Protein Alignment Sln and SLC16A3

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001035887.1
• Gene: SLC16A3 / 9123
• HGNCID: 10924
• Length: 465
• Species: Homo sapiens
• Alignment Length: 655
• Identity: 133/655 - (20%)
• Similarity: 225/655 - (34%)
• Gaps: 252/655 - (38%)

  Fly   217 ESGGPNVEPPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFP---SSTATVASWIPAIL 278
            :.|...|:.||||:||.::||.|.:..:.....|:..|.:.|:::.|.   |.||    ||.:||
Human     7 DEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTA----WISSIL 67

  Fly   279 SALCLVLAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTP 343
            .|:.....||.|....||.||.|:.|||:|.::||:.:.|..|::.:.||.||:||:|..|:..|
Human    68 LAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQP 132

  Fly   344 GIVIVSQYFDKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLY 408
            .::::::||.|.|.:|||:..:|:......|..|.:.|.:..|:.|..|||||.:|:.||.|.|.
Human   133 SLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALM 197

  Fly   409 RPISAYTDQDSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESK 473
            ||:..            ||:|
Human   198 RPLVV------------TAQP-------------------------------------------- 206

  Fly   474 NHLNYYASKQPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSG 538
                                                                            |
Human   207 ----------------------------------------------------------------G 207

  Fly   539 TDSNRGSRRRRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQA 603
            :...|.|||
Human   208 SGPPRPSRR-------------------------------------------------------- 216

  Fly   604 ELGILDSQLVESIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQDPSFILMCLSVTLM 668
                                                       .||:|:.:|..|:|..::.::|
Human   217 -------------------------------------------LLDLSVFRDRGFVLYAVAASVM 238

  Fly   669 SVGCPYMLYYLPAHVIS----IGYNKSEAGYLVAISAVLDLIGRLGLGWLCDLQLFDRKKTYTLC 729
            .:|    |:..|..|:|    :|...::|.:|:.|...:|:..|...|::..|   .:.:.|::.
Human   239 VLG----LFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGL---GKVRPYSVY 296

  Fly   730 ILGAGCAVLTIPFAKTLVLVGLSAAVYG----LCL--GSWYVLMPVL----LADVFGTDRISSSY 784
            :..     .::.|.....|.|.:|..||    .|:  |..|.::..|    |..:.||.:.||:.
Human   297 LFS-----FSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAI 356

  Fly   785 GLVRMFQSIGAISVPPLAGLMRDLSGDYEICFYCMGSCMVLGTTPLIVWSILEARNHRLFVQREE 849
            |||.:.:::..:..||..|.:.|.:..|...|...|:.::..:..|::.:....|......|.|.
Human   357 GLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEV 421

  Fly   850 EECEE 854
            ...||
Human   422 AAAEE 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	64/178 (36%)
		MFS	<656..827	CDD:119392	42/184 (23%)
		MFS_1	658..>847	CDD:284993	44/202 (22%)
SLC16A3	NP_001035887.1	2A0111	8..444	CDD:331689	133/654 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..438		3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145586
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.950