DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Damm and caspa

DIOPT Version :9

Sequence 1:	NP_001303345.1	Gene:	Damm / 36266	FlyBaseID:	FBgn0033659	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_571580.1	Gene:	caspa / 57933	ZFINID:	ZDB-GENE-000616-3	Length:	383	Species:	Danio rerio

Alignment Length:	259	Identity:	59/259 - (22%)
Similarity:	113/259 - (43%)	Gaps:	34/259 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 NRVNAEPGQ-GLDLNEK-LKPPAVYILNHEQFPQDSQLNRKGSSNDVNALRKTFESLKCRVEVIS 81
            |::..|.|| ..::.:| ::.....::|:..| .|..:.|.||..|...:.|..:.|..:|....
Zfish   124 NKILREKGQETYEIKDKSVRKRLALLINNVDF-DDKAMKRSGSEKDEENMEKLLKELDYQVVKRP 187

  Fly    82 NPALPDVKNKVKEWSAKRFTQ--DAGFVLFILSHGDRKEKILACDHREYHLDDDVLFP---LFRN 141
            |.:..::...:::::.:...:  |:.||: |:|||.|...:....||..:..|.  ||   ::|.
Zfish   188 NLSAKEMDEAIRDFAQREEHKYSDSAFVV-IMSHGKRDAIMGVHYHRTNNPSDS--FPVDNVYRR 249

  Fly   142 ------PTLSGKPKILIVQACKGPLRADAKKMNNEP-----------------YIKCYSCSEGYL 183
                  |.|..|||::::|||:|.........:.||                 :|...||:....
Zfish   250 LNSENCPALRDKPKVILIQACRGGEHGRVWASDGEPDEPIEIEDDDFVHKEKDFISLMSCTPDTK 314

  Fly   184 SYRNENHGSVFIQTLCEAMDQYGLTRDFQSIFKHVKAEVERRSTMTGSKQVPSEESHNFDKPFY 247
            |||:..:|:.::|||.:...:.......:.:|:.|....|..:.:...||:..::.....|.||
Zfish   315 SYRHVQNGTFYVQTLVDVFIKCAHEDHIEELFRKVLRRFEHPNMIGNFKQMACKDRATLPKLFY 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Damm	NP_001303345.1	Peptidase_C14	42..248	CDD:279049	54/234 (23%)
caspa	NP_571580.1	DD	6..85	CDD:417479
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	87..106
		CASc	134..380	CDD:237997	55/249 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810