DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Damm and cflara

DIOPT Version :9

Sequence 1:	NP_001303345.1	Gene:	Damm / 36266	FlyBaseID:	FBgn0033659	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001300701.1	Gene:	cflara / 373114	ZFINID:	ZDB-GENE-030826-3	Length:	461	Species:	Danio rerio

Alignment Length:	251	Identity:	57/251 - (22%)
Similarity:	93/251 - (37%)	Gaps:	50/251 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KLKPPAVYILNHEQFPQDSQLN--RKG-------SSNDVNALRKTFESLKCRVEVISNPALPDVK 89
            ||..|...|...:...::.|:|  ::|       ...|...|:.|||.|..:|...|...|.:.:
Zfish   223 KLSVPETGIHYQQAITEEYQMNPEQRGLCVIIDCVGYDGEMLKHTFECLGFKVVFHSLLGLKETQ 287

  Fly    90 NKVKEWSAKRFTQDAG-FVLFILSHGDRKEKILACDHREYHLDDDVLFPLFRNPTLSGKPKILIV 153
            ..:::.|..|..|... ||..::|.|.... :||.|.....::...|..|| |.|..  |||...
Zfish   288 KVLEDLSLNRILQRVRCFVCCLISRGTNTH-LLATDSNRLGINLKDLKQLF-NATKC--PKIFFT 348

  Fly   154 QACKGPLRADAKKMNNEPYIKCYSCSEGYLSYRNENHGSV-----FIQTLCEA----MDQYGLTR 209
            |..:.........|::|     |..::...|.:..|.|||     .:.::|.|    :::.|
Zfish   349 QLYRITEAPVMPSMDDE-----YLETDAPASRQCSNTGSVPMPADVLWSVCTAEVKLLEESG--- 405

  Fly   210 DFQSIFKH------------------VKAEVERRSTMTGSKQVPSEESHNFDKPFY 247
             .||::.:                  |..||:|......|.....::||...|..|
Zfish   406 -HQSVYLNALNNALLKGHERNVPILDVMKEVQRNVLSHDSDNYQLQQSHTLQKKLY 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Damm	NP_001303345.1	Peptidase_C14	42..248	CDD:279049	54/243 (22%)
cflara	NP_001300701.1	DED	8..87	CDD:307481
		DED_c-FLIP_r2	100..180	CDD:260046
		CASc	241..461	CDD:320727	53/233 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900