNPQFSVTSSECAYFVFQ 624
..|:.| :|:...:.|.| .||.:|.|||:..|:|....|..|||.....:||
Mouse 521 APQEVS--EAERENRRVVL------------EGRELSLRDLLNWCNRVAHGFDPTSSTALLHIFQ 571
Fly 625 NAVDVFCSYLPQSKEKVTLITSIGAKLGIIRSRCEHFANEYKPDVEFGLEHIKIGRASLLAKSDL 689
.|:|.|.:.|.:..:|:.:...||::|.|.:.:.|.:...|||::......:::||..||.|.
Mouse 572 EAMDCFTAMLSEQTKKLRMAEVIGSRLNISKKKAEFYCKLYKPEIVINELDVQVGRVRLLRKQ-- 634
Fly 690 NNSENEDISEQDLKRQKLSQQTRRAIGKVSNKRTTFSFTRLASCILERIAVCVTHSEPVLLVGET 754
|| :.::..::.||:.||.:|.:||::||||:..|||||||||
Mouse 635 --------SE---------------VVRIQKEKCTFAATRPSSVLLEQLAVCVSQGEPVLLVGET 676
Fly 755 GVGKTSSVQYLAERTEHKLVVVNMNNQSDVSDLVGGFKPVELNYVLAPLRNEFEYLLCETFNQEK 819
|.||||:|||||..|...|.|||||.|||.:||:||||||:...:..|||..||.|..:||::::
Mouse 677 GTGKTSAVQYLAYATGQHLRVVNMNQQSDTADLLGGFKPVDHKLIWLPLRETFEELFVQTFSKKQ 741
Fly 820 NLQFLRLFATHYNSGRHAVIIRTMINICLQVAKNPELKANK------LLPRWQTLREKLQKLQMQ 878
|..||....|.|...|...:::.| |.|.|:...|..: |..:|:....:|...|.|
Mouse 742 NFTFLGHIQTCYRQKRWHDLLKLM----LHVQKSASTKGGEQSQPGLLKEKWEAFGLRLNHAQQQ 802
Fly 879 LDKSIN-ISFAFIPGSLVNCISNGDWVLLDEINLASAETLECLSTILE-PEGSVVLLERGDFTPV 941
:..:.| :.|||:.|:|...|..|:|:||||||||:.|||||||.:|| ..||:|||:|||..|:
Mouse 803 MKMTENALLFAFVEGTLAQAIKKGEWILLDEINLAAPETLECLSGLLEGSSGSLVLLDRGDTEPL 867
Fly 942 KRHPDFRIFACMNPNTDIGKKDLPVGIRNRFTEFFVDELTTDADLSLLVSDYLANTGIQRKSVHN 1006
.||||||:||||||.||:||::||.||||||||.:|:||.:..||.:|:.|||....:.:.:|..
Mouse 868 VRHPDFRLFACMNPATDVGKRNLPPGIRNRFTELYVEELESKEDLQILIVDYLKGLNVSKNTVQG 932
Fly 1007 IVQLYKSLRKLSELQLNDGLGNRPVYSLRTLCRSLRICARNLCGSIERNLYESFCLSFLTQLDPN 1071
||..|.:|||.|..:|.||.|:||.||||||||:||..|.|.||||:|:|||.|||.||||||..
Mouse 933 IVNFYTALRKESGTKLVDGTGHRPHYSLRTLCRALRFAASNPCGSIQRSLYEGFCLGFLTQLDRA 997
Fly 1072 SHHVVLLLI-QNALLSNVKAILSKQLPQ-LGENYLDFEGYWIQPGNLEPQPCTHYILTESVKKNL 1134
||.||..|| |:.:..|||::|.:.:|: .|...:..|||||..|:.||:....|:||.|||.||
Mouse 998 SHPVVQKLICQHIISGNVKSLLKQPIPEPKGGRLIQVEGYWISVGDKEPKIDETYVLTPSVKLNL 1062
Fly 1135 KDLARIISIGKLPILLQGPTSAGKTSLIDYVARRSGNRCLRINNHEHTDLQEYIGTYAADLDGKL 1199
:|:||::|.|..|:|:||.||.||||||.::|..|||.|:|||||||||:|||||.|.:|..|||
Mouse 1063 RDIARVVSAGTYPVLIQGETSVGKTSLIRWLAAASGNHCVRINNHEHTDIQEYIGCYTSDTSGKL 1127
Fly 1200 TFREGVLVQAMRHGFWIILDELNLASTDILEALNRVLDDNRELYIAETQTLVKAHPNFMLFATQN 1264
.|.||||:.|||.|:||:|||||||.||:||||||:|||||||.|.|||.:|:|||.||||||||
Mouse 1128 VFNEGVLIDAMRKGYWIVLDELNLAPTDVLEALNRLLDDNRELLITETQEVVRAHPRFMLFATQN 1192
Fly 1265 PPGLYGGRKTLSRAFKNRFIELHFADIPREELETILEKRCFIPPTYARKMVQCMTQLQQHRKNTS 1329
|||||||||.|||||:|||:||||.::|..||||||.|||.:||:|..|:|:.|..||.:|:.:|
Mouse 1193 PPGLYGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRRSS 1257
Fly 1330 ----KQVF-TLRDLFRWGNRYTHADKSLHDDNRYDWNQHLVEEGYLVLSSKVRSQEEHELIEKTL 1389
||.| .|||||||..||..|:::..| |||.|||..:|:::|:.:||.|||.::|::.|
Mouse 1258 VFAGKQGFIALRDLFRWAERYRLAEQTQED---YDWLQHLANDGFMLLAGRVRKQEEADVIQEVL 1319
Fly 1390 FANFRKKLDLQTLFDIQTDRE--SSSMVSRKILDAIRNFKLRDDIVWTRNMTRMAVVTAKALEFD 1452
..:|:|||..|:||..:...: ..|.....:|:: .| ..:|||.:|.|:||:..:||||.
Mouse 1320 EKHFKKKLCPQSLFSKENVLKLLGKSSTQTTVLES--KF---SHVVWTESMRRLAVLVGRALEFG 1379
Fly 1453 EPVLLVGPTGCGKTTVCQLLASIADVQLRILNCHMHTEGADFLGGLRPCRGKES------TQLFE 1511
|||||||.||||||||||:.:::|:.:|..:|||::.|.:||||||||.|.|.: |:|||
Mouse 1380 EPVLLVGDTGCGKTTVCQMFSALANQKLYSVNCHLNMETSDFLGGLRPVRQKPNDKDELDTRLFE 1444
Fly 1512 WADGPLIYAMQEGSYFMADEISLAEDSVLERLNCILEPERTVLLAEKGGISELDASPDFVVQAKS 1576
|.||||:.||:|.|:|:.||||||:||||||||.:||.|:.::|||||.....|...:.:...|.
Mouse 1445 WHDGPLVLAMKEDSFFLLDEISLADDSVLERLNSVLEVEKCLVLAEKGSPESKDNEVELLTAGKH 1509
Fly 1577 GFQFLATMNPGGDFGKKELSPALRNRFTEVWCLPSDNKEDLIEIAYNCMRRQKEHENQAINTHKV 1641
|:.|||||||||||||||||||||||||:||..|..:||||:|..:.:|..............|
Mouse 1510 -FRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTKREDLIQIINHNLRPGLSLAGVGHKGAGV 1573
Fly 1642 AEYLVDVV--LHIRDTNDKFKFSVRDILAWANYMVSNAK-------------LSFAEQAIFGLET 1691
||.::..: |..::...|...|:||||:|.|:|.|.|: .||...|..
Mouse 1574 AEVMLAFITWLTRQEFGRKCVVSIRDILSWVNFMNSMAEDAAVKRPEAISTVTSFVHAACL---- 1634
Fly 1692 IFLDAL-----------EMLPHESQEQVELLKSNIVKQAIKQASLILQEKFTLEELSEKRGTEVE 1745
:::|.: .:|..| |.||. ::|:..|...|..::|..|:.....|..|..
Mouse 1635 VYIDGIGSGVTSSGFGTALLARE-----ECLKF-LIKKLSKVVRLTQRQKDELKIYDRLRHKEFT 1693
Fly 1746 LNECRFGIRPFFIDVNQERLTSAKEDFLFDAPTTKQNLFRLLSALSLQKPVLLEGPPGVGKTSIV 1810
..:..:|:.||||............|:...|.||..|..|||.|..|.||:||||.|||||||:|
Mouse 1694 SIDDFWGVHPFFIPRGPVLDGHNTGDYALTAGTTAMNAQRLLRAAKLNKPILLEGSPGVGKTSLV 1758
Fly 1811 ESIGSAIGYQIVRINLCEHTDLADLFGTDLPAEDNLLESNTAATERQIRSFVWRDGPLLAALKAK 1875
.::..|.|..:|||||.|.||:.||||.|||.|.. :...|.|.||||||||||.
Mouse 1759 AALAKASGNTLVRINLSEQTDITDLFGADLPVEGG-----------RGGEFAWCDGPLLAALKAG 1812
Fly 1876 NTWILLDELNLAPQSVLEGLNAVLDHRGEVYIPELNKSFHLA-GSTRIFACQNPLKQGGGRKGLP 1939
: |::|||||||.||:||||||..|||||:|:|||..||.:. ..||||.||||.:|||||||||
Mouse 1813 H-WVVLDELNLASQSILEGLNACFDHRGEIYVPELGMSFQVQHEKTRIFGCQNPFRQGGGRKGLP 1876
Fly 1940 QSFLNRFTKVYLRKLSTEDLLHVVTEKYGKYFDQLNAYFLELLDQKAEGNLFEIYSGKESSCKSD 2004
:|||||||:|::..|:..|:..:.:..: ..:|:
Mouse 1877 KSFLNRFTQVFVDPLTVVDMEFIASTLF------------PTIDK-------------------- 1909
Fly 2005 SFDLGARLVRFSEQLDRGV-ASMEFGYKGGPYEFNLRDILRWCDLLHNPQTGYILGASPSSFQAA 2068
|:..::|.|:..:|..| ...::|.||||:||||||:.|||.|: ::..||..:...
Mouse 1910 --DIVKKMVAFNNHIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLI-------LVDQSPGCYDPG 1965
Fly 2069 FKDFLLTLYERMQLVYYQRMRCDQDKSYIRNVFSTVFLCDA-EYLNQVSNDVALYWTADKVYLND 2132
:.:.|||.:|||..:||..:..||..||..:: .|:......:..| .:.:..
Mouse 1966 ---------QHVFLVYGERMRTREDKEKVVAVFKDVFASNSMPYIGTRQFHITPY----DIQIGY 2017
Fly 2133 VVLSRKQADVLDLVNRQEQSPL-LLDSQRQQLKQIIETVHMEKPLLLCGSTDSGKTKLIDALCVL 2196
.||||. ..|....:.|| ||....|.|:.|::.|.|...::|.|....|||.|:..|..|
Mouse 2018 SVLSRS-----SYVPHPSRRPLSLLHQSFQSLEPIMKCVQMNWMVILVGPASVGKTSLVQLLAHL 2077
Fly 2197 SNR-----LCNTDIIDDSVTGSFQQIDLNRHLEIIYKKVETLVFSCVQRAFVLHT-QSEFVEQLW 2255
:.. ..|:.:....:.|.|:|:|:.|...::.:|||..|...::.:.:::: .:|.|.|.|
Mouse 2078 TGHTLKIMAMNSAMDTTELLGGFEQVDIIRPWRLLLEKVERTVRVLLRDSLLINSVDTEVVLQAW 2142
Fly 2256 NNWSMYNKLAKVTTEAQQHSVLDELKLFSERLGSLGK--IIEVLEATPQNCQVRALQQLAEIKSQ 2318
:::.:..| .:.||..|| .||::. ::::.
Mouse 2143 SHFLLTYK--------------------PKCLGEDGKGVTIEIVN---------------KLEAV 2172
Fly 2319 LLLLQ-------TYIKTAD-------------------SLNTGGSFEWVDSQIVTSLKCGQYILL 2357
|||:| :|.| || |..:.||||||||.:|.:||.|.::|:
Mouse 2173 LLLMQRLNNKINSYSK-ADFAKLVEDFRSFGVKLLQSASGRSHGSFEWVDSMLVQALKSGDWLLM 2236
Fly 2358 EHVNLCSSAVLDRLNPVFEPNGSLLIAEKGISAQDSAEVVYKSTNFRAFLTVDPKNGELSRAMRN 2422
::||.|:.:||||||.:.||.|.|.|.|:|: ...|...|..:.|||.||::||.:||:||||||
Mouse 2237 DNVNFCNPSVLDRLNALLEPGGVLTINERGM-VDGSTCTVTPNPNFRLFLSMDPIHGEISRAMRN 2300
Fly 2423 RCVELSLS-RDTYSVD---DLRAFVHEQGVREMEAIDCILRVHKGLSQLTEFN-NYSISHLTQFA 2482
|.:|:.:| .:..|:. ||:..:|..|:......:.:|.:|..:..|...: ..|:|.|:..|
Mouse 2301 RGLEIYISGEEDGSIQDNLDLKVLLHSLGLVGDSVCNILLALHTEIQSLVRGSPASSVSTLSHTA 2365
Fly 2483 FLSAAYRRIGYELKRAIYVAAMEVYVYS----ANTDLMGYGLSYYQNKLREVVLAQTEVFEEVAV 2543
.|...|.:.|..|.:|.:.|..||||.| ||..|:
Mouse 2366 ILIVQYLQRGLSLHKAFFEACWEVYVCSQHSAANQKLV--------------------------- 2403
Fly 2544 IQEDFLSDVILNSGNLNSLTLIKRQAVALKVLLDGYTEGKIPQKLLASLFHEMEKLKLDQRNPQK 2608
:|.|.. ::.:|..|:.....:|..|.....:|..|.|: |..:|.:.:...|.
Mouse 2404 --QDLLES--------HTASLQARETWGHSILATGLWPDSVPSALFAT---EDSRLSVVRSEGQI 2455
Fly 2609 LIRHFLYMLYESSAIGDLELRHLYLQPWL-SKDTAFQELSQNLYNC------------------- 2653
| .|.|...| |....|. |:....|:|...:..|
Mouse 2456 L----AYCLNRMS---------LKTSSWTRSQPLTLQDLENIMQTCSPDDLTFNAVEVDTCWVDE 2507
Fly 2654 -----------LQKRSNTDTGTLANLPW---NRKLIPR---------------LRD-YSTAESNS 2688
:::.:|.| .:..:.| ..|.||: ||. |||:.|..
Mouse 2508 PEVLATAVKLLIERATNQD--WMLRVKWLCHLAKNIPQGLESVRVHLEASATALRKFYSTSLSAG 2570
Fly 2689 ELNPL-------------------NLSALLLARLVVDIIPVSSVTTVQQMNALQYSQA------- 2727
..|.| |:.||.:.|..:|..|.|. ..:|:.||..|.|
Mouse 2571 VSNVLKILQTNITDDFVIPLDPRWNMQALDIIRNSLDFDPQSD--QAKQLFALLESVANKTFIYL 2633
Fly 2728 --------------LCKKQV--------------TEKY---ANHLLANFSSFLEVLHTSLLEDLE 2761
:..|:: .|.| .:.::||.::|.|::...:|..::
Mouse 2634 DREKRIFTEANLVSVGSKKLRSSVLRMSFEFHKDPENYHSPPHEIVANLAAFFELIDGLILLWVQ 2698
Fly 2762 TADLDLPQYAH---LVTRFHWFNRILATAQQKLLYNNELHVPLMHKLVLHFQWLEKHLLVPLIEL 2823
:....:|. || ::....|.:|....|....:..:.|.: |.||:.|:.|||:..:.:|
Mouse 2699 SPQGVVPD-AHINKILGSVQWRDRFWTVADTVTVDASGLAL-----LALHWHWVSKHLIYQIPQL 2757
Fly 2824 TAKSGCARMLTIQ--------------DRTLKIKKYIEETRRPLNVTCKIYSKQFTQFQPYYQDQ 2874
...........:| |....:||......||.....|:....|.|.|...:..
Mouse 2758 LVNQENKYYKELQTVSEHIHSCLGSPADSFAGVKKLQAFLGRPFPFKDKLVVDCFLQLQALNRAL 2822
Fly 2875 QIQRHIEL-------DDLEKLLSVVPSYGNLELSSWLKRW-LLLQT---DDANKWRSFLRKHTNG 2928
.|...:.: :|:.: |.||.|..||: .|.|:.| |:|:. :|.| |.:..|.
Mouse 2823 AIGEQLPVFGECGWQEDINR-LQVVASEWNLK-KSLLQAWGLILRANILEDVN-----LDELKNL 2880
Fly 2929 FQPKAFEISGSLRNETLQSHLQKLQTTLKEAQENSAEIEMDLELDLNSIKTLLEAETEESESYIH 2993
...:..| |::..|. :..|::|.:.|:..:.|| .|.:|
Mouse 2881 VSTQCSE----LKSRGLS------RGFLEKAHDASSPSQPDL------------------SSLVH 2917
Fly 2994 PDGIPTNTPKLLIAA--LRELFMER----------LLTGTLRDDFDEQVN----------PLYAD 3036
.|...:|..|| |..|:..| |...:..|..||::: |:...
Mouse 2918 ----LTRRVQLWPAAEYLAMLWQYRVTADFIAQACLRRSSKHDQMDEEISHHIAFCLKHTPIAPQ 2978
Fly 3037 QLLTLNSNLWHCLKTLESANRTEITNAWIELKNEVNELQNYDEFAVLLEKIGGGYKGLRSYQRQY 3101
:|. |||..|. :|..:..|::..|.|| .....|. |:....
Mouse 2979 KLW----NLWSLLH-IEMLSAQEVSCLWSEL---------------FTSTFGS------SWSSPV 3017
Fly 3102 RNSVQCY----------QLENLSTRLD-CVQGPSEEGS--TDISSQFCYRGPALSGVI------- 3146
..:.:|: |.|...:|.| .::|| || ..:.|:.|: ||:
Mouse 3018 TTAPECWLAWSPLPNIQQQEVPRSRWDSTLKGP---GSLCRAVFSKCCF------GVLTNSSRAS 3073
Fly 3147 ------LSLICQPNGQLRSVPLSELLEWRSALQQTRHLIWEN----------------SQLLTSR 3189
|.|:...: |.|.|.:|....||....|:|.| ..|:..|
Mouse 3074 YWDVSGLPLLSSSH-----VTLGEWVERAQQLQDISSLLWTNMAVPSVAEFRRTDSRLQGLVLCR 3133
Fly 3190 YSGEVNNLLQA------KENARQLLKELEYVRKLSEKEQKANQ--GFENCAKELEKMI------- 3239
|...:..||.| .:|...|| |...:.....:|.... |.|...|||..::
Mouse 3134 YLLGLTELLPAHQRQEYMQNCEHLL--LGNTQAFHHVDQTMGNIGGQEALPKELLCLLLTSLHYF 3196
Fly 3240 --EKLEKEENNNASMTKDFEVSLTNALVGAIELCLLTNTPLIDPVEKNRLKNEYIAEDI------ 3296
|...|:....|:......||| |.:::.........||..|...|..|..:::
Mouse 3197 IGEGEGKQNLPEAARRGRLWVSL-----GLLQIQTWLPRARFDPAVKKAYKLRYAQDELRQLQCE 3256
Fly 3297 ----DCLSTLTTAYDFMKIAMKYRHFGEEIYSELELRLRTALQRQQQ-------LSQKLALRSEK 3350
:.||.|.|..|.. .:.|.|.....::...||..| ||:|.|.|...
Mouse 3257 LKTRNLLSHLQTGRDLE---------DDIITSHSHPHIKLLPQRISQLESLVHSLSKKQAFRPHL 3312
Fly 3351 CLYASLVQDITHFLHSNGDC----ESLYKLFQLIHSEWENFQGLHVATSAQLKSSIEVLGKLDLW 3411
..|.:|||:|.|::.|.... :.|.:|.|.:|::... |||:..:: |.:...|
Mouse 3313 PSYETLVQEIHHYVTSIAKVTAVQDLLMRLLQALHTDGPK--------SAQVLQNL--LKEEASW 3367
Fly 3412 LANAQRFVHHTLSRYSAYYQDFVEPIKCSVNQLRFGLESLKVIFTRVQQA--GSVSQAEQMQQTI 3474
..:..:|....:..| |.|.|.|.|:..|:.||:.| ::::.:.|..: ..|..||.:....
Mouse 3368 QQSHHQFRKRLVEEY-ALYPDTVAPLLASILQLQHG---MRLVASEVHASLHSGVLCAENLGALA 3428
Fly 3475 GDIVQFPSQHP---------------------------LVIRNSRLYGLLAELPHSEYEY---FR 3509
..::.|||..| :|.|.:| .|...|:..| .:
Mouse 3429 MAVLAFPSVGPSFPTYHAHADALCSVNAAEALRSLGKLMVKRAAR-----KEEAKSQQAYPTREQ 3488
Fly 3510 LLKAKLSELSNYIALGRVIDETTFAAYDDALSICNQTWQQEEHRRCQLKAEAE-SLYVTKTKGG- 3572
||...|..|.:::.....:|:.....:..........|.::| |..|.|||.| |||..:::.|
Mouse 3489 LLMNALLYLRSHVLCKGELDQRALLLFRHLCQEIINEWDEQE-RIAQEKAEQESSLYRYRSRSGR 3552
Fly 3573 -VDSEELIEMQEIEHNFPTNLDEDFAEFVSQPTLEQVLKLDKKASAKDKQSQIVVEEDYAFLARN 3636
..|||..|..|:...||.: ::|||:.:.:||||: |....|.:.:....:.......:
Mouse 3553 TALSEEEEEELELRKLFPLH-EKDFADILMEPTLEE------KKKVSDGREEEAAPDPTLLCQSS 3610
Fly 3637 FIDVMTRHTQ--------VYYKE--QPKSSKELELHLLAPYQARFQVFANLHGHYKTALGSSLEE 3691
...||..|.| ::|:: .|..:| |.|:.:.:.:|..|:|..|:...:|..|.:
Mouse 3611 MQAVMLIHQQLCLSFARSLWYQQAVPPHEAK----HYLSLFLSCYQTGASLVTHFYPLMGVELND 3671
Fly 3692 RACNGLAFGLALQQKQL-----RDIELEEGVSSSPYDFYKDSNISEIQSCLDVMERIEKRVLEQL 3751
:..........|....| .|:.:. ...|||||:..|::|.:.|..|::...:.|.:.|
Mouse 3672 QLLGSQLLACTLSSNTLCGEATSDLMMR---PDGPYDFYQHPNVAEARQCQPVLQGFSEAVSQLL 3733
Fly 3752 EQYPEHAGLADIKLVISRIRRLPAHAPVVRFNTGFQLLRQKLALWNEVAHRNNNLVSEEIEVAEF 3816
:.:|||..|..:.:|:.|||..|..:|:.:|..|.::|..|...|.|.|.|..:|......|::.
Mouse 3734 QDWPEHPVLQQLLVVMDRIRGFPLSSPISKFLNGLEILLAKAQDWEENASRVLSLRKHLDLVSQM 3798
Fly 3817 VQRWTRLELQHWRNCLGQTAAQVELQAYRYWFFIYNLLQQFIHQKQLDHSYTDIKLAEQRFAQDH 3881
:.||.:|||..|...|..|..:...::.::||.||.:|::.:.::
Mouse 3799 IIRWRKLELNCWSMSLDNTMIRHTEKSTKHWFSIYQMLEKHMQER-------------------- 3843
Fly 3882 LLDAQDLGESQRLELAQVVRILRQFVEASCYGDFHIRLQLLQGFELYLHNVERAGKINGLPPLIA 3946
.::..:.:::.|..:|..|:.|:|.|..|:||:|||:|..|..: |....::.|...|.:
Mouse 3844 ---TEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCH---VLLMPQVEGKDSLCS 3902
Fly 3947 ALHNLQLYFSQFAGEIADSAKLRRSPIEKKLKEFVKIQSYSKDLSYFSMRNSVASVHRNLNKFLK 4011
.|.||..::.||...:.......||||||:|||||||..:: |:|::|::.||...||.|.||:|
Mouse 3903 VLWNLYHFYKQFLDPVKAKIMELRSPIEKELKEFVKISKWN-DVSFWSIKQSVEKTHRTLFKFMK 3966
Fly 4012 EYRLSIQEKISEVFQPKD---------STAKDYTFGTDKGKGLRNYNKIKYLHTERQQFVASEKL 4067
::...:.|.........| ...::.|..|...:||.|
Mouse 3967 KFEAVLSEPCQSCLVESDKEEQPDCLPKPTEEATMETSPIQGLNN-------------------- 4011
Fly 4068 LEKFAIQEEFLS---------------------DNTLLQRLDKHFRTARHVVKETLGQVPYGELI 4111
|::|..|: :..||:||.:..:..|.:....:.:.|...|:
Mouse 4012 ----ALRETLLAQPVEWKPSGTEQCQDASPLSVEGELLRRLPRLSKRMRKMCLVFMKESPLPHLV 4072
Fly 4112 TELDDLLASQLERCEHLRSLNVDRSKERPQQKQEAKQILQQKRKALTDLFKMLHRLGANYKTGLL 4176
..||......:.....|:||.||.|.|:.:|..|||.||.||.:||:||||.|..:|.:|:.||.
Mouse 4073 ESLDQFTGGVISSVSELQSLKVDPSAEKEKQHSEAKHILLQKHRALSDLFKHLANIGLSYRKGLA 4137
Fly 4177 ELSLRNEFEDFQLPPYSIRSMLPRLHPTAQQLDEHL-----------DLYYMKSVFKLKLLQNIM 4230
....::..|...|.|..:||.|..:..| ::.|..| ..|:.:|:.:...|...:
Mouse 4138 WARSKSPQELLHLHPLDLRSALSIVSST-READSRLLTEISSLWDGCQKYFYRSLARHTRLTAAL 4201
Fly 4231 LTPLSELGPPNIERIKGFAVDLFLLVQQQREHLSGSTKELHELRNSLDSLRKLAEIIPQADINPS 4295
.||:.|:....|||.|||:..|..|:.:||..|:..|::...|||.|..::::...:....:.|.
Mouse 4202 ATPVKEVSMGTIERCKGFSAHLMKLLIRQRHSLTTLTEQWIILRNLLSCVQEIHSRLTGPPVYPV 4266
Fly 4296 TLNFVKSADIAMEIKQHL-RQIHYVLKQWKLLLSCAPS------------------SFIEESENR 4341
......|.....|..||| .|...:|:|:..|..|.|| |.:|..:.:
Mouse 4267 AFPPQDSVQQWTERLQHLAMQSQILLEQFSWLFQCCPSAEPTVGHRDAQVQEHPSASHLENIDFK 4331
Fly 4342 ---------LLVRKIS----LAQSELHSLC-----IQILNSSQELLNEL------NNANLEYLSS 4382
||...:| :..|:|.|.| .|:...|...|.|: ..|.::.:..
Mouse 4332 ETIAGVMPDLLSSDLSYPSPVPTSQLPSACRMRRQDQLWQQSTAGLTEMLKTIKTMKAGVDKIRQ 4396
Fly 4383 EKCVTYQKSY-------------AEIQENIKKTLEL-----LRTGQNDYLPLAQPIVELLDSVQL 4429
:.|.|...:: :::..:::....| :...|.| ....:||.||.::
Mouse 4397 QSCETLFHTWEDFEVCSSGLNCLSQVSAHLQGLASLFILPGIEVEQTD---SRMALVESLDYLR- 4457
Fly 4430 KNHTEIAPEAIDLANADTELANIAH-------------------------SVLMSMQKIYKHHVK 4469
.|:: :|||...|......:|| ::|.::|.:.:.:.|
Mouse 4458 ---GEVS-KAIDDFTAWKARLFVAHKQEGNQMVEESFVEDFSEQVETAIRAILCTIQNLAERNNK 4518
Fly 4470 ------TDEVNQNGEAKEQDEESKEALQEQHLKKCLTGELTSDWQQLSLPRVLGKLSNVLLVLKH 4528
.|:..|..:..:::|.|.::||..||.|.|..:..:....|.:.:::..:|.:|..||.
Mouse 4519 KAEDSAVDKRLQEEDGGKEEEASFKSLQPGHLTKLLEDDFWASVSTLHVQKIISSVSELLERLKS 4583
Fly 4529 SHFEG---KDKL------LCVRRAIGLLPVLEQYQLLADYLLLQQLATHKVSAKMLSIVLTVFVE 4584
...:| |.|: |.|| |:|:|..:..|..:.|...||||:.:||:||::...|.|
Mouse 4584 CSEDGNTTKHKVFSQSCGLLVR----LIPILCGFSDLVLFFLTVSLATHRSTAKLLSVLAQTFTE 4644
Fly 4585 IGSKGFCVPPDLMQDEEGQSKQESKNGEGFGLEDGTGENDASDKIESEDQLDDAKRPEDRKDEGD 4649
:..||||:|.:||:|..|:...:..:.||.|:.||.|..|.||:||:|:|::|..:....|||.|
Mouse 4645 LSQKGFCLPKELMEDSAGEGATQFHDYEGGGIGDGEGMKDVSDRIENEEQVEDTFQKGQEKDEED 4709
Fly 4650 -KQEPDCK-EEKGIEMSDDFDAKMQDVE-KPEEDDSGESEEEEDLNKEMGETE-EGAEKLDDQIW 4710
..:||.| |:..||||:|||.||.|.| :.||||.....|:.||:|:||... |.|:|||:::|
Mouse 4710 LDSKPDTKGEDNAIEMSEDFDGKMHDGELEQEEDDEKSDSEDGDLDKQMGNLNGEEADKLDERLW 4774
Fly 4711 GDDEEEKPE-----EEQEPDMNEEDQGKGSKDEK-DAHN-DLDTKNDAAKEDGKDEHEKDGLDAT 4768
||||||..: ||..|.::|||....:||:. ||.| :.:.|:...|||.:.|..:.|.:..
Mouse 4775 GDDEEEDEDGDGRAEETGPGVDEEDSELVAKDDSLDAGNLNKNKKHQDEKEDSEPEDVEQGQEKI 4839
Fly 4769 NEPSGEDKRKEQAKDIDDMKDPEMDEEQTNAMHNELEEPPEPEEMDLGDMNNVDE-----GHDDQ 4828
|| .||:. |.||.:.:..|...|:.||||.:||.|...:|. |.|..
Mouse 4840 NE------------QIDER---EYDENEVDPYHGNQEKLPEPEALDLPDDLKLDSEDKSGGEDTD 4889
Fly 4829 DEQPTDENPFDIDA----MKENMQPAEEPEA---DGDDEHDANEEGDPQSD--------GSDSEE 4878
:|:..:|||.:|.. |:|.....|||.| :|:..|:. ||| |..| |:|.::
Mouse 4890 NEEAEEENPLEIKEKTVDMEETDHEIEEPGAGQDEGESPHEP-EEG-PSEDKENMDMDTGADDQD 4952
Fly 4879 DEAGTEAKPAEEDHGEGEEATPEDEKDEAETQK-RGELEDEDDSKPEDSP-EDSKEEKEEKREEK 4941
.:..:.| |:|...|||..|:||.|.|..| ..:...|....|.|.. :..|||:||..:..
Mouse 4953 RDTSSHA----EEHSLEEEAEEEEEKGEKEEDKATTDGGGESGVNPVDQGLQPQKEEEEEGEQSD 5013
Fly 4942 PEEHSQSKDKASKEENVQSMPETDQSSSADQVQQPQDPDIKQDQKLDEQETGEEKDGVGQAE-ND 5005
.|| |..:...::|:. |...:..|.||..|..::. ....|:|.|:|:.|.|.|: |.
Mouse 5014 AEE--QVPEATERKEHA-----TCGQTGVDNVQSAQAVELA--GAAPEKEQGKEEHGSGAADANQ 5069
Fly 5006 ADDGGHQGVAETQETVSQEDRKNERQTQE-KRKQGRTNEERSLGEAEQNKLKQLKTIDQLKDSKE 5069
|: ||:.....:.:..|...|| ||. ||:.|:.:.|||:|:..:...|:|:|:.
Mouse 5070 AE--GHESNLIARLSSQQHTNKN---TQSFKRRPGQADNERSVGDYNERVRKRLRTVG------- 5122
Fly 5070 SDDAEQEKPEPMDQTEAEEYQHVKEPKNS-DKTTLDNATEEQSK--KIQHQEDEPPNEEEIEAEN 5131
:|...:::|......:|:.::|||:..:: |..|.|.|:.||.: |...|:.| |||||
Mouse 5123 TDRETEQEPTQAQVEDADAFEHVKQGSDAYDAQTYDVASSEQQQTAKASGQDQE---EEEIE--- 5181
Fly 5132 VDELMEAEEPAVDPEDDAELEQLGAEKTEQKSDKPS------------KTEKSKEQLETPEGMEI 5184
|.||:.||..:..|| .|||..|..:.::...| ||::.::...|....|.
Mouse 5182 -DILMDTEEELMRAED---TEQLKPEAVQSETAATSGSSEMEVDMQTLKTKEDQDPRTTTPHQET 5242
Fly 5185 EGEVVLTMTVPRSSETTAHSNSEILLDK--SSHAEDLSSAEQIELRQQYQKQLTTFRV-----AQ 5242
|.| ...||.::|.|:..:.|:|. ....:|:| ||||:.::||.|::. |:
Mouse 5243 ENE-----RPERSRDSTIHTLRQFLVDSVFQPILKDIS-----ELRQEMERQLETWQAHDYGNAE 5297
Fly 5243 PEHEDYETWQGISNRMTQNARELCEQLRLILEPTKCTRLKGDYRTGRRINMKKIIPYIASQFRKD 5307
.|....|.||.........:::|||||||:||||:..:|:||||||:|:||:|||||||||||||
Mouse 5298 EEKAAAEMWQNYLVLTASLSQQLCEQLRLLLEPTQAAKLRGDYRTGKRLNMRKIIPYIASQFRKD 5362
Fly 5308 KIWLRRTKPAQRDYKITIAIDDSKSMHHNNSKTLTLEAISLVSQALTLLESGRLSIVSFGEAPQI 5372
:||||||||::|.|:|.:|||||.||..|::|.|..|:::::..||||||.|::::.||||:.::
Mouse 5363 RIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGESVKL 5427
Fly 5373 ILNHTEQFD---GPRLVNALNFAQDKTKIAGLLNFIRT--ANAEESGTGGDNGLFEN-------L 5425
:....|||: |..::....|.|.|||||..|..:.. |.|:: |.:| |
Mouse 5428 LHPFHEQFNDSSGTHILRLCTFQQRKTKIAQFLETVAKMFAAAQK--------LSQNVSPETAQL 5484
Fly 5426 LLILSDGRNIFSEGAQNVKNAIKLARLQRIFLVYIIIDNPDNKNSILDIQHVAVNADGSV-NINS 5489
|||:||||.:|.||...|..|::.|:...||::::::|||::::|||||:.......|.: .|.|
Mouse 5485 LLIVSDGRGLFLEGKDRVLAAVQAAQNANIFVIFVVLDNPNSRDSILDIKVPIFKGPGEMPEIRS 5549
Fly 5490 YLDSFPFPYYVIVRDLNQLPLVLSEAMRQWFELVNS 5525
|::.||||:|:|:||:|.||..||:|:|||||||.:
Mouse 5550 YMEEFPFPFYIILRDVNALPETLSDALRQWFELVTA 5585
| 
