Protein Alignment Damm and CASP6

DIOPT Version :9

• Sequence 1: NP_001303345.1
• Gene: Damm / 36266
• FlyBaseID: FBgn0033659
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_001217.2
• Gene: CASP6 / 839
• HGNCID: 1507
• Length: 293
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 75/270 - (27%)
• Similarity: 120/270 - (44%)
• Gaps: 59/270 - (21%)

  Fly    24 EPGQGLDLNEKLKPPAVYILNHEQF------PQDSQLNRKGSSNDVNALRKTFESLKCRVEVISN 82
            :|.:...::.:.:..|: |.|||:|      |:     |:|:..|.:.|.:.|..|...|:..::
Human    32 DPAEKYKMDHRRRGIAL-IFNHERFFWHLTLPE-----RRGTCADRDNLTRRFSDLGFEVKCFND 90

  Fly    83 PALPDVKNKVKEWSAKRFTQDAGFVLFILSHGDRKEKILACDHREYHLDDDVLFPLFRNP---TL 144
            ....::..|:.|.|.........||...||||:... |.|.|.:   ::...|..||:..   :|
Human    91 LKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNH-IYAYDAK---IEIQTLTGLFKGDKCHSL 151

  Fly   145 SGKPKILIVQACKG--------PL---------------RADAKKMNNEP----YIKCYSCSEGY 182
            .|||||.|:|||:|        ||               ..||..:...|    ::.|||.:|||
Human   152 VGKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGY 216

  Fly   183 LSYRNENHGSVFIQTLCEAMDQYGLTRDFQSIFKHVKAEVERR-------STMTGSKQVP----- 235
            .|:|...:||.:||.|||.:.:||.:.:|..:...|..:|.:|       .:..|.||||
Human   217 YSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASM 281

  Fly   236 -SEESHNFDK 244
             :::.|.|.|
Human   282 LTKKLHFFPK 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Damm	NP_001303345.1	Peptidase_C14	42..248	CDD:279049	73/252 (29%)
CASP6	NP_001217.2	CASc	37..290	CDD:214521	72/262 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770