Protein Alignment Sln and SLC16A5

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: XP_005257847.1
• Gene: SLC16A5 / 9121
• HGNCID: 10926
• Length: 545
• Species: Homo sapiens
• Alignment Length: 599
• Identity: 117/599 - (19%)
• Similarity: 192/599 - (32%)
• Gaps: 208/599 - (34%)

  Fly   223 VEPPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILSALCLVLAP 287
            :|..||.:.|.::......|....|.....|:.:.|:...|.:|.:. .||.|:||:|:..:..|
Human    45 LERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSE-TSWFPSILTAVLHMAGP 108

  Fly   288 LSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPGIVIVSQYF 352
            |.|.|..||.||..|.:||:..::||:.|.|:.:|..|..|.|.:||:|...|....|.::..||
Human   109 LCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYF 173

  Fly   353 DKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLYRPISAYTDQ 417
            .:.|.|||.:...|.:.|..:.|:|.::|.||.|:.||.|:.||..||.|:...:.||::
Human   174 VRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVA----- 233

  Fly   418 DSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESKNHLNYYASK 482
                                                                             
Human   234 ----------------------------------------------------------------- 233

  Fly   483 QPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSGTDSNRGSRR 547
                                  |.:.|..|
Human   234 ----------------------TSVAPETK----------------------------------- 241

  Fly   548 RRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQAELGILDSQL 612
                                                |.|.|          |.|...||.|
Human   242 ------------------------------------ECPPP----------PPETPALGCL---- 256

  Fly   613 VESIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQ-DPSFILMCLSVTLMSVGCPYML 676
                                     ..|...|:.:|...:|: :..:.:..|.|....:|.|...
Human   257 -------------------------AACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQ 296

  Fly   677 YYLPAHVISIGYNKSEAGYLVAISAVLDLIGRLGLGWLCDLQLF--DRKKTYTLCILGAGCAVLT 739
            .:|..:.:....::.:|..|::|....::..|...|.:.....|  .||..::|.:|..|...|.
Human   297 VFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLV 361

  Fly   740 IPFAKTL-VLVGLSAAVYGLCLGSWYVLMPVLLADVFGTDRISSSYGLVRMFQSIGAISVPPLAG 803
            ...:... ||||...| |.:.:.....|:..:|.|:...|:...:.||..:...:..:..|||||
Human   362 CAASGDFWVLVGYCLA-YSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAG 425

  Fly   804 LMRDLSGDYEICFY 817
            |:.|.:.::...||
Human   426 LLLDATNNFSYVFY 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	59/175 (34%)
		MFS	<656..827	CDD:119392	38/165 (23%)
		MFS_1	658..>847	CDD:284993	38/163 (23%)
SLC16A5	XP_005257847.1	2A0113	41..493	CDD:273325	117/599 (20%)
		MFS	54..452	CDD:119392	114/590 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145541
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.850