DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Damm and casp2

DIOPT Version :9

Sequence 1:	NP_001303345.1	Gene:	Damm / 36266	FlyBaseID:	FBgn0033659	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_012809163.2	Gene:	casp2 / 100486813	XenbaseID:	XB-GENE-482390	Length:	421	Species:	Xenopus tropicalis

Alignment Length:	266	Identity:	64/266 - (24%)
Similarity:	102/266 - (38%)	Gaps:	58/266 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TEHQKIERLYDSNRVNAEPGQGLDLNEKLKPPAVYILNHEQFPQDSQLNRKGSSNDVNALRKTFE 71
            :.||:..:::...|     |:.|            |:::..|......:|.|...||.:|.|.|.
Frog   156 SHHQQAYKMHSCPR-----GRAL------------IISNVAFETQDLDHRYGGEVDVASLEKLFS 203

  Fly    72 SLKCRVEVISNPALPDVKNKVKEWSA--KRFTQDAGFVLFILSHGDRKEKILACDHREYHLDDDV 134
            ||..:|||..|....::.:::..:||  .....|: .|:.:|||| ....:...|.:...|.|
Frog   204 SLGFQVEVRRNLNAQNMMSQLGAFSALPAHSALDS-CVVAVLSHG-LDGAVYGTDGKLVQLQD-- 264

  Fly   135 LFPLFRN---PTLSGKPKILIVQACKGPL------RADAKKMNNEP------------------- 171
            :|....|   |.|..|||:..:|||:|..      :.|.::.:..|
Frog   265 VFTAMDNAHCPQLQNKPKMFFIQACRGEEADRGVDQRDGREQSASPGCEQSDAGREDIKVRLPTQ 329

  Fly   172 --YIKCYSCSEGYLSYRNENHGSVFIQTLCEAMDQYGLTRDFQSIFKHVKAEVERRSTMTGSKQV 234
              .|..|:|.:|.:|.||...||.|:|.|.....||........:...|.|.::.|     ....
Frog   330 SDMICAYACLKGTVSLRNTKRGSWFVQDLVSVFSQYSKNTHVADMLVKVNALIKER-----EGHA 389

  Fly   235 PSEESH 240
            |..|.|
Frog   390 PGTEFH 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Damm	NP_001303345.1	Peptidase_C14	42..248	CDD:279049	59/231 (26%)
casp2	XP_012809163.2	DD	5..86	CDD:417479
casp2	XP_012809163.2	CASc	161..414	CDD:237997	62/261 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910