Protein Alignment Damm and Casp6

DIOPT Version :10

• Sequence 1: NP_523703.2
• Gene: Damm / 36266
• FlyBaseID: FBgn0033659
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_033941.3
• Gene: Casp6 / 12368
• MGIID: 1312921
• Length: 276
• Species: Mus musculus
• Alignment Length: 278
• Identity: 77/278 - (27%)
• Similarity: 124/278 - (44%)
• Gaps: 59/278 - (21%)

  Fly    16 YDSNRVNAEPGQGLDLNEKLKPPAVYILNHEQF------PQDSQLNRKGSSNDVNALRKTFESLK 74
            |.|..| .:|.:...::.|.:..|: |.|||:|      |:     |:|::.|.:.|.:.|..|.
Mouse     8 YKSREV-FDPAEQYKMDHKRRGVAL-IFNHERFFWHLTLPE-----RRGTNADRDNLTRRFSDLG 65

  Fly    75 CRVEVISNPALPDVKNKVKEWSAKRFTQDAGFVLFILSHGDRKEKILACDHREYHLDDDVLFPLF 139
            ..|:..::....::..|:.|.|.........|:...||||:... :.|.|.:   ::...|..||
Mouse    66 FEVKCFNDLRAEELLLKIHEVSTSSHIDADCFICVFLSHGEGNH-VYAYDAK---IEIQTLTGLF 126

  Fly   140 RN---PTLSGKPKILIVQACKG--------PL--------------RADAKKMNNEP----YIKC 175
            :.   .:|.|||||.|:|||:|        ||              :.||..:...|    ::.|
Mouse   127 KGDKCQSLVGKPKIFIIQACRGSQHDVPVVPLDMVDHQTDKLDNVTQVDAASVYTLPAGADFLMC 191

  Fly   176 YSCSEGYLSYRNENHGSVFIQTLCEAMDQYGLTRDFQSIFKHVKAEVERRST-------MTGSKQ 233
            ||.:|||.|:|...:||.:||.|||.:.:||.:.:|..:...|..:|.:|..       ..|.||
Mouse   192 YSVAEGYYSHRETVNGSWYIQDLCEMLARYGSSLEFTELLTLVNRKVSQRRVDFCKDPDAIGKKQ 256

  Fly   234 VP------SEESHNFDKP 245
            ||      :::.|...||
Mouse   257 VPCFASMLTKKLHFCPKP 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Damm	NP_523703.2	Peptidase_C14	42..247	CDD:425803	71/252 (28%)
Casp6	NP_033941.3	CASc	20..272	CDD:214521	71/261 (27%)
		Tri-arginine exosite. /evidence=ECO:0000250|UniProtKB:P55212	25..27		1/1 (100%)
		130's region. /evidence=ECO:0000250|UniProtKB:P55212	108..125		3/20 (15%)