DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Damm and caspb

DIOPT Version :9

Sequence 1:	NP_001303345.1	Gene:	Damm / 36266	FlyBaseID:	FBgn0033659	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_690840.2	Gene:	caspb / 259303	ZFINID:	ZDB-GENE-020812-1	Length:	404	Species:	Danio rerio

Alignment Length:	231	Identity:	61/231 - (26%)
Similarity:	100/231 - (43%)	Gaps:	34/231 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 ILNHEQFPQDSQLNRKGSSNDVNALRKTFESLKCRVEVISNPALPDVKNKVKEWSAKRFTQDAG- 105
            ::.:.|| .::|.||.|:..|.........||...|....|.:..|::..|:.:|.:|..:||.
Zfish   178 LITNIQF-ANTQHNRNGADRDEENAEWLLRSLGFAVIKYRNLSGKDIRRAVENFSKRREHEDADS 241

  Fly   106 -FVLFILSHG---DRKEKILACDHREYHLDDDVLF--PLFRN------PTLSGKPKILIVQACKG 158
             |:: |:|||   |.|:.|:.       :.|||.|  ..|.:      |.|..|||::::|||:|
Zfish   242 TFIV-IMSHGTRIDNKDAIVG-------VSDDVYFIEETFSHLNSVNCPALIDKPKVILIQACRG 298

  Fly   159 ----------PLRADAKKMNNEPYIKCY-SCSEGYLSYRNENHGSVFIQTLCEAMDQYGLTRDFQ 212
                      .:.|....::.|....|: |......:|||...||.||..:.:.........|..
Zfish   299 GQSSGVLAQDSVFASDSWVHMEKDFVCFMSTMPNTFAYRNPIEGSFFISYIVDVFCSSAHRDDIM 363

  Fly   213 SIFKHVKAEVERRSTMTG-SKQVPSEESHNFDKPFY 247
            .:|:.|...:|:.....| :|.:|..|..:..|.||
Zfish   364 ELFRKVTLRMEKDQRFQGQAKLLPCIERTSISKRFY 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Damm	NP_001303345.1	Peptidase_C14	42..248	CDD:279049	61/231 (26%)
caspb	NP_690840.2	Pyrin_ASC-like	5..84	CDD:260033
caspb	NP_690840.2	CASc	163..401	CDD:237997	61/231 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810