Protein Alignment Sln and SLC16A7

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: XP_011537291.1
• Gene: SLC16A7 / 9194
• HGNCID: 10928
• Length: 504
• Species: Homo sapiens
• Alignment Length: 676
• Identity: 148/676 - (21%)
• Similarity: 246/676 - (36%)
• Gaps: 258/676 - (38%)

  Fly   218 SGGPNVEPPDGGYGWFIVFGAF-SVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILSAL 281
            |..|...|||||:||.:|..|| |:.|..| ..|:..|.:.||.:.|.::.:.:| ||.:|:.|:
Human     6 SAPPVHPPPDGGWGWIVVGAAFISIGFSYA-FPKAVTVFFKEIQQIFHTTYSEIA-WISSIMLAV 68

  Fly   282 CLV--------------------------LAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYFAT 320
            ...                          |.|:||.|..::..|.||..||:.|.:||:|:.|::
Human    69 MYAGGRIFESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSS 133

  Fly   321 SLLHLLLTFGVLTGIGGGLSTTPGIVIVSQYFDKHRALANGICVSGTAAGSFILPVLIKHLA--- 382
            |::.|.||.|.:||:|...:..|.:.|:.:||.:.|.:|||:.::|:       ||.:..||
Human   134 SVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS-------PVFLSSLAPFN 191

  Fly   383 ----ENCGFHGTILILGGCMLHVCVSATLYRPISAYTDQDSGQGQEETAKPLNEDINPSTTGILT 443
                ...|:.|:.||||..:|:.||:.:|.||:        |..|                   |
Human   192 QYLFNTFGWKGSFLILGSLLLNACVAGSLMRPL--------GPNQ-------------------T 229

  Fly   444 TSTYLDTCDVGAGHELSDKFIEHLFLEESKNHLNYYASKQPAQDKSAQESDDEVKDIIGETTFIK 508
            ||                         :|||             |:.:..||.           .
Human   230 TS-------------------------KSKN-------------KTGKTEDDS-----------S 245

  Fly   509 PMKKVRSSGLLHSVEDLSTDSTWVYRKHSGTDSNRGSRRRRNVFANDEVISKIQAHLEKPLSPPS 573
            | ||:::.           .|||
Human   246 P-KKIKTK-----------KSTW------------------------------------------ 256

  Fly   574 VVSRGLSKSMEIPTPVSNLSDLKQQPVEQAELGILDSQLVESIIDGDGHLAADEDDDDDEERGPR 638
                                                                             
Human   257 ----------------------------------------------------------------- 256

  Fly   639 TCCERIEMYLDISLLQDPSFILMCLSVTLMSVGCPYMLYYLPAHVISIGYNKSEAGYLVAISAVL 703
               |::..|||.||.:...|::......:|.:|....:.:|..:....|.::..|.:|:::.|.:
Human   257 ---EKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFV 318

  Fly   704 DLIGRLGLGWLCD-------LQLFDRKKTYTLCILGAGCAVLTIPFAKTLVLVGLSAAVYGLCLG 761
            |:..|..:|.:.:       :|.|     ::..|:..|...|..|.|:....:.|.|..:||..|
Human   319 DMFARPSVGLIANSKYIRPRIQYF-----FSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFG 378

  Fly   762 SWYVLMPVLLADVFGTDRISSSYGLVRMFQSIGAISVPPLAGLMRDLSGDYEICFYCMGSCMVLG 826
            |...::...|.|:.|..|.||:.|||.:.:....:..|||||.:.||:|:|:..:...|:.:|..
Human   379 SVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAA 443

  Fly   827 TTPLIVWSIL-EARNHRLFVQREEEE 851
            :    ||.:: .|.|:||..:..:||
Human   444 S----VWLLIGNAINYRLLAKERKEE 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	63/209 (30%)
		MFS	<656..827	CDD:119392	44/177 (25%)
		MFS_1	658..>847	CDD:284993	50/196 (26%)
SLC16A7	XP_011537291.1	2A0113	15..484	CDD:273325	144/667 (22%)
		MFS	20..449	CDD:119392	134/644 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750