Protein Alignment Damm and CASP3

DIOPT Version :9

• Sequence 1: NP_001303345.1
• Gene: Damm / 36266
• FlyBaseID: FBgn0033659
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_001341706.1
• Gene: CASP3 / 836
• HGNCID: 1504
• Length: 277
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 77/280 - (27%)
• Similarity: 125/280 - (44%)
• Gaps: 66/280 - (23%)

  Fly    10 QKIERLYDSNRV-NAEP-----------GQGLDLNEKLKPPAV---YILNHEQFPQDSQL-NRKG 58
            :..|...||..: |.||           |..||.:.|:..|.:   .|:|::.|.:.:.: :|.|
Human     2 ENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG 66

  Fly    59 SSNDVNALRKTFESLKCRVEVISNPALPDVKNKVKEWSAKRFTQDAGFVLFILSHGDRKEKILAC 123
            :..|...||:||.:||..|...::....::...:::.|.:..::.:.||..:||||:  |.|:..
Human    67 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGE--EGIIFG 129

  Fly   124 DHREYHLDDDVLFPLFRNP---TLSGKPKILIVQACKG----------------------PLRAD 163
            .:....|.....|  ||..   :|:||||:.|:|||:|                      |:.||
Human   130 TNGPVDLKKITNF--FRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEAD 192

  Fly   164 AKKMNNEPYIKCYSCSEGYLSYRNENHGSVFIQTLCEAMDQYGLTRDFQSIFKHVKAEVERRSTM 228
                    ::..||.:.||.|:||...||.|||:||..:.||....:|.    |:...|.|:
Human   193 --------FLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFM----HILTRVNRK--- 242

  Fly   229 TGSKQVPSE-ESHNFDKPFY 247
                 |.:| ||.:||..|:
Human   243 -----VATEFESFSFDATFH 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Damm	NP_001303345.1	Peptidase_C14	42..248	CDD:279049	66/233 (28%)
CASP3	NP_001341706.1	CASc	37..277	CDD:214521	68/245 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770